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Genesis 6:1

“The Corruption of Mankind”· Genesis 6:1–4Read in context
King James Version
¶ And it came to pass, when men began to multiply on the face of the earth, and daughters were born unto them,
KJV (with Strong's)
And it came to pass, when men H120 began H2490 to multiply H7231 on H5921 the face H6440 of the earth H127, and daughters H1323 were born H3205 unto them,
Complete Jewish Bible
In time, when men began to multiply on earth, and daughters were born to them,
Berean Standard Bible
Now when men began to multiply on the face of the earth and daughters were born to them,
American Standard Version
And it came to pass, when men began to multiply on the face of the ground, and daughters were born unto them,
World English Bible Messianic
When men began to multiply on the surface of the ground, and daughters were born to them,
Geneva Bible (1599)
So when men began to be multiplied vpon the earth, and there were daughters borne vnto them,
Young's Literal Translation
And it cometh to pass that mankind have begun to multiply on the face of the ground, and daughters have been born to them,
Translation
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Summary

Genesis 6:1 serves as a critical narrative pivot, succinctly describing the rapid and widespread increase of the human population across the earth, specifically noting the birth of daughters. This seemingly natural demographic expansion, however, is presented not merely as a fulfillment of the creation mandate but as the ominous prelude to a period of profound moral corruption and divine grief, setting the stage for the cataclysmic judgment of the Great Flood and a significant turning point in God's interaction with humanity.

Context

Literary Context

This verse initiates a new and somber chapter in the Genesis narrative, shifting focus dramatically from the preceding genealogical record of Adam's descendants in Genesis 5. While Genesis 5 meticulously traces the lineage leading to Noah, highlighting longevity and the cycle of life and death, Genesis 6:1 abruptly introduces the escalating depravity of mankind. It functions as a crucial narrative hinge, immediately preceding the enigmatic account of the "sons of God" and "daughters of men" in Genesis 6:2, which directly precipitates the universal wickedness described in Genesis 6:5. Thus, Genesis 6:1 establishes the demographic conditions necessary for the widespread moral decay that necessitates divine intervention.

Historical & Cultural Context

In the ancient Near East, population growth was generally viewed as a blessing and a sign of divine favor, often linked to the fulfillment of creation mandates. The command to be fruitful and multiply was foundational. However, this verse, set against the backdrop of an increasingly populated world, hints at the dark side of unchecked human proliferation when moral and spiritual foundations erode. While specific cultural norms of the pre-Flood world are not explicitly detailed, the narrative implies a society that, despite its growth, had drifted far from the Creator's original design, leading to a pervasive corruption that would become the norm rather than the exception. The geographical setting is still the "face of the earth," indicating a widespread, global phenomenon rather than a localized event, emphasizing the universal scope of the impending judgment.

Key Themes

Genesis 6:1 contributes significantly to several overarching themes within the book of Genesis and the broader biblical narrative. It underscores the fulfillment and perversion of the creation mandate, where humanity successfully multiplies, yet this very success becomes the context for profound sin rather than righteous flourishing. It highlights the escalation of sin, demonstrating how human depravity, left unchecked, can rapidly spread and intensify within a growing population, leading to societal corruption on a global scale, as seen in Genesis 6:5-7. Furthermore, it serves as a prelude to divine judgment and redemption, setting the stage for one of the Bible's earliest and most dramatic acts of divine judgment—the Great Flood—which in turn foreshadows the need for ultimate redemption and a new beginning.

Exposition and Analysis

Key Word Analysis

men ʼâdâm' H120

Derived from a root meaning "ruddy," this term refers to humanity collectively, encompassing both male and female. Its use here underscores that the population increase was universal, involving the entire human race, not just a specific segment. This collective reference emphasizes the widespread nature of the subsequent moral decline.

began châlal' H2490

This primitive root primarily means "to bore" or "to open," and by implication, "to begin." However, it also carries the significant connotation of "to profane" or "to defile." While contextually it means "began," the secondary meaning subtly hints at the profaning or corrupting nature of humanity's new beginning or "opening wedge" into a period of widespread wickedness, setting a tone for the subsequent narrative.

multiply râbab' H7231

This root signifies increasing greatly, especially in number, to become many or manifold, even by the myriad. It emphasizes the rapid and extensive nature of human population growth. The use of this word confirms that God's initial command to be fruitful and multiply was indeed being fulfilled, but the context of the surrounding verses reveals the negative spiritual implications of this unchecked proliferation.

daughters bath' H1323

This word, meaning "daughter," is crucial for its specific narrative function. While general population growth is noted, the explicit mention of daughters being born directly anticipates and sets the stage for the events of Genesis 6:2, where the "sons of God" take wives from these "daughters of men," initiating the unique form of corruption that prompts divine judgment.

Verse Breakdown

"And it came to pass, when men began to multiply on the face of the earth,"

This opening clause marks a significant transition in the narrative, signaling a new phase in human history. The phrase "it came to pass" (וַיְהִי, vayhi) often introduces a pivotal event or a shift in the story's focus. Here, it highlights the successful fulfillment of God's command to humanity to be fruitful and multiply. The phrase "on the face of the earth" emphasizes the widespread and global nature of this population growth, indicating that humanity was spreading across the entire habitable world, setting the stage for a universal moral crisis.

"and daughters were born unto them,"

This seemingly simple statement provides a crucial detail that directly links to the subsequent verses. While the multiplication of "men" (humanity) generally implies the birth of both sons and daughters, the specific mention of "daughters" is not incidental. It serves as a direct narrative cue, preparing the reader for the unique and problematic interactions described in Genesis 6:2, where the "sons of God" are drawn to the "daughters of men." This specific demographic development acts as a catalyst for the escalating moral decay that leads to the Flood.

Literary Devices

Genesis 6:1 employs several literary devices to convey its profound significance. The most prominent is Foreshadowing, as the seemingly benign mention of population growth, particularly the birth of daughters, directly anticipates and sets the stage for the moral crisis detailed in the subsequent verses, especially Genesis 6:2. The phrase "And it came to pass" functions as a Transitional Marker, signaling a shift from the genealogical lists of Genesis 5 to a new, more dramatic phase of human history, characterized by escalating depravity. Furthermore, the verse utilizes Synecdoche by specifically mentioning "daughters" as a part representing the whole of the population growth, highlighting the particular aspect of this growth that will become central to the unfolding narrative of corruption. This concise verse, therefore, acts as a potent overture, pregnant with ominous implications for humanity's future.

Theological and Thematic Connections

Genesis 6:1, while brief, is theologically profound, illustrating how the very success of human proliferation, intended as a blessing, can become the backdrop for profound moral failure when divorced from divine guidance. It underscores the critical biblical theme that numerical growth or societal advancement does not inherently equate to spiritual flourishing. Instead, it highlights humanity's persistent tendency towards sin, demonstrating how a growing population, without a corresponding growth in righteousness, can rapidly descend into widespread corruption, necessitating divine intervention. This verse thus lays the groundwork for understanding the depth of human depravity that grieved God's heart and led to the drastic judgment of the Flood, simultaneously emphasizing God's unwavering attentiveness to the moral state of His creation.

Genesis 1:28This verse directly relates to the creation mandate given to humanity to "be fruitful and multiply," showing its fulfillment but also its perversion in the context of sin.
Genesis 6:5The population growth described in Genesis 6:1 provides the context for the widespread and pervasive wickedness detailed in this subsequent verse.
Romans 5:12This New Testament passage speaks to the universal spread of sin and death, providing a theological framework for understanding the escalating depravity seen in Genesis 6.

Reflection and Application

Genesis 6:1 offers a sobering reflection for contemporary society, reminding us that numerical growth—whether in population, technological advancement, or material prosperity—does not automatically signify moral or spiritual progress. This verse challenges us to critically examine the foundations upon which our own societies are built. Are our advancements accompanied by a deepening commitment to righteousness, justice, and compassion, or are they merely providing more opportunities for the proliferation of sin and self-interest? The narrative underscores God's meticulous observation of humanity's moral trajectory and the profound consequences that arise when a burgeoning population chooses to depart from His design. It calls us to consider the quality of our growth, urging us to cultivate spiritual maturity and ethical integrity within our communities, lest our own proliferation become a catalyst for greater depravity rather than a testament to God's glory.

Questions for Reflection

  1. How does the idea that population growth can lead to increased depravity challenge our modern assumptions about progress and development?
  2. In what ways might our own "multiplication" (e.g., in knowledge, technology, or wealth) inadvertently create conditions for moral decay if not guided by spiritual principles?
  3. What specific steps can individuals and communities take to ensure that growth is accompanied by spiritual and moral flourishing, rather than decline?

FAQ

Why does the verse specifically mention "daughters were born unto them"?

This detail is highly significant because it immediately precedes and sets up the narrative of Genesis 6:2, where the "sons of God" take wives from these "daughters of men." It highlights a specific demographic development that leads directly to the unique wickedness described in the following verses, not just general population growth. This particular mention serves as a crucial narrative cue, linking the population increase to the subsequent moral crisis.

Does "men" in this verse refer only to males, or to humanity in general?

The Hebrew word used, ha'adam (הָאָדָם), refers to humanity in general, encompassing both men and women. The verse describes the overall increase of the human population, emphasizing the widespread nature of this demographic shift across the earth.

Is population growth inherently negative according to this verse?

No, population growth itself is a fulfillment of God's original blessing and command to be fruitful and multiply. However, this verse highlights that numerical growth, when coupled with a lack of spiritual and moral grounding, can create conditions ripe for widespread corruption and sin, leading to negative consequences as seen in the subsequent narrative of the Flood.

What is the significance of the phrase "And it came to pass"?

This common biblical phrase (vayhi in Hebrew) often signals a transition or the beginning of a significant new event or phase in the narrative. Here, it marks the shift from the genealogies of Genesis 5 to the escalating moral crisis that precipitates the Great Flood, indicating a pivotal moment in God's dealings with humanity.

Christ-Centered Fulfillment

While Genesis 6:1 describes a period of increasing human population and impending judgment, it subtly points to humanity's desperate need for a new beginning and a radical divine intervention that ultimately finds its fulfillment in Christ. The widespread corruption that arose from this proliferation of mankind ultimately necessitated a divine cleansing, foreshadowing the ultimate spiritual cleansing and new creation offered through Jesus. Just as the "days of Noah" were characterized by humanity's preoccupation and unpreparedness for divine judgment (see Matthew 24:37-39), so too does the world often remain oblivious to its spiritual state. Noah and his family, preserved through the flood, represent a remnant saved by God's grace. In Christ, we find the true Ark of salvation, providing refuge from the judgment of sin. Through His atoning work, Jesus offers a new covenant and the promise of a new creation (compare 2 Corinthians 5:17), providing a righteous remnant for a spiritual new beginning, transcending the cycle of sin and judgment seen in Genesis.

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Public-domain commentary

Matthew Henry

From his Commentary on the Whole Bible. Henry comments on passages, not single verses — this entry covers Genesis 6:1–2.

1662–1714 · 2 verses
Passage under commentGenesis 6:1–2

For the glory of God's justice, and for warning to a wicked world, before the history of the ruin of the old world, we have a full account of its degeneracy, its apostasy from God and rebellion against him. The destroying of it was an act, not of an absolute sovereignty, but of necessary justice, for the maintaining of the honour of God's government. Now here we have an account of two things which occasioned the wickedness of the old world: - 1. The increase of mankind: Men began to multiply upon the face of the earth. This was the effect of the blessing (Gen 1:28), and yet man's corruption so abused and perverted this blessing that it was turned into a curse. Thus sin takes occasion by the mercies of God to be the more exceedingly sinful. Pro 29:16, When the wicked are multiplied, transgression increaseth. The more sinners the more sin; and the multitude of offenders emboldens men. Infectious diseases are most destructive in populous cities; and sin is a spreading leprosy. Thus in the New Testament church, when the number of the disciples was multiplied, there arose a murmuring (Act 6:1), and we read of a nation that was multiplied, not to the increase of their joy, Isa 9:3. Numerous families need to be well-governed, lest they become wicked families. 2. Mixed marriages (Gen 6:2): The sons of God (that is, the professors of religion, who were called by the name of the Lord, and called upon that name), married the daughters of men, that is, those that were profane, and strangers to God and godliness. The posterity of Seth did not keep by themselves, as they ought to have done, both for the preservation of their own purity and in detestation of the apostasy. They intermingled themselves with the excommunicated race of Cain: They took them wives of all that they chose. But what was amiss in these marriages? (1.) They chose only by the eye: They saw that they were fair, which was all they looked at. (2.) They followed the choice which their own corrupt affections made: they took all that they chose, without advice and consideration. But, (3.) That which proved of such bad consequence to them was that they married strange wives, were unequally yoked with unbelievers, Co2 6:14. This was forbidden to Israel, Deu 7:3, Deu 7:4. It was the unhappy occasion of Solomon's apostasy (Kg1 11:1-4), and was of bad consequence to the Jews after their return out of Babylon, Ezr 9:1, Ezr 9:2. Note, Professors of religion, in marrying both themselves and their children, should make conscience of keeping within the bounds of profession. The bad will sooner debauch the good than the good reform the bad. Those that profess themselves the children of God must not marry without his consent, which they have not if they join in affinity with his enemies.

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Historical interpretation

Seven Centuries of Reception

20 surviving comments on this verse. Each one is dated, so this reads as a timeline rather than a list.

20 quotes · AD 50–735
Ante-NicenePost-NiceneEarly Medieval
100200300400500600700

Select a marker to jump to its quote. Markers stagger vertically where authors wrote within a few decades of each other.

AD 50Philo of AlexandriaAnte-NiceneSourceON THE GIANTS
"And it came to pass when there began to be many men upon the earth, that daughters also were born to Them." [Genesis 6:1] I think it here worth while to raise the question why, after the birth of Noah and his sons, our race increased to a degree of great populousness. But, perhaps, it is not difficult to explain the cause of this; for it always happens if anything appears to be rare that its contrary is found exceedingly numerous. (2) Therefore, the good disposition of one displays the evil disposition of myriads, and the fact of those things which are done in accordance with art, and science, and virtue, and beauty, being few, shows how incalculable a number of things devoid of art, and of science, and of justice, and, in short, utterly worthless, lie concealed beneath. (3) Do you not see that in the universe, also, the sun, being one body, by his shining forth dissipates the thick and dense darkness which is shed over earth and sea? With great propriety, therefore, the generation of the just Noah and his sons is represented as bringing into existence a great number of unjust persons; for it is by the contrary that it is especially the nature of contraries to be known. (4) And no unjust man at any time implants a masculine generation in the soul, but such, being unmanly, and broken, and effeminate in their minds, do naturally become the parents of female children; having planted no tree of virtue, the fruit of which must of necessity have been beautiful and salutary, but only trees of wickedness and of the passions, the shoots of which are womanlike. (5) On account of which fact these men are said to have become the fathers of daughters, and that no one of them is said to have begotten a son; for since the just Noah had male children, as being a man who followed reason, perfect, and upright, and masculine, so by this very fact the injustice of the multitude is proved to be altogether the parent of female children. For it is impossible that the same things should be born of opposite parents; but they must necessarily have an opposite offspring.
For many angels of God accompanied with women, and begat sons that proved unjust, and despisers of all that was good, on account of the confidence they had in their own strength; for the tradition is, that these men did what resembled the acts of those whom the Grecians call giants. But Noah was very uneasy at what they did; and being displeased at their conduct, persuaded them to change their dispositions and their acts for the better: but seeing they did not yield to him, but were slaves to their wicked pleasures, he was afraid they would kill him, together with his wife and children, and those they had married; so he departed out of that land.
God, when He had made the whole world, and subjected things earthly to man, and arranged the heavenly elements for the increase of fruits and rotation of the seasons, and appointed this divine law-for these things also He evidently made for man-committed the care of men and of all things under heaven to angels whom He appointed over them. But the angels transgressed this appointment, and were captivated by love of women, and begat children who are those that are called demons; and besides, they afterwards subdued the human race to themselves, partly by magical writings, and partly by fears and the punishments they occasioned, and partly by teaching them to offer sacrifices, and incense, and libations, of which things they stood in need after they were enslaved by lustful passions; and among men they sowed murders, wars, adulteries, intemperate deeds, and all wickedness. Whence also the poets and mythologists, not knowing that it was the angels and those demons who had been begotten by them that did these things to men, and women, and cities, and nations, which they related, ascribed them to god himself, and to those who were accounted to be his very offspring, and to the offspring of those who were called his brother), Neptune and Pluto, and to the children again of these their offspring. For whatever name each of the angels had given to himself and his children, by that name they called them.
And for a very long while wickedness extended and spread, and reached and laid hold upon the whole race of mankind, until a very small seed of righteousness remained among them and illicit unions took place upon the earth, since angels were united with the daughters of the race of mankind; and they bore to them sons who for their exceeding greatness were called giants. And the angels brought as presents to their wives teachings of wickedness, in that they brought them the virtues of roots and herbs, dyeing in colors and cosmetics, the discovery of rare substances, love-potions, aversions, amours, concupiscence, constraints of love, spells of bewitchment, and all sorcery and idolatry hateful to God; by the entry of which things into the world evil extended and spread, while righteousness was diminished and enfeebled. Until judgment came upon the world from God by means of a flood, in the tenth generation from the first-formed (man); Noah alone being found righteous.
Since the Son of God is always one and the same, He gives to those who believe on Him a well of water [springing up] to eternal life, but He causes the unfruitful fig-tree immediately to dry up; and in the days of Noah He justly brought on the deluge for the purpose of extinguishing that most infamous race of men then existent, who could not bring forth fruit to God, since the angels that sinned had commingled with them, and [acted as He did] in order that He might put a check upon the sins of these men, but [that at the same time] He might preserve the archetype, the formation of Adam. And it was He who rained fire and brimstone from heaven, in the days of Lot, upon Sodom and Gomorrah, “an example of the righteous judgment of God,” that all may know, “that every tree that bringeth not forth good fruit shall be cut down, and cast into the fire.”
To which also we shall add, that the angels who had obtained the superior rank, having sunk into pleasures, told to the women the secrets which had come to their knowledge; while the rest of the angels concealed them, or rather, kept them against the coming of the Lord.
The mind is led astray by pleasure, and the virgin center of the mind, if not disciplined by the Word, degenerates into licentiousness and reaps disintegration as reward for its transgressions. An example of this for you is the angels who forsook the beauty of God for perishable beauty and fell as far as heaven is from the earth.
AD 220TertullianAnte-NiceneSourceOn Prayer
What is "every woman, but woman of every age, of every rank, of every condition? By saying" every" he excepts nought of womanhood, just as he excepts nought of manhood either from not being covered; for just so he says, "Every man." As, then, in the masculine sex, under the name of" man" even the" youth" is forbidden to be veiled; so, too, in the feminine, under the name of "woman," even the "virgin" is bidden to be veiled. Equally in each sex let the younger age follow the discipline of the elder; or else let the male "virgins," too, be veiled, if the female virgins withal are not veiled, because they are not mentioned by name. Let "man" and "youth" be different, if "woman" and "virgin" are different. For indeed it is "on account of the angels" that he saith women must be veiled, because on account of "the daughters of men" angels revolted from God.
For they, withal, who instituted them are assigned, under condemnation, to the penalty of death — those angels, to wit, who rushed from heaven on the daughters of men; so that this ignominy also attaches to woman. For when to an age much more ignorant (than ours) they had disclosed certain well-concealed material substances, and several not well-revealed scientific arts — if it is true that they had laid bare the operations of metallurgy, and had divulged the natural properties of herbs, and had promulgated the powers of enchantments, and had traced out every curious art, even to the interpretation of the stars — they conferred properly and as it were peculiarly upon women that instrumental mean of womanly ostentation, the radiances of jewels wherewith necklaces are variegated, and the circlets of gold wherewith the arms are compressed, and the medicaments of orchil with which wools are colored, and that black powder itself wherewith the eyelids and eyelashes are made prominent. What is the quality of these things may be declared meantime, even at this point, from the quality and condition of their teachers: in that sinners could never have either shown or supplied anything conducive to integrity, unlawful lovers anything conducive to chastity, renegade spirits anything conducive to the fear of God. If (these things) are to be called teachings, ill masters must of necessity have taught ill; if as wages of lust, there is nothing base of which the wages are honourable. But why was it of so much importance to show these things as well as to confer them? Was it that women, without material causes of splendour, and without ingenious contrivances of grace, could not please men, who, while still unadorned, and uncouth and — so to say — crude and rude, had moved (the mind of) angels? Or was it that the lovers would appear sordid and — through gratuitous use — contumelious, if they had conferred no (compensating) gift on the women who had been enticed into connubial connection with them? But these questions admit of no calculation. Women who possessed angels (as husbands) could desire nothing more; they had, forsooth, made a grand match! Assuredly they who, of course, did sometimes think whence they had fallen, and, after the heated impulses of their lusts, looked up toward heaven, thus requited that very excellence of women, natural beauty, as (having proved) a cause of evil, in order that their good fortune might profit them nothing; but that, being turned from simplicity and sincerity, they, together with (the angels) themselves, might become offensive to God. Sure they were that all ostentation, and ambition, and love of pleasing by carnal means, was displeasing to God. And these are the angels whom we are destined to judge: these are the angels whom in baptism we renounce: these, of course, are the reasons why they have deserved to be judged by man. What business, then, have their things with their judges? What commerce have they who are to condemn with them who are to be condemned? The same, I take it, as Christ has with Belial. With what consistency do we mount that (future) judgment-seat to pronounce sentence against those whose gifts we (now) seek after? For you too, (women as you are,) have the self-same angelic nature promised as your reward, the self-same sex as men: the self-same advancement to the dignity of judging, does (the Lord) promise you. Unless, then, we begin even here to pre-judge, by pre-condemning their things, which we are hereafter to condemn in themselves, they will rather judge and condemn us.
AD 240Julius Africanusas quoted by George Syncellus, AD 810Ante-NiceneSourceFragment 2
When men multiplied on the earth, the angels of heaven came together with the daughters of men. In some copies I found "the sons of God." What is meant by the Spirit, in my opinion, is that the descendants of Seth are called the sons of God on account of the righteous men and patriarchs who have sprung from him, even down to the Saviour Himself; but that the descendants of Cain are named the seed of men, as having nothing divine in them, on account of the wickedness of their race and the inequality of their nature, being a mixed people, and having stirred the indignation of God. But if it is thought that these refer to angels, we must take them to be those who deal with magic and jugglery, who taught the women the motions of the stars and the knowledge of things celestial, by whose power they conceived the giants as their children, by whom wickedness came to its height on the earth, until God decreed that the whole race of the living should perish in their impiety by the deluge.
But when they did nothing of this kind, but tried to make supplication to the evil daemons by a foul and licentious life and unseemly words, and by feeding on raw flesh, and rending victims asunder, and by human sacrifices, how was it even possible that doing such deeds, and pursuing practices pleasing to the wicked, they should be received as friends by the Supreme God, or by the divine Powers subject to Him, or by any good beings at all?

But in fact it is manifest to all that he who practises the things that are dear to the wicked can never be a friend of the good. So then it was not to gods, nor yet to good daemons, but only to the wicked, that those of whom I have spoken paid worship.

And this argument is still further confirmed by Plutarch, in the passage where he says that the mythical narratives told as concerning gods are certain tales about daemons, and the deeds of Giants and Titans celebrated in song among the Greeks are also stories about daemons, intended to suggest a new phase of thought.

Of this kind then perhaps were the statements in the Sacred Scripture concerning the giants before the flood, and those concerning their progenitors, of whom it is said, 'And when the angels of God saw the daughters of men that they were fair, they took unto them wives of all that they chose,' and of these were born 'the giants the men of renown which were of old.'

For one might say that these daemons are those giants, and that their spirits have been deified by the subsequent generations of men, and that their battles, and their quarrels among themselves, and their wars are the subjects of these legends that are told as of gods.
Again after these a third appeared: Noah who has received testimony as 'a righteous man in his generation.' And the following will be proofs of his righteousness. A great foulness and darkness of indescribable wickedness had overtaken the whole human race, and the giants talked of by every mouth were carrying on with ungodly and impious efforts their wars with God which are still so celebrated: and already the fathers of this their brood, whether they had sprung from some condition mightier than man's nature, or in whatever way endowed, are said to have begun the teaching of curious arts among men, and to have introduced devices of witchcraft and other mischievous sorcery into their life, so that the whole human race had fallen under one sentence of judgement with God.
AD 373Ephrem the SyrianPost-NiceneSourceCOMMENTARY ON GENESIS 6.3.1
[Moses] called the sons of Seth “sons of God,” those who, like the sons of Seth, had been called “the righteous people of God.” The beautiful daughters of men whom they saw were the daughters of Cain who adorned themselves and became a snare to eyes of the sons of Seth. Then Moses said “they took to wife such of them as they chose,” because when “they took” them, they acted very haughtily over those whom they chose. A poor one would exalt himself over the wife of a rich man, and an old man would sin with one who was young. The ugliest of all would act arrogantly over the most beautiful.
He called the sons of Seth sons of God, those who, like the sons of Seth, had been called "the righteous people of God." The beautiful daughters of men whom they saw were the daughters of Cain who adorned themselves and became a snare to the eyes of the sons of Seth. Then Moses said, they took them wives of all which they chose.
AD 390Nemesius of EmesaPost-NiceneSourceON THE NATURE OF MAN 58
Of the incorporeal beings, only angels fell away, and not all of them, but some only, that inclined to things below and set their desire on things of earth, withdrawing themselves from their relations with things above, even from God.
"Now, when the sons of God saw that the daughters of men were beautiful, they took wives for themselves from them all just as they were inclined." Let us study each expression of this statement closely so that nothing of what is hidden below the surface may pass us by. You see, there is need to make a careful study of this passage and confute the fanciful interpretations of those people whose every remark is made rashly - firstly, to repeat what they presume to say, and by demonstrating the absurdity of what is said by them to teach your good selves the true sense of Scripture so that you will not lend your ears idly to people uttering those blasphemies and presuming to speak in a way that brings their own persons into jeopardy. I mean, they claim that this remark is made not about human being but about angels; these (they say) he called sons of God. Let them demonstrate firstly where angels are called sons of God; they would not, however, be able to show this anywhere. While human beings are called sons of God, angels are nowhere so called. On the contrary, it speaks about angels in these terms: "He makes the winds his angels, fire and flame his ministers," whereas about human beings, "I said, You are gods," and again, "Sons have I begotten and raised," and again, "Israel my firstborn son" - but an angel is nowhere called son, or son of God. What in fact do they claim? To be sure, they really were angels, but because they fell into this lawless way, they lost their status...

Is it not a particular hallmark of folly to claim that angels descended to have intercourse with women, and that incorporeal nature of theirs was reduced to association with corporeal creatures? Or do you not hear the words of Christ about the being of angels, "At the resurrection they neither marry nor are given in marriage, but are like angels of God"? After all, it is not for that kind of incorporeal creature to ever feel the onset of desire. In response to these people we have to reach the same conclusion, that to admit this notion into one's mind is the height of absurdity.

We made the point before in teaching you that it is customary with Scripture to call human beings sons of God. So since these people took their origin from Seth and from his son named Enosh (the text, remember, saying, "He it was who hoped to invoke the name of the Lord God"), those descended from him in the future were called sons of God by Sacred Scripture for the reason of their imitation of the virtue of their ancestors up to his time. On the other hand, he gave the name sons of men to those born after Seth, the descendants of Cain and those taking their descent from him.
As long then as there continued that separation of the lines between them, the seed of Seth, as it sprang from an excellent root, was by reason of its sanctity termed "angels of God," or as some copies have it "sons of God;" and on the contrary the others by reason of their own and their fathers' wickedness and their earthly deeds were termed "children of men." Though then there was up to this time that holy and salutary separation between them, yet after this the sons of Seth who were the sons of God saw the daughters of those who were born of the line of Cain, and inflamed with the desire for their beauty took to themselves from them wives who taught their husbands the wickedness of their fathers, and at once led them astray from their innate holiness and the single-mindedness of their forefathers...From these sons of Seth then and daughters of Cain, as we have said, there were I born still worse children who became mighty hunters, violent and most fierce men who were termed giants by reason of the size of their bodies and their cruelty and wickedness. For these first began to harass their neighbours and to practise pillaging among men, getting their living rather by rapine than by being contented with the sweat and labour of toil, and their wickedness increased to such a pitch that the world could only be purified by the flood and deluge.
That we rightly understand this passage is also very much confirmed by the interpretation of the other translators. Aquila says: 'When the sons of the gods saw the daughters of men'. On the other hand, instead of 'sons of the gods', Symmachus rendered the expression as 'sons of the rulers'. They called the descendants of Seth and of Enosh sons of the gods, or better, sons of the rulers, because of the piety and godliness which was in them, and because they could defeat all adversaries: while God, I suppose, in all likelihood came to their aid, and made known all around this pious and holy generation, which was not mixed with that other one, that is to say, with the descendants from Cain and, what is more, from Lamech.
AD 735BedeEarly MedievalSourceCommentary on Genesis (Hexaemeron)
And when men began to multiply on the earth and had daughters, the sons of God saw the daughters of men that they were fair; and they took wives for themselves of all whom they chose. "Men" means the offspring of Cain, who, turned away from the view of divine will, subjected their mind solely to human affairs: "sons of God", however, refers to those who were born from the lineage of Seth, who, following the example of their father's devotion, preserved with an inviolate mind the service they owed to God. By this distinction, the Lord in the Gospel also separated His disciples from the rest, saying, "Whom do men say that the Son of Man is?" (Matthew 16:13). And having received their answer, He said, "But who do you say that I am?" evidently wanting them to be understood as superior to men and to be counted among those of whom He Himself said: "I have said, You are gods; and all of you are children of the Most High" (Psalm 82:6). Some manuscripts have "angels of God" instead of "sons of God," which is obviously taken in the same sense. For the angels of God are rightly called righteous men, who according to the measure of their capacity strive to live an angelic life on earth: to such the Apostle says, "But you are not in the flesh, but in the Spirit" (Romans 8:9). And again: "For our conversation is in heaven" (Philippians 3:20). Therefore, it seems that the generation of the lineage of Seth, as long as it was not mingled with the offspring of Cain, preserved the norm of its chastity untainted; but after it fell into concupiscence and joined the cursed offspring of wicked women, it also began to share in the curse with the corrupted decency of its sober mind. Hence, in the law it is diligently and carefully commanded to the sons of Israel, not to intermarry with foreigners, because, it says, “his daughter will seduce your son to follow their gods” (Deuteronomy 7:4).
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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