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Translation
King James Version
And when they found him not, they turned back again to Jerusalem, seeking him.
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KJV (with Strong's)
And G2532 when they found G2147 him G846 not G3361, they turned back again G5290 to G1519 Jerusalem G2419, seeking G2212 him G846.
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Complete Jewish Bible
Failing to find him, they returned to Yerushalayim to look for him.
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Berean Standard Bible
When they could not find Him, they returned to Jerusalem to search for Him.
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American Standard Version
and when they found him not, they returned to Jerusalem, seeking for him.
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World English Bible Messianic
When they didn’t find him, they returned to Jerusalem, looking for him.
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Geneva Bible (1599)
And when they found him not, they turned backe to Hierusalem, and sought him.
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Young's Literal Translation
and not having found him, they turned back to Jerusalem seeking him.
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In the KJVVerse 25,019 of 31,102

Study This Verse

SUMMARY

Luke 2:45 vividly portrays the profound anxiety and immediate action of Mary and Joseph upon realizing their twelve-year-old son, Jesus, was not among their traveling party. After a day's journey away from Jerusalem, their assumption that He was with relatives or friends proved false, prompting their urgent and determined decision to turn back to the city they had just left, embarking on a diligent search for Him. This verse underscores their parental concern and sets the stage for the remarkable discovery of Jesus in the Temple.

CONTEXT

  • Literary Context: This verse is an integral part of the unique Lukan account of Jesus' childhood visit to Jerusalem for the Passover festival, specifically detailing the aftermath of His parents' discovery that He was missing. The preceding verses establish the annual pilgrimage custom (Luke 2:41), the family's journey, and their initial assumption that Jesus was among their large group of relatives and acquaintances (Luke 2:42-44). Luke 2:45 marks the critical turning point where their casual assumption gives way to frantic realization and immediate action, leading directly into the three-day search and the eventual finding of Jesus in the Temple courts, engaging with the teachers (Luke 2:46-47). The narrative highlights the human side of Jesus' upbringing, the parental responsibilities of Mary and Joseph, and subtly foreshadows Jesus' singular focus on His Father's business, as revealed in Luke 2:49.
  • Historical & Cultural Context: The annual pilgrimage to Jerusalem for Passover was a deeply ingrained religious and cultural practice for Jewish families, mandated by the Law (Deuteronomy 16:16). Travel during these festivals often involved large caravans or groups of families and friends from the same village or region, providing safety and companionship. Children, especially boys nearing adulthood, would often travel independently within these large groups, moving between family units. It was therefore not unusual for parents to assume their child was with another relative or friend in the expansive caravan, particularly at the end of a day's journey when the group would settle for the night. The realization that Jesus was missing after a full day's travel (approximately 15-20 miles from Jerusalem) underscores the significant distance Mary and Joseph had to retrace, highlighting the depth of their concern and the urgency of their mission. Jerusalem itself was a bustling city, especially during festivals, making the task of finding a lost child particularly daunting.
  • Key Themes: Luke 2:45 contributes significantly to several key themes within the Gospel of Luke and the broader biblical narrative. Firstly, it powerfully illustrates Parental Diligence and Concern, showcasing Mary and Joseph's deep love and responsibility for Jesus. Their immediate decision to reverse a day's journey to search for Him emphasizes the profound bond and commitment inherent in their role. Secondly, the act of Seeking is central; the parents' urgent search for Jesus foreshadows the broader human need to seek God and His Messiah. This theme resonates with Jesus' own mission to seek and save the lost and the call for believers to seek first the kingdom of God. Lastly, this incident subtly introduces the theme of Jesus' Unique Identity and Divine Purpose. While His parents sought Him out of natural concern, Jesus was already engaged in His Father's business, a truth that would become increasingly evident throughout His ministry. Their temporary "loss" of Jesus highlights the growing chasm between human understanding and divine reality, a theme explored further as Jesus matures and begins His public ministry, often misunderstood even by those closest to Him (Mark 3:21).

EXPOSITION AND ANALYSIS

Key Word Analysis

  • found (Greek, heurískō', G3361): This verb signifies to discover, obtain, or perceive. In this context, it denotes the act of realizing Jesus' absence, a discovery that prompts immediate and intense parental distress. The use of the negative particle "not" (G3361, mḗ) with this verb emphasizes the failure of their initial assumption and the shocking nature of their realization.
  • turned back again (Greek, hypostréphō', G5290): This compound verb means "to turn under (behind)" or "to return." It highlights the reversal of their journey, a physically demanding and emotionally charged act. The "again" underscores that they were retracing their steps, driven by necessity and urgency, abandoning their homeward journey to rectify a grave oversight.
  • seeking (Greek, zētéō', G2212): This verb implies a diligent, earnest, and often persistent search. It is not a casual looking but an active, focused pursuit. In the context of Mary and Joseph, it conveys their intense determination to locate Jesus, reflecting profound anxiety and commitment. This word can also carry spiritual connotations of seeking God or His will, adding a layer of thematic depth to their physical search.

Verse Breakdown

  • "And when they found him not": This clause describes the crucial moment of realization for Mary and Joseph. After a full day's journey from Jerusalem, they conducted a more thorough check within their traveling party, only to discover that Jesus was definitively absent. This finding was not merely a lack of presence but a profound and alarming discovery of His disappearance, shattering their initial assumption and sparking intense parental concern.
  • "they turned back again to Jerusalem": This phrase details their immediate and decisive response to the realization. Despite having traveled a significant distance, they reversed their direction, abandoning their homeward journey. This action underscores the urgency and depth of their concern, prioritizing the search for their son over their own travel plans or comfort. Returning to Jerusalem meant retracing their steps into a crowded, bustling city, a challenging environment for a search.
  • "seeking him": This final clause clarifies the purpose of their return. Their journey back was not for any other reason but solely to find Jesus. The verb "seeking" implies a diligent, earnest, and persistent search, indicating that they would not rest until they had located their son. This highlights their unwavering commitment and the profound anxiety that propelled their actions.

Literary Devices

Luke 2:45 employs several literary devices to convey its meaning and emotional impact. The primary device is Pathos, evoking deep sympathy and empathy for Mary and Joseph's distress. The description of their realization ("found him not") and their immediate, desperate action ("turned back again...seeking him") powerfully communicates the universal anxiety of parents who have lost a child. There is also an element of Irony in the narrative: the parents are diligently seeking Jesus, unaware that He is not lost in the conventional sense but is purposefully engaged in His divine calling in the Temple. This sets up the dramatic reveal in the subsequent verses. Furthermore, the act of "seeking" can be seen as Symbolism, foreshadowing humanity's spiritual quest for the Messiah and the diligent effort required to find and follow Him. The narrative structure itself, moving from assumption to discovery to urgent search, builds Suspense, drawing the reader into the parents' predicament and anticipating the outcome of their search.

THEOLOGICAL AND THEMATIC CONNECTIONS

The anxious search of Mary and Joseph for Jesus in Luke 2:45 holds significant theological weight beyond a simple narrative of a lost child. It underscores the profound value of Jesus, even in His youth, and the natural human desire to seek what is precious and seemingly lost. The parents' diligent pursuit reflects a spiritual truth: humanity, often unaware of God's presence or purpose, must actively seek Him. This narrative, though focused on a physical search, points to the spiritual journey of seeking understanding, wisdom, and the divine presence. It reminds us that even those closest to God (like Mary and Joseph) can experience moments of confusion or "loss" regarding His ways, necessitating a return to the "center" (Jerusalem/Temple) and a diligent search for clarity and connection. This diligent seeking is often met with divine revelation, as Mary and Joseph's search ultimately led them to a deeper, albeit still developing, understanding of Jesus' unique identity.

REFLECTION AND APPLICATION

The narrative of Mary and Joseph's frantic search for Jesus in Luke 2:45 offers profound lessons for contemporary believers. Just as they diligently retraced their steps and sought Jesus, we are called to a similar spiritual diligence in our relationship with God. In moments of spiritual dryness, doubt, or perceived distance from Christ, this verse encourages us not to passively wait but to actively "turn back" to the foundational truths of our faith and engage in a fervent search through prayer, Scripture study, worship, and fellowship. It reminds us that spiritual "lostness" can affect anyone, even those deeply committed, and that the path to rediscovery often involves intentional effort and a willingness to retrace our steps to where we last knew His presence. For parents, it serves as a poignant reminder of the immense responsibility and love involved in nurturing children, both physically and spiritually, and the urgent action required when their well-being is at stake. Furthermore, the story offers comfort, illustrating that even Jesus' earthly parents, though righteous, did not always fully comprehend His divine nature or mission, leading to moments of confusion. This reassures us that misunderstandings can be part of our spiritual journey, but diligent seeking ultimately leads to deeper understanding and renewed connection with God's perfect will.

Questions for Reflection

  • In what areas of your spiritual life do you feel a sense of "lostness" or distance from Christ, and what steps are you willing to take to "turn back" and diligently seek Him?
  • How does Mary and Joseph's immediate and determined response challenge you to prioritize your spiritual pursuits over convenience or comfort?
  • What does this narrative teach us about the nature of seeking God, and how can we cultivate a more persistent and earnest search in our daily lives?
  • Considering that even Jesus' parents experienced moments of misunderstanding, how does this encourage you in your own journey of faith when things are unclear?

FAQ

Why didn't Mary and Joseph realize Jesus was missing sooner, especially after a full day's journey?

Answer: The cultural context of the time provides the primary explanation. Jewish families traveling to and from Jerusalem for festivals like Passover often did so in large caravans, comprising extended family, friends, and villagers. Within these large groups, children, especially boys nearing the age of adulthood like Jesus at twelve, had a degree of freedom to move between different family units. It was common for parents to assume their child was with other relatives or friends within the caravan. Mary and Joseph likely made this assumption, perhaps checking with close kin at various points, and only at the end of the day's journey, when the group settled for the night, did they conduct a more thorough and alarming check, realizing Jesus was definitively not among them. This highlights the scale of these travel groups and the trust placed within the community network.

What is the significance of Jesus being found in the Temple, rather than just anywhere in Jerusalem?

Answer: The significance of Jesus being found in the Temple is profound and multi-layered. Firstly, it immediately reveals His unique relationship with God the Father and His burgeoning awareness of His divine identity and mission. His response to His parents, "Did you not know that I must be about my Father's business?", underscores that the Temple, as His Father's house, was His rightful place of engagement. Secondly, His activity there—listening to and questioning the teachers (Luke 2:46-47)—demonstrates His extraordinary wisdom and understanding, astonishing those present. This scene serves as a powerful foreshadowing of His later public ministry, where He would teach with authority in the Temple and challenge the religious establishment. It marks the first recorded words of Jesus in the Gospels, establishing His divine focus and purpose from an early age.

CHRIST-CENTERED FULFILLMENT

The anxious search of Mary and Joseph for Jesus in Luke 2:45, while a deeply human and relatable experience, finds its profound Christ-centered fulfillment in the broader narrative of humanity's spiritual condition and God's redemptive plan. Just as Jesus' earthly parents diligently sought Him, the entire human race, since the fall, has been in a state of spiritual "lostness," separated from God and in desperate need of a Savior. Yet, the beautiful irony is that while humanity was "lost" in its sin, it was Jesus, the Son of Man, who came to seek and to save that which was lost. He is not merely the one sought, but the ultimate Seeker. The parents' physical journey back to Jerusalem to find their son foreshadows the spiritual journey of repentance and faith, where humanity must "turn back" to God to find life in Christ. Jesus Himself declares, "I am the way, the truth, and the life. No one comes to the Father except through Me". He is the one in whom all wisdom and knowledge are hidden (Colossians 2:3), the ultimate "find" for every seeking heart. His presence in the Temple, engaged in His Father's business, reveals that He was never truly lost, but always about the work of salvation, waiting to be found by those who earnestly seek Him, offering rest to all who are weary and burdened (Matthew 11:28-30).

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Commentary on Luke 2 verses 41–52

I. II. Main points1. 2. Sub-points

We have here the only passage of story recorded concerning our blessed Saviour, from his infancy to the day of his showing to Israel at twenty-nine years old, and therefore we are concerned to make much of this, for it is in vain to wish we had more. Here is,

I. Christ's going up with his parents to Jerusalem, at the feast of the passover, Luk 2:41, Luk 2:42. 1. It was their constant practice to attend there, according to the law, though it was a long journey, and they were poor, and perhaps not well able, without straitening themselves, to bear the expenses of it. Note, Public ordinances must be frequented, and we must not forsake the assembling of ourselves together, as the manner of some is. Worldly business must give way to spiritual concerns. Joseph and Mary had a son in the house with them, that was able to teach them better than all the rabbin at Jerusalem; yet they went up thither, after the custom of the feast. The Lord loves the gates of Zion more than all the dwellings of Jacob, and so should we. We have reason to suppose that Joseph went up likewise at the feasts of pentecost and tabernacles; for all the males were to appear there thrice a year, but Mary only at the passover, which was the greatest of the three feasts, and had most gospel in it. 2. The child Jesus, at twelve years old, went up with them. The Jewish doctors say that at twelve years old children must begin to fast from time to time, that they may learn to fast on the day of atonement; and that at thirteen years old a child begins to be a son of the commandment, that is, obliged to the duties of adult church-membership, having been from his infancy, by virtue of his circumcision, a son of the covenant. It is not said that this was the first time that Jesus went up to Jerusalem to worship at the feast: probably he had done it for some years before, having spirit and wisdom above his years; and all should attend on public worship that can hear with understanding, Neh 8:2. Those children that are forward in other things should be put forward in religion. It is for the honour of Christ that children should attend on public worship, and he is pleased with their hosannas; and those children that were in their infancy dedicated to God should be called upon, when they are grown up, to come to the gospel passover, to the Lord's supper, that they make it their own act and deed to join themselves to the Lord.

II. Christ's tarrying behind his parents at Jerusalem, unknown to them, in which he designed to give an early specimen of what he was reserved for.

1.His parents did not return till they had fulfilled the days; they had staid there all the seven days at the feast, though it was not absolutely necessary that they should stay longer than the two first days, after which many went home. Note, It is good to stay to the conclusion of an ordinance, as becomes those who say, It is good to be here, and not to hasten away, as if we were like Doeg, detained before the Lord.

2.The child tarried behind in Jerusalem, not because he was loth to go home, or shy of his parents' company, but because he had business to do there, and would let his parents know that he had a Father in heaven, whom he was to be observant of more than of them; and respect to him must not be construed disrespect to them. Some conjecture that he tarried behind in the temple, for it was the custom of the pious Jews, on the morning that they were to go home, to go first to the temple, to worship God; there he staid behind, and found entertainment there till they found him again. Or, perhaps, he staid at the house where they lodged, or some other friend's house (and such a child as he was could not but be the darling of all that knew him, and every one would court his company), and went up to the temple only at church-time; but so it was that he staid behind. It is good to see young people willing to dwell in the house of the Lord; they are then like Christ.

3.His parents went the first day's journey without any suspicion that he was left behind, for they supposed him to have been in the company, Luk 2:44. On these occasions, the crowd was very great, especially the first day's journey, and the roads full of people; and they concluded that he came along with some of their neighbours, and they sought him among their kindred and acquaintance, that were upon the road, going down. Pray did you see our Son? or, Did you see him? Like the spouses's inquiry, Saw ye him whom my soul loveth? This was a jewel worth seeking after. They knew that every one would be desirous of his company, and that he would be willing to do good among his kinsfolk and acquaintance, but among them they found him not, Luk 2:45. There are many, too many, who are our kinsfolk and acquaintance, that we cannot avoid conversing with, among whom we find little or nothing of Christ. When they could not hear of him in this and the other company upon the road, yet they hoped they should meet with him at the place where they lodged that night; but there they could learn no tidings of him. Compare this with Job 23:8, Job 23:9.

4.When they found him not at their quarters at night, they turned back again, next morning, to Jerusalem, seeking him. Note, Those that would find Christ must seek till they find; for he will at length be found of those that seek him, and will be found their bountiful rewarder. Those that have lost their comforts in Christ, and the evidences of their interest in him, must bethink themselves where, and when, and how, they lost them, and must turn back again to the place where they last had them; must remember whence they are fallen, and repent, and do their first works, and return to their first love, Rev 2:4, Rev 2:5. Those that would recover their lost acquaintance with Christ must go to Jerusalem, the city of our solemnities, the place which he has chosen to put his name there; must attend upon him in his ordinances, in the gospel-passover, there they may hope to meet him.

5.The third day they found him in the temple, in some of the apartments belonging to the temple, where the doctors of the law kept, not their courts, but their conferences rather, or their schools for disputation; and there they found him sitting in the midst of them (Luk 2:46), not standing as a catechumen to be examined or instructed by them, for he had discovered such measures of knowledge and wisdom that they admitted him to sit among them as a fellow or member of their society. This is an instance, not only that he was filled with wisdom (Luk 2:40), but that he had both a desire to increase it and a readiness to communicate it; and herein he is an example to children and young people, who should learn of Christ to delight in the company of those they may get good by, and choose to sit in the midst of the doctors rather than in the midst of the players. Let them begin at twelve years old, and sooner, to enquire after knowledge, and to associate with those that are able to instruct them; it is a hopeful and promising presage in youth to be desirous of instruction. Many a youth at Christ's age now would have been playing with the children in the temple, but he was sitting with the doctors in the temple. (1.) He heard them. Those that would learn must be swift to hear. (2.) He asked them questions; whether, as a teacher (he had authority so to ask) or as a learner (he had humility so to ask) I know not, or whether as an associate, or joint-searcher after truth, which must be found out by mutual amicable disquisitions. (3.) He returned answers to them, which were very surprising and satisfactory, Luk 2:47. And his wisdom and understanding appeared as much in the questions he asked as in the answers he gave, so that all who heard him were astonished: they never heard one so young, no indeed any of their greatest doctors, talk sense at the rate that he did; like David, he had more understanding than all his teachers, yea, than the ancients, Psa 119:99, Psa 119:100. Now Christ showed forth some rays of his glory, which were presently drawn in again. He gave them a taste (says Calvin) of his divine wisdom and knowledge. Methinks this public appearance of Christ in the temple, as a teacher, was like Moses's early attempt to deliver Israel, which Stephen put this construction upon, that he supposed his brethren would have understood, by that, how God by his hand would deliver them, Act 7:24, Act 7:25. They might have taken the hint, and been delivered then, but they understood not; so they here might have had Christ (for aught I know) to enter upon his work now, but they were only astonished, and understood not the indication; and therefore, like Moses, he retires into obscurity again, and they hear no more of him for many years after.

6.His mother talked with him privately about it. When the company broke up, she took him aside, and examined him about it with a deal of tenderness and affection, Luk 2:48. Joseph and Mary were both amazed to find him there, and to find that he had so much respect showed him as to be admitted to sit among the doctors, and to be taken notice of. His father knew he had only the name of a father, and therefore said nothing. But, (1.) His mother told him how ill they took it: "Son, why hast thou thus dealt with us? Why didst thou put us into such a fright?" They were ready to say, as Jacob of Joseph, "A wild beast has devoured him; or, He is fallen into the hands of some more cruel enemy, who has at length found out that he was the young child whose life Herod had sought some years ago." A thousand imaginations, we may suppose, they had concerning him, each more frightful than another. "Now, why hast thou given us occasion for these fears? Thy father and I have sought thee, sorrowing; not only troubled that we lost thee, but vexed at ourselves that we did not take more care of thee, to bring thee along with us." Note, Those may have leave to complain of their losses that think they have lost Christ. But their weeping did not hinder sowing; they did not sorrow and sit down in despair, but sorrowed and sought. Note, If we would find Christ, we must seek him sorrowing, sorrowing that we have lost him, that we have provoked him to withdraw, and that we have sought him no sooner. They that thus seek him in sorrow shall find him, at length, with so much the greater joy. (2.) He gently reproved their inordinate solicitude about him (Luk 2:49): "How is it that you sought me? You might have depended upon it, I would have followed you home when I had done the business I had to do here. I could not be lost in Jerusalem. Wist ye not that I ought to be, en tois tou patros mou; - in my Father's house?" so some read it; "where else should the Son be, who abideth in the house for ever? I ought to be," [1.] "Under my Father's care and protection; and therefore you should have cast the care of me upon him, and not have burdened yourselves with it." Christ is a shaft hid in his Father's quiver, Isa 49:2. He takes care of his church likewise, and therefore let us never despair of its safety. [2.] "At my Father's work" (so we take it): "I must be about my Father's business, and therefore could not go home as soon as you might. Wist ye not? Have you not already perceived that concerning me, that I have devoted myself to the service of religion, and therefore must employ myself in the affairs of it?" Herein he hath left us an example; for it becomes the children of God, in conformity to Christ, to attend their heavenly Father's business, and to make all other business give way to it. This word of Christ we now think we understand very well, for he hath explained it in what he hath done and said. It was his errand into the world, and his meat and drink in the world, to do his Father's will, and finish his work: and yet at that time his parents understood not this saying, Luk 2:50. They did not understand what business he had to do then in the temple for his Father. They believed him to be the Messiah, that should have the throne of his father David; but they thought that should rather bring him to the royal palace than to the temple. They understood not his prophetical office; and he was to do much of his work in that.

Lastly, Here is their return to Nazareth. This glimpse of his glory was to be short. It was now over, and he did not urge his parents either to come and settle at Jerusalem or to settle him there (though that was the place of improvement and preferment, and where he might have the best opportunities of showing his wisdom), but very willingly retired into his obscurity at Nazareth, where for many years he was, as it were, buried alive. Doubtless, he came up to Jerusalem, to worship at the feast, three times a year, but whether he ever went again into the temple, to dispute with the doctors there, we are not told; it is not improbable but he might. But here we are told,

1.That he was subject to his parents. Though once, to show that he was more than a man, he withdrew himself from his parents, to attend his heavenly Father's business, yet he did not, as yet, make that his constant practice, nor for many years after, but was subject to them, observed their order, and went and came as they directed, and, as it should seem, worked with his father at the trade of a carpenter. Herein he hath given an example to children to be dutiful and obedient to their parents in the Lord. Being made of a woman, he was made under the law of the fifth commandment, to teach the seed of the faithful thus to approve themselves to him a faithful seed. Though his parents were poor and mean, though his father was only his supposed father, yet he was subject to them; though he was strong in spirit, and filled with wisdom nay though he was the Son of God, yet he was subject to his parents; how then will they answer it who, though foolish and weak, yet are disobedient to their parents?

2.That his mother, though she did not perfectly understand her son's sayings, yet kept them in her heart, expecting that hereafter they would be explained to her, and she should fully understand them, and know how to make use of them. However we may neglect men's sayings because they are obscure (Si non vis intelligi debes negligi - If it be not intelligible, it is not valuable), yet we must not think so of God's sayings. That which at first is dark, so that we know not what to make of it, may afterwards become plain and easy; we should therefore lay it up for hereafter. See Joh 2:22. We may find use for that another time which now we see not how to make useful to us. A scholar keeps those grammar rules in memory which at present he understands not the use of, because he is told that they will hereafter be of use to him; so we must do by Christ's sayings.

3.That he improved, and came on, to admiration (Luk 2:52): He increased in wisdom and stature. In the perfections of his divine nature there could be no increase; but this is meant of his human nature, his body increased in stature and bulk, he grew in the growing age; and his soul increased in wisdom, and in all the endowments of a human soul. Though the Eternal Word was united to the human soul from his conception, yet the divinity that dwelt in him manifested itself to his humanity by degrees, ad modum recipientis - in proportion to his capacity; as the faculties of his human soul grew more and more capable, the gifts it received from the divine nature were more and more communicated. And he increased in favour with God and man, that is, in all those graces that rendered him acceptable to God and man. Herein Christ accommodated himself to his estate of humiliation, that, as he condescended to be an infant, a child, a youth, so the image of God shone brighter in him, when he grew up to be a youth, than it did, or could, while he was an infant and a child. Note, Young people, as they grow in stature, should grow in wisdom, and then, as they grow in wisdom, they will grow in favour with God and man.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 41–52. Public domain.
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Origen of Alexandria (as quoted by Aquinas, AD 1274)AD 253
Catena Aurea by Aquinas
He is not found as soon as sought for, for Jesus was not among His kinsfolk and relations, among those who are joined to Him in the flesh, nor in the company of the multitude can He be found. Learn where those who seek Him find Him, not every where, but in the temple. And do thou then seek Jesus in the temple of God. Seek Him in the Church, and seek Him among the masters who are in the temple. For if thou wilt so seek Him, thou shalt find Him. They found Him not among His kinsfolk, for human relations could not comprehend the Son of God; not among His acquaintance, for He passes far beyond all human knowledge and understanding. Where then do they find Him? In the temple! If at any time thou seek the Son of God, seek Him first in the temple, thither go up, and verily shalt thou find Christ, the Word, and the Wisdom, (i. e. the Son of God.)
Ambrose of Milan (as quoted by Aquinas, AD 1274)AD 397
Catena Aurea by Aquinas
Or the twelfth year was the commencement of our Lord's disputation with the doctors, for this was the number of the Evangelists necessary to preach the faith.

After three days He is found in the temple, that it might be for a sign, that after three days of victorious suffering, He who was believed to be dead should rise again, and manifest Himself to our faith, seated in heaven with divine glory.

There are two generations in Christ, one from His Father, the other from His mother; the Father's more divine, the mother's that which has come down for our use and advantage.
Epiphanius of Salamis (as quoted by Aquinas, AD 1274)AD 403
Catena Aurea by Aquinas
(cont. Hær. l. ii. hær. 31.) Let Ebion know that at twelve years old, not thirty, Christ is found the astonishment of all men, wonderful and mighty in the words of grace. We can not therefore say, that after that the Spirit came to Him in Baptism He was made the Christ, that is, anointed with divinity, but from His very childhood He acknowledged both the temple and His Father.
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
(sup. Joh. Hom. 20.) The Lord truly did no miracle in His childhood, yet this one fact St. Luke mentions, which made men look with wonder upon Him.
BedeAD 735
Homilies on the Gospels 1.19
The Lord’s coming every year to Jerusalem for the Passover with his parents is an indication of his human humility. It is characteristic of human beings to gather to offer God the votive offerings of spiritual sacrifices, and by plentiful prayers and tears to dispose their Maker toward them. Therefore the Lord, born a human being among human beings, did what God, by divine inspiration through his angels, prescribed for human beings to do. He himself kept the law which he gave in order to show us, who are human beings pure and simple, that whatever God orders is to be observed in everything. Let us follow the path of his human way of life. If we take delight in looking upon the glory of his divinity, if we want to dwell in his eternal home in heaven all the days of our lives, it delights us to see the Lord’s will and to be shielded by his holy temple. And lest we be forever buffeted by the wind of wickedness, let us remember to frequent the house, the church of the present time, with the requisite offerings of pure petitions.
Bede (as quoted by Aquinas, AD 1274)AD 735
Catena Aurea by Aquinas
We may also say, that as by the seventh number, so also by the twelfth, (which consists of the parts of seven multiplied alternately by one another,) the universality and perfection of either things or times is signified, and therefore rightly from the number twelve, the glory of Christ takes its beginning, being that by which all places and times are to be filled.

(in Hom. post Epiph.) Now that the Lord came up every year to Jerusalem at the Passover, betokens His humility as a man, for it is man's duty to meet together to offer sacrifices to God, and conciliate Him with prayers. Accordingly the Lord as man, did among men what God by angels commanded men to do. Hence it is said, According to the custom of the feast day. (Gal. 3:14, Judges 6:20; 13:16.) Let us follow then the journey of His mortal life, if we delight to behold the glory of His divine nature.

But some one will ask, how was it that the Son of God, brought up by His parents with such care, could be left behind from forgetfulness? To which it is answered, that the custom of the children of Israel while assembling at Jerusalem on the feast days, or returning to their homes, was for the women and men to go separately, and the infants or children to go with either parent indiscriminately. And so both Mary and Joseph each thought in turn that the Child Jesus, whom they saw not with them, was returning with the other parent. Hence it follows, But they, supposing him to have been in the company, &c.

To show that He was a man, He humbly listened to the masters; but to prove that He was God, He divinely answered those who spake.

For from His tongue there went forth divine wisdom, while His age exhibited man's helplessness, and hence the Jews, amid the high things they hear and the lowly things they see, are perplexed with doubts and astonishment. But we can in no wise wonder, knowing the words of the Prophet, that thus unto us a Child is born, that He abideth the mighty God. (Is. 9:6.)

He blames them not that they seek Him as their son, but compels them to raise the eyes of their mind to what was rather due to Him whose eternal Son He was. Hence it follows, Knew ye not? &c.

It follows, And they understood him not, that is, the word which He spoke to them of His divinity.
Ancient Greek Expositor (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(Geometer) His indication of wisdom did not exceed the measure of His age, but at the time that with us the powers of discernment are generally perfected, the wisdom of Christ shows itself.

(Metaphrastes vel Geometer.) The feast having been celebrated, while the rest returned, Jesus secretly tarried behind. As it follows, And when they had fulfilled the days, as they returned, the child Jesus tarried behind in Jerusalem; and his parents knew not of it. It is said, When the days were accomplished, because the feast lasted seven days. But the reason of His tarrying behind in secret was, that His parents might not be a hindrance to His carrying on the discussion with the lawyers; or perhaps to avoid appearing to despise his parents by not obeying their commands. He remains therefore secretly, that he might neither be kept away nor be disobedient.

(Metaphrastes vel Geometer.) He asks questions with reason, He listens with wisdom, and answers with more wisdom, so as to cause astonishment. As it follows, And they who saw it were astonished.

(ubi sup.) But the ever-wonderful mother of God, moved by a mother's feelings, as it were with weeping makes her mournful enquiry, in every thing like a mother, with confidence, humility, and affection. As it follows, And his mother said unto him, Son, what hast thou done?

(Metaphrastes et Geometer.) But the Lord Himself sets every thing at rest, and correcting as it were her saying concerning him who was His reputed father, manifests His true Father, teaching us not to walk on the ground, but to raise ourselves on high, as it follows, And he says unto them, What is it that you ask of me?

(Geometer.) This is the first demonstration of the wisdom and power of the Child Jesus. For as to what are called thea acts of His childhood, we can not but suppose them to be the work not only of a childish but even of a devilish mind and perverse will, attempting to revile those things which are contained in the Gospel and the sacred prophecies. But should one desire to receive only such things as are generally believed, and are not contrary to our other declarations, but accord also with the words of prophecy, let it suffice that Jesus was distinguished in form above the sons of men; obedient to His mother, gentle in disposition; in appearance full of grace and dignity; eloquent in words, kind and thoughtful of the wants of others, known among all for a power and energy, as of one who was filled with all wisdom; and as in other things, so also in all human conversation, though above man, Himself the rule and measure. But that which most distinguished Him was His meekness, and that a razor had never come upon His head, nor any human hand except His mother's. But from these words we may derive a lesson; for when the Lord reproves Mary seeking Him among His relations, He most aptly points to the giving up of all fleshly ties, showing that it is not for him to attain the goal of perfection who is still encompassed by and walks among the things of the body, and that men fall from perfection through love of their relations.
Glossa Ordinaria (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(ordin.) They were on their way home, one day's journey from Jerusalem; on the second day they seek for Him among their kinsfolk and acquaintance, and when they found Him not, they returned on the third day to Jerusalem, and there they found Him. As it follows, And it came to pass, after three days they found him.

(ubi sup.) Or because the advent of Christ, which was looked for by the Patriarchs before the Law, was not found, nor again, that which was sought for by prophets and just men under the Law, but that alone is found which is sought for by Gentiles under grace.

(ordin.) Or they feared lest Herod who sought Him in His infancy, now that He was advanced to boyhood might find an opportunity of putting Him to death.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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