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Translation
King James Version
And he said unto them, How is it that ye sought me? wist ye not that I must be about my Father's business?
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KJV (with Strong's)
And G2532 he said G2036 unto G4314 them G846, How G5101 is it that G3754 ye sought G2212 me G3165? wist ye G1492 not G3756 that G3754 I G3165 must G1163 be G1511 about G1722 my G3450 Father's business G3962?
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Complete Jewish Bible
He said to them, "Why did you have to look for me? Didn't you know that I had to be concerning myself with my Father's affairs?"
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Berean Standard Bible
“Why were you looking for Me?” He asked. “Did you not know that I had to be in My Father’s house?”
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American Standard Version
And he said unto them, How is it that ye sought me? knew ye not that I must be in my Father’s house?
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World English Bible Messianic
He said to them, “Why were you looking for me? Didn’t you know that I must be in my Father’s house?”
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Geneva Bible (1599)
Then said he vnto them, Howe is it that ye sought me? knewe ye not that I must goe about my Fathers busines?
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Young's Literal Translation
And he said unto them, `Why is it that ye were seeking me? did ye not know that in the things of my Father it behoveth me to be?'
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SUMMARY

Luke 2:49 records the inaugural spoken words of Jesus Christ in the New Testament, offering a profound glimpse into His self-awareness, divine identity, and singular mission even at the tender age of twelve. Discovered by His distraught parents, Mary and Joseph, after a three-day search following their Passover pilgrimage, Jesus responds not with an apology for their distress but with a question that clarifies His unique relationship with God and His unwavering commitment to His heavenly Father's purpose. This pivotal declaration foreshadows His entire earthly ministry and ultimate redemptive work.

CONTEXT

  • Literary Context: This verse is situated within the narrative of Jesus' childhood, specifically following the annual Passover pilgrimage to Jerusalem (Luke 2:41-42). After the feast, Mary and Joseph departed, assuming Jesus was among their traveling companions, a common practice in large groups. When they discovered His absence, they returned to Jerusalem, frantically searching for three days (Luke 2:43-45). Their search culminates in the Temple courts, where they find Jesus not lost or distressed, but engaged in deep discussion with the religious teachers, "both hearing them, and asking them questions" (Luke 2:46). His profound understanding and answers astonished all who heard Him (Luke 2:47). Mary's understandable expression of concern and gentle rebuke in Luke 2:48 sets the stage for Jesus' revelatory response in verse 49, marking it as a crucial turning point in the narrative of His early life.
  • Historical & Cultural Context: The annual Passover pilgrimage to Jerusalem was a central religious obligation for Jewish families, commemorating the Exodus from Egypt. Traveling in large caravans provided a sense of security and community, making it plausible for parents to assume a child was with other relatives or friends. The Temple in Jerusalem was not merely a place of worship but also a center of religious learning and legal discourse, where rabbis and scribes would teach and debate. For a twelve-year-old boy, the age at which Jewish males were considered sons of the law (though the Bar Mitzvah ceremony as we know it developed later, the concept of increased responsibility and engagement with the Torah was present), to be found in such a setting, engaging with learned teachers, was highly unusual and indicative of extraordinary precocity. Jesus' presence and engagement underscore the deep spiritual and intellectual environment of the Temple and His unique connection to it.
  • Key Themes: This verse contributes significantly to several major themes in Luke's Gospel and the broader biblical narrative. It powerfully establishes Jesus' Divine Awareness and unique Sonship, as He explicitly refers to God as "my Father," distinguishing His relationship from that of ordinary humans. This early declaration sets the stage for His later ministry, where His identity as the Son of God is central. Furthermore, the passage highlights the Priority of God's Will in Jesus' life; even as a child, His primary allegiance was to His heavenly Father's purpose, not the immediate concerns of His earthly family. This theme of obedience to the Father's will permeates His entire life, culminating in His submission to the cross, as seen in passages like John 4:34 where He declares His food is to do the will of Him who sent Him. Finally, the account underscores Jesus' Exceptional Wisdom and Understanding, foreshadowing His growth in "wisdom and stature, and in favour with God and man" (as noted in Luke 2:52). His ability to engage with and astonish the teachers (Luke 2:47) points to His divine knowledge and insight, which would later be fully revealed in His public ministry.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • wist (Greek, eídō', G1492): (eídō), a primary verb meaning "to see (literally or figuratively); by implication, (in the perfect tense only) to know." In this context, it carries the sense of "did you not know" or "were you not aware." Jesus' question implies that His parents, especially Mary who had received angelic revelations, should have had an understanding of His unique identity and divine purpose, which would naturally lead Him to be engaged in God's affairs.
  • must (Greek, deî', G1163): (deî), used impersonally, meaning "it is (was, etc.) necessary (as binding)." This word conveys a strong sense of divine compulsion, obligation, or destiny. Jesus' use of "must" indicates that His actions were not arbitrary but were driven by a profound, inherent necessity rooted in His divine nature and mission. It highlights His pre-ordained path and His unwavering commitment to fulfilling it.
  • Father's (Greek, patḗr', G3962): (patḗr), meaning "a 'father' (literally or figuratively, near or more remote)." Here, Jesus uses "my Father" (with G3450, moû, "my") to refer to God. This is a crucial and revelatory statement, asserting a unique, intimate, and authoritative relationship with God that transcends ordinary human sonship. It is the earliest recorded instance of Jesus explicitly claiming this divine paternity, setting Him apart as the Son of God.

Verse Breakdown

  • "And he said unto them": This simple introductory clause establishes the speaker as Jesus and the audience as Mary and Joseph, setting the stage for His profound declaration. It highlights the directness of His response to their expressed concern.
  • "How is it that ye sought me?": This is a rhetorical question that expresses Jesus' mild astonishment or perhaps a gentle rebuke. It implies that His parents' search was unnecessary or misplaced, given His inherent nature and purpose. He is questioning their lack of understanding about where He truly belonged and what He was compelled to do.
  • "wist ye not that I must be about my Father's business?": This is the core of Jesus' statement, revealing His profound self-awareness. "Wist ye not" (did you not know?) directly challenges their perception. The phrase "about my Father's business" translates the Greek en tois tou patros mou (ἐν τοῖς τοῦ πατρός μου), which literally means "in the things of my Father" or "in my Father's house." This encompasses both the physical location (the Temple, as God's house) and, more profoundly, His divine work, mission, and the affairs pertaining to His heavenly Father's will. Jesus was not merely in a place; He was engaged in His very purpose.

Literary Devices

Luke 2:49 masterfully employs several literary devices to convey its profound theological meaning. The most prominent is Rhetorical Question, as Jesus asks, "How is it that ye sought me? wist ye not that I must be about my Father's business?" These questions are not posed to elicit information but to make a forceful point and highlight the parents' lack of comprehension regarding His divine nature and mission. This serves to underscore Jesus' unique identity. The verse also utilizes Foreshadowing, as Jesus' early declaration of being "about my Father's business" powerfully anticipates His entire earthly ministry, which was singularly devoted to fulfilling the Father's will, culminating in His atoning death and resurrection. Finally, there is a subtle Irony in the scene: Mary and Joseph were frantically searching for Jesus, believing Him to be lost, yet He was precisely where He was meant to be, engaged in the most important "business" of His life, fulfilling His divine calling in the very house of His Father.

THEOLOGICAL AND THEMATIC CONNECTIONS

Luke 2:49 stands as a foundational theological statement, revealing Jesus' unique consciousness of His divine Sonship and His unwavering commitment to His redemptive mission from an astonishingly young age. It establishes that Jesus' identity is inextricably linked to His heavenly Father, and His life's purpose is to fulfill the Father's will. This early declaration sets the trajectory for His entire ministry, demonstrating that His actions were always rooted in divine necessity and obedience, not human whim or earthly ambition. It highlights the profound mystery of the Incarnation—that the Son of God, though fully human, possessed a divine awareness and purpose from His earliest days. This verse is a powerful testament to Jesus' pre-existent relationship with the Father and His pre-ordained role in salvation history.

REFLECTION AND APPLICATION

Luke 2:49 offers a profound challenge and inspiration for believers today. Jesus' singular focus on "His Father's business" from such a young age calls us to examine our own priorities and allegiances. Are we, like Jesus, primarily concerned with the will and work of our heavenly Father, or are we easily distracted by earthly concerns and personal ambitions? This verse encourages us to actively seek and discern God's purpose for our lives, understanding that our ultimate calling is to glorify Him and participate in His kingdom work. It reminds us that true fulfillment comes not from pursuing our own agendas, but from aligning our lives with God's eternal plan. Just as Jesus grew in wisdom and understanding, we too are called to continually deepen our knowledge of God's Word and His character, allowing His truth to shape our thoughts and actions. This passage serves as a timeless reminder that our spiritual responsibilities and divine calling should always take precedence, guiding our decisions and shaping our very existence.

Questions for Reflection

  • What does "my Father's business" mean for my life today, and how can I actively pursue it?
  • In what areas of my life do I tend to prioritize earthly concerns over spiritual ones, and how can I re-align my focus?
  • How can I cultivate a deeper awareness of God's presence and purpose, similar to Jesus' innate understanding?
  • What steps can I take to grow in wisdom and understanding of God's Word and His will, as Jesus did?

FAQ

What is the significance of Jesus' age (12) in this account?

Answer: Jesus' age of twelve is highly significant within Jewish culture, though it predates the formal Bar Mitzvah ceremony as we know it today. At this age, a Jewish boy was traditionally considered to be transitioning into adulthood, becoming a "son of the commandment" (bar mitzvah), and thus more responsible for observing the Mosaic Law. This meant a greater engagement with religious instruction and community life. For Jesus to be found in the Temple, engaging with learned teachers, demonstrates an unparalleled spiritual maturity and intellectual capacity far beyond His years, signaling His unique identity and divine calling. It's His public debut, revealing His extraordinary nature before His formal ministry began.

What does "Father's business" truly encompass?

Answer: The phrase "my Father's business" (Greek: en tois tou patros mou) literally means "in the things of my Father" or "in my Father's house." While it certainly includes the physical location of the Temple, which was considered God's house, its meaning is far broader and more profound. It encompasses Jesus' entire divine mission and purpose on earth, which was to reveal God, to do God's will, and ultimately to accomplish the work of redemption. This includes His teaching, healing, demonstrating God's kingdom, and ultimately His suffering, death, and resurrection. It signifies His absolute dedication to fulfilling the redemptive plan that the Father had set for Him, as seen throughout His later ministry, where He consistently stated His purpose was to do the will of the One who sent Him (e.g., John 6:38).

CHRIST-CENTERED FULFILLMENT

Luke 2:49 is a profound Christ-centered declaration, serving as the earliest recorded verbal testament to Jesus' unique divine identity and the singular purpose that would define His entire life and ministry. His statement, "I must be about my Father's business," is not merely a child's precocious insight but a foundational truth revealing the very essence of the Incarnation. It foreshadows the unwavering obedience of the Son to the Father's will, a commitment that would lead Him from the Temple courts to the cross. This "business" was the grand plan of salvation, the very reason the Word became flesh and dwelt among us. Every miracle, every sermon, every act of compassion, and ultimately His atoning sacrifice on Calvary, was part of this divine "business" to reconcile humanity to God. He came not to do His own will, but the will of Him who sent Him, as He later affirmed in John 6:38. This early glimpse into Jesus' consciousness underscores that His entire life was a seamless fulfillment of the Father's redemptive purpose, culminating in His resurrection and ascension, thereby accomplishing the ultimate "business" of securing eternal life for all who believe in Him, the Lamb of God who takes away the sin of the world.

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Commentary on Luke 2 verses 41–52

I. II. Main points1. 2. Sub-points

We have here the only passage of story recorded concerning our blessed Saviour, from his infancy to the day of his showing to Israel at twenty-nine years old, and therefore we are concerned to make much of this, for it is in vain to wish we had more. Here is,

I. Christ's going up with his parents to Jerusalem, at the feast of the passover, Luk 2:41, Luk 2:42. 1. It was their constant practice to attend there, according to the law, though it was a long journey, and they were poor, and perhaps not well able, without straitening themselves, to bear the expenses of it. Note, Public ordinances must be frequented, and we must not forsake the assembling of ourselves together, as the manner of some is. Worldly business must give way to spiritual concerns. Joseph and Mary had a son in the house with them, that was able to teach them better than all the rabbin at Jerusalem; yet they went up thither, after the custom of the feast. The Lord loves the gates of Zion more than all the dwellings of Jacob, and so should we. We have reason to suppose that Joseph went up likewise at the feasts of pentecost and tabernacles; for all the males were to appear there thrice a year, but Mary only at the passover, which was the greatest of the three feasts, and had most gospel in it. 2. The child Jesus, at twelve years old, went up with them. The Jewish doctors say that at twelve years old children must begin to fast from time to time, that they may learn to fast on the day of atonement; and that at thirteen years old a child begins to be a son of the commandment, that is, obliged to the duties of adult church-membership, having been from his infancy, by virtue of his circumcision, a son of the covenant. It is not said that this was the first time that Jesus went up to Jerusalem to worship at the feast: probably he had done it for some years before, having spirit and wisdom above his years; and all should attend on public worship that can hear with understanding, Neh 8:2. Those children that are forward in other things should be put forward in religion. It is for the honour of Christ that children should attend on public worship, and he is pleased with their hosannas; and those children that were in their infancy dedicated to God should be called upon, when they are grown up, to come to the gospel passover, to the Lord's supper, that they make it their own act and deed to join themselves to the Lord.

II. Christ's tarrying behind his parents at Jerusalem, unknown to them, in which he designed to give an early specimen of what he was reserved for.

1.His parents did not return till they had fulfilled the days; they had staid there all the seven days at the feast, though it was not absolutely necessary that they should stay longer than the two first days, after which many went home. Note, It is good to stay to the conclusion of an ordinance, as becomes those who say, It is good to be here, and not to hasten away, as if we were like Doeg, detained before the Lord.

2.The child tarried behind in Jerusalem, not because he was loth to go home, or shy of his parents' company, but because he had business to do there, and would let his parents know that he had a Father in heaven, whom he was to be observant of more than of them; and respect to him must not be construed disrespect to them. Some conjecture that he tarried behind in the temple, for it was the custom of the pious Jews, on the morning that they were to go home, to go first to the temple, to worship God; there he staid behind, and found entertainment there till they found him again. Or, perhaps, he staid at the house where they lodged, or some other friend's house (and such a child as he was could not but be the darling of all that knew him, and every one would court his company), and went up to the temple only at church-time; but so it was that he staid behind. It is good to see young people willing to dwell in the house of the Lord; they are then like Christ.

3.His parents went the first day's journey without any suspicion that he was left behind, for they supposed him to have been in the company, Luk 2:44. On these occasions, the crowd was very great, especially the first day's journey, and the roads full of people; and they concluded that he came along with some of their neighbours, and they sought him among their kindred and acquaintance, that were upon the road, going down. Pray did you see our Son? or, Did you see him? Like the spouses's inquiry, Saw ye him whom my soul loveth? This was a jewel worth seeking after. They knew that every one would be desirous of his company, and that he would be willing to do good among his kinsfolk and acquaintance, but among them they found him not, Luk 2:45. There are many, too many, who are our kinsfolk and acquaintance, that we cannot avoid conversing with, among whom we find little or nothing of Christ. When they could not hear of him in this and the other company upon the road, yet they hoped they should meet with him at the place where they lodged that night; but there they could learn no tidings of him. Compare this with Job 23:8, Job 23:9.

4.When they found him not at their quarters at night, they turned back again, next morning, to Jerusalem, seeking him. Note, Those that would find Christ must seek till they find; for he will at length be found of those that seek him, and will be found their bountiful rewarder. Those that have lost their comforts in Christ, and the evidences of their interest in him, must bethink themselves where, and when, and how, they lost them, and must turn back again to the place where they last had them; must remember whence they are fallen, and repent, and do their first works, and return to their first love, Rev 2:4, Rev 2:5. Those that would recover their lost acquaintance with Christ must go to Jerusalem, the city of our solemnities, the place which he has chosen to put his name there; must attend upon him in his ordinances, in the gospel-passover, there they may hope to meet him.

5.The third day they found him in the temple, in some of the apartments belonging to the temple, where the doctors of the law kept, not their courts, but their conferences rather, or their schools for disputation; and there they found him sitting in the midst of them (Luk 2:46), not standing as a catechumen to be examined or instructed by them, for he had discovered such measures of knowledge and wisdom that they admitted him to sit among them as a fellow or member of their society. This is an instance, not only that he was filled with wisdom (Luk 2:40), but that he had both a desire to increase it and a readiness to communicate it; and herein he is an example to children and young people, who should learn of Christ to delight in the company of those they may get good by, and choose to sit in the midst of the doctors rather than in the midst of the players. Let them begin at twelve years old, and sooner, to enquire after knowledge, and to associate with those that are able to instruct them; it is a hopeful and promising presage in youth to be desirous of instruction. Many a youth at Christ's age now would have been playing with the children in the temple, but he was sitting with the doctors in the temple. (1.) He heard them. Those that would learn must be swift to hear. (2.) He asked them questions; whether, as a teacher (he had authority so to ask) or as a learner (he had humility so to ask) I know not, or whether as an associate, or joint-searcher after truth, which must be found out by mutual amicable disquisitions. (3.) He returned answers to them, which were very surprising and satisfactory, Luk 2:47. And his wisdom and understanding appeared as much in the questions he asked as in the answers he gave, so that all who heard him were astonished: they never heard one so young, no indeed any of their greatest doctors, talk sense at the rate that he did; like David, he had more understanding than all his teachers, yea, than the ancients, Psa 119:99, Psa 119:100. Now Christ showed forth some rays of his glory, which were presently drawn in again. He gave them a taste (says Calvin) of his divine wisdom and knowledge. Methinks this public appearance of Christ in the temple, as a teacher, was like Moses's early attempt to deliver Israel, which Stephen put this construction upon, that he supposed his brethren would have understood, by that, how God by his hand would deliver them, Act 7:24, Act 7:25. They might have taken the hint, and been delivered then, but they understood not; so they here might have had Christ (for aught I know) to enter upon his work now, but they were only astonished, and understood not the indication; and therefore, like Moses, he retires into obscurity again, and they hear no more of him for many years after.

6.His mother talked with him privately about it. When the company broke up, she took him aside, and examined him about it with a deal of tenderness and affection, Luk 2:48. Joseph and Mary were both amazed to find him there, and to find that he had so much respect showed him as to be admitted to sit among the doctors, and to be taken notice of. His father knew he had only the name of a father, and therefore said nothing. But, (1.) His mother told him how ill they took it: "Son, why hast thou thus dealt with us? Why didst thou put us into such a fright?" They were ready to say, as Jacob of Joseph, "A wild beast has devoured him; or, He is fallen into the hands of some more cruel enemy, who has at length found out that he was the young child whose life Herod had sought some years ago." A thousand imaginations, we may suppose, they had concerning him, each more frightful than another. "Now, why hast thou given us occasion for these fears? Thy father and I have sought thee, sorrowing; not only troubled that we lost thee, but vexed at ourselves that we did not take more care of thee, to bring thee along with us." Note, Those may have leave to complain of their losses that think they have lost Christ. But their weeping did not hinder sowing; they did not sorrow and sit down in despair, but sorrowed and sought. Note, If we would find Christ, we must seek him sorrowing, sorrowing that we have lost him, that we have provoked him to withdraw, and that we have sought him no sooner. They that thus seek him in sorrow shall find him, at length, with so much the greater joy. (2.) He gently reproved their inordinate solicitude about him (Luk 2:49): "How is it that you sought me? You might have depended upon it, I would have followed you home when I had done the business I had to do here. I could not be lost in Jerusalem. Wist ye not that I ought to be, en tois tou patros mou; - in my Father's house?" so some read it; "where else should the Son be, who abideth in the house for ever? I ought to be," [1.] "Under my Father's care and protection; and therefore you should have cast the care of me upon him, and not have burdened yourselves with it." Christ is a shaft hid in his Father's quiver, Isa 49:2. He takes care of his church likewise, and therefore let us never despair of its safety. [2.] "At my Father's work" (so we take it): "I must be about my Father's business, and therefore could not go home as soon as you might. Wist ye not? Have you not already perceived that concerning me, that I have devoted myself to the service of religion, and therefore must employ myself in the affairs of it?" Herein he hath left us an example; for it becomes the children of God, in conformity to Christ, to attend their heavenly Father's business, and to make all other business give way to it. This word of Christ we now think we understand very well, for he hath explained it in what he hath done and said. It was his errand into the world, and his meat and drink in the world, to do his Father's will, and finish his work: and yet at that time his parents understood not this saying, Luk 2:50. They did not understand what business he had to do then in the temple for his Father. They believed him to be the Messiah, that should have the throne of his father David; but they thought that should rather bring him to the royal palace than to the temple. They understood not his prophetical office; and he was to do much of his work in that.

Lastly, Here is their return to Nazareth. This glimpse of his glory was to be short. It was now over, and he did not urge his parents either to come and settle at Jerusalem or to settle him there (though that was the place of improvement and preferment, and where he might have the best opportunities of showing his wisdom), but very willingly retired into his obscurity at Nazareth, where for many years he was, as it were, buried alive. Doubtless, he came up to Jerusalem, to worship at the feast, three times a year, but whether he ever went again into the temple, to dispute with the doctors there, we are not told; it is not improbable but he might. But here we are told,

1.That he was subject to his parents. Though once, to show that he was more than a man, he withdrew himself from his parents, to attend his heavenly Father's business, yet he did not, as yet, make that his constant practice, nor for many years after, but was subject to them, observed their order, and went and came as they directed, and, as it should seem, worked with his father at the trade of a carpenter. Herein he hath given an example to children to be dutiful and obedient to their parents in the Lord. Being made of a woman, he was made under the law of the fifth commandment, to teach the seed of the faithful thus to approve themselves to him a faithful seed. Though his parents were poor and mean, though his father was only his supposed father, yet he was subject to them; though he was strong in spirit, and filled with wisdom nay though he was the Son of God, yet he was subject to his parents; how then will they answer it who, though foolish and weak, yet are disobedient to their parents?

2.That his mother, though she did not perfectly understand her son's sayings, yet kept them in her heart, expecting that hereafter they would be explained to her, and she should fully understand them, and know how to make use of them. However we may neglect men's sayings because they are obscure (Si non vis intelligi debes negligi - If it be not intelligible, it is not valuable), yet we must not think so of God's sayings. That which at first is dark, so that we know not what to make of it, may afterwards become plain and easy; we should therefore lay it up for hereafter. See Joh 2:22. We may find use for that another time which now we see not how to make useful to us. A scholar keeps those grammar rules in memory which at present he understands not the use of, because he is told that they will hereafter be of use to him; so we must do by Christ's sayings.

3.That he improved, and came on, to admiration (Luk 2:52): He increased in wisdom and stature. In the perfections of his divine nature there could be no increase; but this is meant of his human nature, his body increased in stature and bulk, he grew in the growing age; and his soul increased in wisdom, and in all the endowments of a human soul. Though the Eternal Word was united to the human soul from his conception, yet the divinity that dwelt in him manifested itself to his humanity by degrees, ad modum recipientis - in proportion to his capacity; as the faculties of his human soul grew more and more capable, the gifts it received from the divine nature were more and more communicated. And he increased in favour with God and man, that is, in all those graces that rendered him acceptable to God and man. Herein Christ accommodated himself to his estate of humiliation, that, as he condescended to be an infant, a child, a youth, so the image of God shone brighter in him, when he grew up to be a youth, than it did, or could, while he was an infant and a child. Note, Young people, as they grow in stature, should grow in wisdom, and then, as they grow in wisdom, they will grow in favour with God and man.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 41–52. Public domain.
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IrenaeusAD 202
Against Heresies Book I
Some passages, also, which occur in the Gospels, receive from them a colouring of the same kind, such as the answer which He gave His mother when He was twelve years of age: "Wist ye not that I must be about My Father's business? "
TertullianAD 220
Against Praxeas
This He Himself, in those other Gospels also, testifies Himself to have been from His very boyhood: "Wist ye not," says He, "that I must be about my Father's business? " Satan likewise knew Him to be this in his temptations: "Since Thou art the Son of God.
Origen of Alexandria (as quoted by Aquinas, AD 1274)AD 253
Catena Aurea by Aquinas
The holy Virgin knew that He was not the Son of Joseph, and yet calls her husband His father according to the belief of the Jews, who thought that He was conceived in the common way. Now to speak generally we may say, that the Holy Spirit honoured Joseph by the name of father, because he brought up the Child Jesus; but more technically, that it might not seem superfluous in St. Luke, bringing down the genealogy from David to Joseph. But why sought they Him sorrowing? Was it that he might have perished or been lost? It could not be. For what should cause them to dread the loss of Him whom they knew to be the Lord? But as whenever you read the Scriptures you search out their meaning with pains, not that you suppose them to have erred or to contain anything incorrect, but that the truth which they have inherent in them you are anxious to find out; so they sought Jesus, lest perchance leaving them he should have returned to heaven, thither to descend when He would. He then who seeks Jesus must go about it not carelessly and idly, as many seek Him who never find Him, but with labour and sorrow.

Or they knew not whether when He said about my Father's business, He referred to the temple, or something higher and more edifying; for every one of us who doeth good, is the seat of God the Father; but whoso is the seat of God the Father, has Christ in the midst of him.
Origen of AlexandriaAD 253
HOMILIES ON THE GOSPEL OF LUKE 18.5
Surely Jesus was in the temple that Solomon had built. He confesses that it is the temple of his Father, whom he revealed to us, and whose Son he said he was.
Ephrem the SyrianAD 373
COMMENTARY ON TATIAN’S DIATESSARON 2.7
If, from the fact that some are called brothers of our Lord, people think that these are sons of Mary, take note that he was called son of Joseph. Not only did Jews call him the son of Joseph, but also Mary called him Joseph’s son. For “I and your father have been seeking you with much anxiety.” If the angel commanded Joseph to take Mary into his care, this was to eliminate any suspicion from her slanderers, and especially so that he might protect her in case those who were scandalized in thinking that it was from the angel that she was pregnant might kill her. It was a great source of scandal to them that a virgin should give birth, because they were convinced that through her giving birth their city would be destroyed and that their kingdom, priesthood and prophecy would be abolished. It was for this reason too that they also killed the prophet Isaiah who announced these things, that a virgin would give birth to a child.
Ambrose of Milan (as quoted by Aquinas, AD 1274)AD 397
Catena Aurea by Aquinas
Or the twelfth year was the commencement of our Lord's disputation with the doctors, for this was the number of the Evangelists necessary to preach the faith.

After three days He is found in the temple, that it might be for a sign, that after three days of victorious suffering, He who was believed to be dead should rise again, and manifest Himself to our faith, seated in heaven with divine glory.

There are two generations in Christ, one from His Father, the other from His mother; the Father's more divine, the mother's that which has come down for our use and advantage.
Ambrose of MilanAD 397
EXPOSITION OF THE GOSPEL OF LUKE 2.63
In the twelfth year, as we read, the beginning of the Lord's discussion is taken; for here the number of evangelizers who were to preach the faith was owed. Nor is it unimportant that, mindful of his earthly parents, who were certainly filled with the wisdom and grace of God according to the flesh, he is found in the temple after three days; so that he might provide evidence that after three days of his triumphant passion on the heavenly throne, and with divine honor, he would offer himself as resurrected for our faith, who was believed to be dead.
Epiphanius of Salamis (as quoted by Aquinas, AD 1274)AD 403
Catena Aurea by Aquinas
(cont. Hær. l. ii. hær. 31.) Let Ebion know that at twelve years old, not thirty, Christ is found the astonishment of all men, wonderful and mighty in the words of grace. We can not therefore say, that after that the Spirit came to Him in Baptism He was made the Christ, that is, anointed with divinity, but from His very childhood He acknowledged both the temple and His Father.
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
(sup. Joh. Hom. 20.) The Lord truly did no miracle in His childhood, yet this one fact St. Luke mentions, which made men look with wonder upon Him.
Cyril of AlexandriaAD 444
Commentary on the Gospel of Luke, Sermon V
Here then first He makes more open mention of Him Who is truly His Father, and lays bare His own divinity: for when the holy Virgin said, Child, why hast Thou so done unto us? then at once shewing Himself to transcend the measure of human things, and teaching her that she had been made the handmaid of the dispensation in giving birth to the flesh, but that He by nature and in truth was God, and the Son of the Father That is in heaven, He says, Did ye not know that I must be at My Father's? Here let the Valentinians, when they hear that the temple was God's, and that Christ was now at His own, Who long before also was so described in the law, and represented as in shadows and types, feel shame in affirming, that neither the Maker of the world, nor the God of the law, nor the God of the temple, was the Father of Christ.
Cyril of Alexandria (as quoted by Aquinas, AD 1274)AD 444
Catena Aurea by Aquinas
He says this then by way of showing that He surpasses all human standards, and hinting that the Holy Virgin was made the handmaid of the work in bringing His flesh unto the world, but that He Himself was by nature and in truth God, and the Son of the Father most high. Now from this let the followers of Valentinus, hearing that the temple was of God, be ashamed to say that the Creator, and the God of the law and of the temple, is not also the Father of Christ.
BedeAD 735
Homilies on the Gospels 1.19
Clearly the abode in the hearts of the elect of the holy Trinity, the nature of whose divinity is one and indivisible, cannot be disparate. Therefore, when he was sitting in the temple, the Lord said, “I must be about my Father’s business,” and this is a declaration of his power and glory which are co-eternal with God the Father’s. However, when he returned to Nazareth, he was subject to his parents, and this is an indication of his true humanity as well as an example of humility. He was subject to human beings in that human nature in which he is less than the Father. Hence he himself said, “I go to the Father because the Father is greater than I.” In that human nature, he was made a little less than the angels. In that other nature, however, in which he and the Father are one, and in virtue of which he does not go to the Father only now and then but is always in him, all things were made through him, and he is before all things.
Bede (as quoted by Aquinas, AD 1274)AD 735
Catena Aurea by Aquinas
We may also say, that as by the seventh number, so also by the twelfth, (which consists of the parts of seven multiplied alternately by one another,) the universality and perfection of either things or times is signified, and therefore rightly from the number twelve, the glory of Christ takes its beginning, being that by which all places and times are to be filled.

(in Hom. post Epiph.) Now that the Lord came up every year to Jerusalem at the Passover, betokens His humility as a man, for it is man's duty to meet together to offer sacrifices to God, and conciliate Him with prayers. Accordingly the Lord as man, did among men what God by angels commanded men to do. Hence it is said, According to the custom of the feast day. (Gal. 3:14, Judges 6:20; 13:16.) Let us follow then the journey of His mortal life, if we delight to behold the glory of His divine nature.

But some one will ask, how was it that the Son of God, brought up by His parents with such care, could be left behind from forgetfulness? To which it is answered, that the custom of the children of Israel while assembling at Jerusalem on the feast days, or returning to their homes, was for the women and men to go separately, and the infants or children to go with either parent indiscriminately. And so both Mary and Joseph each thought in turn that the Child Jesus, whom they saw not with them, was returning with the other parent. Hence it follows, But they, supposing him to have been in the company, &c.

To show that He was a man, He humbly listened to the masters; but to prove that He was God, He divinely answered those who spake.

For from His tongue there went forth divine wisdom, while His age exhibited man's helplessness, and hence the Jews, amid the high things they hear and the lowly things they see, are perplexed with doubts and astonishment. But we can in no wise wonder, knowing the words of the Prophet, that thus unto us a Child is born, that He abideth the mighty God. (Is. 9:6.)

He blames them not that they seek Him as their son, but compels them to raise the eyes of their mind to what was rather due to Him whose eternal Son He was. Hence it follows, Knew ye not? &c.

It follows, And they understood him not, that is, the word which He spoke to them of His divinity.
Ancient Greek Expositor (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(Geometer) His indication of wisdom did not exceed the measure of His age, but at the time that with us the powers of discernment are generally perfected, the wisdom of Christ shows itself.

(Metaphrastes vel Geometer.) The feast having been celebrated, while the rest returned, Jesus secretly tarried behind. As it follows, And when they had fulfilled the days, as they returned, the child Jesus tarried behind in Jerusalem; and his parents knew not of it. It is said, When the days were accomplished, because the feast lasted seven days. But the reason of His tarrying behind in secret was, that His parents might not be a hindrance to His carrying on the discussion with the lawyers; or perhaps to avoid appearing to despise his parents by not obeying their commands. He remains therefore secretly, that he might neither be kept away nor be disobedient.

(Metaphrastes vel Geometer.) He asks questions with reason, He listens with wisdom, and answers with more wisdom, so as to cause astonishment. As it follows, And they who saw it were astonished.

(ubi sup.) But the ever-wonderful mother of God, moved by a mother's feelings, as it were with weeping makes her mournful enquiry, in every thing like a mother, with confidence, humility, and affection. As it follows, And his mother said unto him, Son, what hast thou done?

(Metaphrastes et Geometer.) But the Lord Himself sets every thing at rest, and correcting as it were her saying concerning him who was His reputed father, manifests His true Father, teaching us not to walk on the ground, but to raise ourselves on high, as it follows, And he says unto them, What is it that you ask of me?

(Geometer.) This is the first demonstration of the wisdom and power of the Child Jesus. For as to what are called thea acts of His childhood, we can not but suppose them to be the work not only of a childish but even of a devilish mind and perverse will, attempting to revile those things which are contained in the Gospel and the sacred prophecies. But should one desire to receive only such things as are generally believed, and are not contrary to our other declarations, but accord also with the words of prophecy, let it suffice that Jesus was distinguished in form above the sons of men; obedient to His mother, gentle in disposition; in appearance full of grace and dignity; eloquent in words, kind and thoughtful of the wants of others, known among all for a power and energy, as of one who was filled with all wisdom; and as in other things, so also in all human conversation, though above man, Himself the rule and measure. But that which most distinguished Him was His meekness, and that a razor had never come upon His head, nor any human hand except His mother's. But from these words we may derive a lesson; for when the Lord reproves Mary seeking Him among His relations, He most aptly points to the giving up of all fleshly ties, showing that it is not for him to attain the goal of perfection who is still encompassed by and walks among the things of the body, and that men fall from perfection through love of their relations.
Glossa Ordinaria (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(ordin.) They were on their way home, one day's journey from Jerusalem; on the second day they seek for Him among their kinsfolk and acquaintance, and when they found Him not, they returned on the third day to Jerusalem, and there they found Him. As it follows, And it came to pass, after three days they found him.

(ubi sup.) Or because the advent of Christ, which was looked for by the Patriarchs before the Law, was not found, nor again, that which was sought for by prophets and just men under the Law, but that alone is found which is sought for by Gentiles under grace.

(ordin.) Or they feared lest Herod who sought Him in His infancy, now that He was advanced to boyhood might find an opportunity of putting Him to death.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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