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Translation
King James Version
Professing themselves to be wise, they became fools,
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KJV (with Strong's)
Professing themselves G5335 to be G1511 wise G4680, they became fools G3471,
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Complete Jewish Bible
Claiming to be wise, they have become fools!
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Berean Standard Bible
Although they claimed to be wise, they became fools,
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American Standard Version
Professing themselves to be wise, they became fools,
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World English Bible Messianic
Professing themselves to be wise, they became fools,
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Geneva Bible (1599)
When they professed themselues to be wise, they became fooles.
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Young's Literal Translation
professing to be wise, they were made fools,
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Study This Verse

SUMMARY

Romans 1:22 powerfully encapsulates the tragic irony of humanity's rebellion against God: those who, in their intellectual pride, claimed to possess ultimate wisdom and understanding apart from divine revelation, ultimately descended into profound spiritual and moral foolishness. This verse serves as a critical point in Paul's argument for universal human sinfulness, demonstrating that the rejection of God's clear self-disclosure leads not to enlightenment but to a perversion of truth and a darkened mind.

CONTEXT

  • Literary Context: Romans 1:22 is embedded within Paul's comprehensive indictment of human sinfulness, which begins in Romans 1:18 and extends through Romans 3:20. The preceding verse, Romans 1:21, establishes the foundational issue: "Although they knew God, they did not glorify him as God or give thanks to him, but their thinking became futile and their foolish hearts were darkened." Verse 22 then elaborates on the consequence of this intellectual and spiritual decline, specifically targeting the self-deception of those who believe they are wise without God. This leads directly into the description of humanity's descent into idolatry (Romans 1:23) and subsequent moral depravity (Romans 1:24-32), illustrating the progressive nature of God's judgment as He gives humanity over to its own chosen path.

  • Historical & Cultural Context: Paul's letter to the Romans was written to a diverse church in the heart of the Roman Empire, a society that prided itself on its philosophical traditions, legal systems, and intellectual achievements. Greek philosophy, with its emphasis on human reason and logic, heavily influenced the intellectual climate. In this context, claiming "wisdom" was a significant assertion of intellectual and moral superiority, often independent of, or even in opposition to, traditional religious beliefs. Paul's critique in Romans 1 directly challenges the prevailing Greco-Roman worldview that elevated human reason and self-sufficiency, asserting that true wisdom originates from God alone. The cultural backdrop of widespread idolatry and moral decadence, even among those considered "wise" by worldly standards, provides a stark illustration of the "foolishness" Paul describes.

  • Key Themes: This verse contributes significantly to several major themes in Romans and the broader biblical narrative. It underscores the theme of Human Pride and Rebellion, highlighting how humanity's attempt to achieve wisdom apart from God is an act of self-exaltation that inevitably leads to spiritual downfall. It also develops the theme of Divine Judgment, showing that God's wrath is not arbitrary but a righteous response to humanity's suppression of truth and rejection of His self-revelation. The verse starkly contrasts True Wisdom vs. Worldly Wisdom, echoing the Old Testament's emphasis that "The fear of the Lord is the beginning of wisdom" (Proverbs 9:10). Paul will further elaborate on this contrast in 1 Corinthians, where he explains that "the foolishness of God is wiser than human wisdom" (1 Corinthians 1:25). Ultimately, Romans 1:22 sets the stage for the necessity of God's righteousness revealed through faith in Christ, as human wisdom proves utterly incapable of saving humanity from its self-inflicted foolishness.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • Professing (Greek, pháskō', G5335): From the root meaning "to assert" or "to say," this word implies a deliberate, often self-congratulatory, declaration. It's not merely thinking something but actively claiming it publicly, suggesting a pretense or a false front of intellectual superiority. This "professing" signifies an active, conscious assertion of their own wisdom.
  • Wise (Greek, sophós', G4680): This term refers to general wisdom, encompassing intellectual insight, practical skill, and moral discernment. In the context of Romans 1, it points to human reason, philosophy, and self-derived knowledge, often contrasted with divine revelation. It describes those who consider themselves intellectually enlightened and morally astute by their own standards.
  • Fools (Greek, mōraínō', G3471): Derived from mōrós (from which we get "moron"), this verb means "to become insipid," "to make foolish," or "to act as a simpleton." It is in the aorist passive tense, indicating a definite, completed action that happened to them. It denotes an active process of degradation, where their supposed wisdom leads to a state of utter spiritual and intellectual bankruptcy in God's eyes. It's not merely a lack of wisdom but a perversion of it, resulting in a state of being rendered foolish.

Verse Breakdown

  • "Professing themselves to be wise": This opening clause highlights humanity's self-assessment and declaration of intellectual prowess. It describes those who, relying on their own reasoning and philosophical systems, claim to possess ultimate truth and understanding apart from divine revelation. This is an act of human pride, asserting self-sufficiency in knowledge and often dismissing the need for God. This "professing" is not just internal thought but an outward declaration, perhaps through philosophical systems, moral codes, or scientific endeavors that exclude the Creator.
  • "they became fools": This contrasting clause reveals the divine verdict on such human pretension. The verb "became" (aorist passive of mōraínō) indicates a definite, completed action, a consequence of their professing. Their self-proclaimed wisdom led not to enlightenment but to a profound spiritual and intellectual degradation, rendering them utterly foolish in God's sight. This is the tragic irony: their pursuit of wisdom outside God resulted in the very opposite of what they sought. This foolishness manifests in their inability to discern spiritual truth and their propensity for idolatry and immorality, as described in the subsequent verses.

Literary Devices

Romans 1:22 is a masterclass in rhetorical force, primarily employing Irony and Antithesis. The central Irony lies in the stark contrast between humanity's self-perception and God's reality: those who boast of their wisdom are precisely those who have become foolish. This dramatic reversal underscores the futility and self-deception inherent in rejecting divine truth. Furthermore, the verse employs Antithesis, directly juxtaposing "wise" and "fools" to highlight the profound spiritual chasm between human arrogance and divine judgment. This sharp contrast emphasizes the catastrophic spiritual fall that results from suppressing the truth about God, demonstrating that what humanity considers the pinnacle of intellect, God declares as utter spiritual bankruptcy. The passive voice of "became fools" (Greek: emōranthēsan) subtly implies that this state is not merely self-inflicted but also a consequence of God "giving them over" (as seen in Romans 1:24, 26, 28) to the natural consequences of their choices.

THEOLOGICAL AND THEMATIC CONNECTIONS

This verse profoundly articulates a core biblical truth: true wisdom is not found in human intellect or philosophical systems divorced from God, but in acknowledging and submitting to Him as the Creator and Lord. The human tendency to elevate self-reasoning above divine revelation leads inevitably to spiritual darkness and moral decay. This is a recurring theme throughout Scripture, where the "wise" of the world are often depicted as foolish in God's eyes, and what seems foolish to the world is God's profound wisdom. The rejection of God's clear self-disclosure, as described in the preceding verses, culminates in a darkened understanding, rendering humanity incapable of discerning ultimate truth or living righteously.

REFLECTION AND APPLICATION

Romans 1:22 serves as a timeless and sobering warning against intellectual arrogance and the dangers of relying solely on human reason. In a world that often exalts scientific discovery, philosophical thought, and personal autonomy as the ultimate sources of truth, this verse reminds us that genuine wisdom begins with a humble acknowledgment of God as our Creator and Sustainer. When we exclude God from our pursuit of knowledge, we risk becoming spiritually blind, making choices that, while seemingly rational by worldly standards, are fundamentally foolish in their ultimate consequences. This challenges us to critically evaluate the sources of our understanding and to prioritize God's revealed truth above all human ideologies. It calls us to cultivate a posture of humility, recognizing that true enlightenment comes not from within ourselves, but from the divine wisdom found in God's Word and His Son, Jesus Christ.

Questions for Reflection

  • In what areas of my life might I be "professing myself to be wise" while neglecting God's perspective?
  • How does the world's definition of "wisdom" differ from God's definition, and how might this influence my thinking?
  • What practical steps can I take to cultivate a greater reliance on God's wisdom rather than my own understanding?

FAQ

What does it mean that "they became fools" in this context?

Answer: In Romans 1:22, "they became fools" means that humanity, by rejecting God despite knowing Him, actively degraded their own understanding and spiritual discernment. It's not merely a lack of knowledge, but a perversion of it. The Greek word mōraínō implies a state of being rendered insipid or foolish, suggesting that their supposed wisdom led them to a condition of spiritual and intellectual bankruptcy in God's eyes. This foolishness is evidenced by their descent into idolatry and immoral practices, as described in the subsequent verses of Romans 1. Their rejection of divine truth resulted in a darkened mind, incapable of perceiving spiritual reality.

CHRIST-CENTERED FULFILLMENT

Romans 1:22, by exposing the futility of human wisdom apart from God, powerfully sets the stage for the necessity of Christ. Humanity's self-proclaimed wisdom led to foolishness, demonstrating its utter inability to save itself or even truly know God. This profound spiritual bankruptcy highlights the desperate need for a divine intervention, which is precisely what God provides in Jesus Christ. The "foolishness" of the cross, as Paul later explains in 1 Corinthians 1, is God's ultimate wisdom, confounding the wise of this world. While humanity sought wisdom in its own reason, God revealed His true wisdom and power in Christ crucified, who became for us "wisdom from God—that is, our righteousness, holiness and redemption" (1 Corinthians 1:30). Thus, the very foolishness condemned in Romans 1:22 underscores the glorious truth that salvation and true wisdom are found not in human striving, but in the humble acceptance of God's "foolish" plan of redemption through His Son, Jesus, the Lamb of God who takes away the sin of the world.

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Commentary on Romans 1 verses 19–32

I. II. Main points1. 2. Sub-points(1.) (2.) Details[1.] [2.] Fine details

In this last part of the chapter the apostle applies what he had said particularly to the Gentile world, in which we may observe,

I. The means and helps they had to come to the knowledge of God. Though they had not such a knowledge of his law as Jacob and Israel had (Psa 147:20), yet among them he left not himself without witness (Act 14:17): For that which may be known, etc., Rom 1:19, Rom 1:20. Observe,

1.What discoveries they had: That which may be known of God is manifest, en autois - among them; that is, there were some even among them that had the knowledge of God, were convinced of the existence of one supreme Numen. The philosophy of Pythagoras, Plato, and the Stoics, discovered a great deal of the knowledge of God, as appears by abundance of testimonies. That which may be known, which implies that there is a great deal which may not be known. The being of God may be apprehended, but cannot be comprehended. We cannot by searching find him out, Job 11:7-9. Finite understandings cannot perfectly know an infinite being; but, blessed be God, there is that which may be known, enough to lead us to our chief end, the glorifying and enjoying of him; and these things revealed belong to us and to our children, while secret things are not to be pried into, Deu 29:29.

2.Whence they had these discoveries: God hath shown it to them. Those common natural notions which they had of God were imprinted upon their hearts by the God of nature himself, who is the Father of lights. This sense of a Deity, and a regard to that Deity, are so connate with the human nature that some think we are to distinguish men from brutes by these rather than by reason.

3.By what way and means these discoveries and notices which they had were confirmed and improved, namely, by the work of creation (Rom 1:20); For the invisible things of God, etc.

(1.)Observe what they knew: The invisible things of him, even his eternal power and Godhead. Though God be not the object of sense, yet he hath discovered and made known himself by those things that are sensible. The power and Godhead of God are invisible things, and yet are clearly seen in their products. He works in secret (Job 23:8, Job 23:9; Psa 139:15; Ecc 11:5), but manifests what he has wrought, and therein makes known his power and Godhead, and others of his attributes which natural light apprehends in the idea of a God. They could not come by natural light to the knowledge of the three persons in the Godhead (though some fancy they have found footsteps of this in Plato's writings), but they did come to the knowledge of the Godhead, at least so much knowledge as was sufficient to have kept them from idolatry. This was that truth which they held in unrighteousness.

(2.)How they knew it: By the things that are made, which could not make themselves, nor fall into such an exact order and harmony by any casual hits; and therefore must have been produced by some first cause or intelligent agent, which first cause could be no other than an eternal powerful God. See Psa 19:1; Isa 40:26; Act 17:24. The workman is known by his work. The variety, multitude, order, beauty, harmony, different nature, and excellent contrivance, of the things that are made, the direction of them to certain ends, and the concurrence of all the parts to the good and beauty of the whole, do abundantly prove a Creator and his eternal power and Godhead. Thus did the light shine in the darkness. And this from the creation of the world. Understand it either, [1.] As the topic from which the knowledge of them is drawn. To evince this truth, we have recourse to the great work of creation. And some think this ktisis kosmou, this creature of the world (as it may be read), is to be understood of man, the ktisis kat' exochēn - the most remarkable creature of the lower world, called ktisis, Mar 16:15. The frame and structure of human bodies, and especially the most excellent powers, faculties, and capacities of human souls, do abundantly prove that there is a Creator, and that he is God. Or, [2.] As the date of the discovery. It as old as the creation of the world. In this sense apo ktiseōs is most frequently used in scripture. These notices concerning God are not any modern discoveries, hit upon of late, but ancient truths, which were from the beginning. The way of the acknowledgement of God is a good old way; it was from the beginning. Truth got the start of error.

II. Their gross idolatry, notwithstanding these discoveries that God made to them of himself; described here, Rom 1:21-23, Rom 1:25. We shall the less wonder at the inefficacy of these natural discoveries to prevent the idolatry of the Gentiles if we remember how prone even the Jews, who had scripture light to guide them, were to idolatry; so miserably are the degenerate sons of men plunged in the mire of sense. Observe,

1.The inward cause of their idolatry, Rom 1:21, Rom 1:22. They are therefore without excuse, in that they did know God, and from what they knew might easily infer that it was their duty to worship him, and him only. Though some have greater light and means of knowledge than others, yet all have enough to leave them inexcusable. But the mischief of it was that, (1.) They glorified him not as God. Their affections towards him, and their awe and adoration of him, did not keep pace with their knowledge. To glorify him as God is to glorify him only; for there can be but one infinite: but they did not so glorify him, for they set up a multitude of other deities. To glorify him as God is to worship him with spiritual worship; but they made images of him. Not to glorify God as God is in effect not to glorify him at all; to respect him as a creature is not to glorify him, but to dishonour him. (2.) Neither were they thankful; not thankful for the favours in general they received from God (insensibleness of God's mercies is at the bottom of our sinful departures from him); not thankful in particular for the discoveries God was pleased to make of himself to them. Those that do not improve the means of knowledge and grace are justly reckoned unthankful for them. (3.) But they became vain in their imaginations, en tois dialogismois - in their reasonings, in their practical inferences. They had a great deal of knowledge of general truths (Rom 1:19), but no prudence to apply them to particular cases. Or, in their notions of God, and the creation of the world, and the origination of mankind, and the chief good; in these things, when they quitted the plain truth, they soon disputed themselves into a thousand vain and foolish fancies. The several opinions and hypotheses of the various sects of philosophers concerning these things were so many vain imaginations. When truth is forsaken, errors multiply in infinitum - infinitely. (4.) And their foolish heart was darkened. The foolishness and practical wickedness of the heart cloud and darken the intellectual powers and faculties. Nothing tends more to the blinding and perverting of the understanding than the corruption and depravedness of the will and affections. (5.) Professing themselves to be wise, they became fools, Rom 1:22. This looks black upon the philosophers, the pretenders to wisdom and professors of it. Those that had the most luxuriant fancy, in framing to themselves the idea of a God, fell into the most gross and absurd conceits: and it was the just punishment of their pride and self-conceitedness. It has been observed that the most refined nations, that made the greatest show of wisdom, were the arrantest fools in religion. The barbarians adored the sun and moon, which of all others was the most specious idolatry; while the learned Egyptians worshipped an ox and an onion. The Grecians, who excelled them in wisdom, adored diseases and human passions. The Romans, the wisest of all, worshipped the furies. And at this day the poor Americans worship the thunder; while the ingenious Chinese adore the devil. Thus the world by wisdom knew not God, Co1 1:21. As a profession of wisdom is an aggravation of folly, so a proud conceit of wisdom is the cause of a great deal of folly. Hence we read of few philosophers who were converted to Christianity; and Paul's preaching was no where so laughed at and ridiculed as among the learned Athenians, Act 17:18-32. Phaskontes einai - conceiting themselves to be wise. The plain truth of the being of God would not content them; they thought themselves above that, and so fell into the greatest errors.

2.The outward acts of their idolatry, Rom 1:23-25. (1.) Making images of God (Rom 1:23), by which, as much as in them lay, they changed the glory of the incorruptible God. Compare Psa 106:20; Jer 2:11. They ascribed a deity to the most contemptible creatures, and by them represented God. It was the greatest honour God did to man that he made man in the image of God; but it is the greatest dishonour man has done to God that he has made God in the image of man. This was what God so strictly warned the Jews against, Deu 4:15, etc. This the apostle shows the folly of in his sermon at Athens, Act 17:29. See Isa 40:18, etc.; Isa 44:10, etc. This is called (Rom 1:25) changing the truth of God into a lie. As it did dishonour his glory, so it did misrepresent his being. Idols are called lies, for they belie God, as if he had a body, whereas he is a Spirit, Jer 23:14; Hos 7:1. Teachers of lies, Hab 2:18. (2.) Giving divine honour to the creature: Worshipped and served the creature, para ton ktisanta - besides the Creator. They did own a supreme Numen in their profession, but they did in effect disown him by the worship they paid to the creature; for God will be all or none. Or, above the Creator, paying more devout respect to their inferior deities, stars, heroes, demons, thinking the supreme God inaccessible, or above their worship. The sin itself was their worshipping the creature at all; but this is mentioned as an aggravation of the sin, that they worshipped the creature more than the Creator. This was the general wickedness of the Gentile world, and became twisted in with their laws and government; in compliance with which even the wise men among them, who knew and owned a supreme God and were convinced of the nonsense and absurdity of their polytheism and idolatry, yet did as the rest of their neighbours did. Seneca, in his book De Superstitione, as it is quoted by Aug. de Civit. Dei, lib. 6, cap. 10 (for the book itself is lost), after he had largely shown the great folly and impiety of the vulgar religion, in divers instances of it, yet concludes, Quae omnia sapiens servabit tanquam legibus jussa, non tanquam diis grata - All which a wise man will observe as established by law, not imagining them grateful to the gods. And afterwards, Omnem istam ignobilem deorum turbam, quam longo aevo longa superstitio congessit, sic adorabimus, ut meminerimus cultum ejus magis ad morem quam ad rem pertinere - All this ignoble rout of gods, which ancient superstition has amassed together by long prescription, we will so adore as to remember that the worship of them is rather a compliance with custom than material in itself. Upon which Augustine observes, Colebat quod reprehendebat, agebat quod arguebat, quod culpabat adorabat - He worshipped that which he censured, he did that which he had proved wrong, and he adored what he found fault with. I mention this thus largely because methinks it doth fully explain that of the apostle here (Rom 1:18): Who hold the truth in unrighteousness. It is observable that upon the mention of the dishonour done to God by the idolatry of the Gentiles the apostle, in the midst of his discourse, expresses himself in an awful adoration of God: Who is blessed for ever. Amen. When we see or hear of any contempt cast upon God or his name, we should thence take occasion to think and speak highly and honourably of him. In this, as in other things, the worse others are, the better we should be. Blessed for ever, notwithstanding these dishonours done to his name: though there are those that do not glorify him, yet he is glorified, and will be glorified to eternity.

III. The judgments of God upon them for this idolatry; not many temporal judgments (the idolatrous nations were the conquering ruling nations of the world), but spiritual judgments, giving them up to the most brutish and unnatural lusts. Paredōken autous - He gave them up; it is thrice repeated here, Rom 1:24, Rom 1:26, Rom 1:28. Spiritual judgments are of all judgments the sorest, and to be most dreaded. Observe,

1.By whom they were given up. God gave them up, in a way of righteous judgment, as the just punishment of their idolatry - taking off the bridle of restraining grace - leaving them to themselves - letting them alone; for his grace is his own, he is debtor to no man, he may give or withhold his grace at pleasure. Whether this giving up be a positive act of God or only privative we leave to the schools to dispute: but this we are sure of that it is no new thing for God to give men up to their own hearts' lusts, to send them strong delusions, to let Satan loose upon them, nay, to lay stumbling-blocks before them. And yet God is not the author of sin, but herein infinitely just and holy; for, though the greatest wickedness follow upon this giving up, the fault of that is to be laid upon the sinner's wicked heart. If the patient be obstinate, and will not submit to the methods prescribed, but wilfully takes and does that which is prejudicial to him, the physician is not to be blamed if he give him up as in a desperate condition; and all the fatal symptoms that follow are not to be imputed to the physician, but to the disease itself and to the folly and wilfulness of the patient.

2.To what they were given up.

(1.)To uncleanness and vile affections, Rom 1:24, Rom 1:26, Rom 1:27. Those that would not entertain the more pure and refined notices of natural light, which tend to preserve the honour of God, justly forfeited those more gross and palpable sentiments which preserve the honour of human nature. Man being in honour, and refusing to understand the God that made him, thus becomes worse than the beasts that perish, Psa 49:20. Thus one, by the divine permission, becomes the punishment of another; but it is (as it said here) through the lusts of their own hearts - there all the fault is to be laid. Those who dishonoured God were given up to dishonour themselves. A man cannot be delivered up to a greater slavery than to be given up to his own lusts. Such are given over, like the Egyptians (Isa 19:4), into the hand of a cruel lord. The particular instances of their uncleanness and vile affections are their unnatural lusts, for which many of the heathen, even of those among them who passed for wise men, as Solon and Zeno, were infamous, against the plainest and most obvious dictates of natural light. The crying iniquity of Sodom and Gomorrah, for which God rained hell from heaven upon them, became not only commonly practised, but avowed, in the pagan nations. Perhaps the apostle especially refers to the abominations that were committed in the worship of their idol-gods, in which the worst of uncleannesses were prescribed for the honour of their gods; dunghill service for dunghill gods: the unclean spirits delight in such ministrations. In the church of Rome, where the pagan idolatries are revived, images worshipped, and saints only substituted in the room of demons, we hear of these same abominations going barefaced, licensed by the pope (Fox's Acts and Monuments, vol. 1, p. 808), and not only commonly perpetrated, but justified and pleaded for by some of their cardinals: the same spiritual plagues for the same spiritual wickednesses. See what wickedness there is in the nature of man. How abominable and filthy is man! Lord, what is man? says David; what a vile creature is he when left to himself! How much are we beholden to the restraining grace of God for the preserving any thing of the honour and decency of the human nature! For, were it not for this, man, who was made but little lower than the angels, would make himself a great deal lower than the devils. This is said to be that recompence of their error which was meet. The Judge of all the earth does right, and observes a meetness between the sin and the punishment of it.

(2.)To a reprobate mind in these abominations, Rom 1:28.

[1.]They did not like to retain God in their knowledge. The blindness of their understandings was caused by the wilful aversion of their wills and affections. They did not retain God in their knowledge, because they did not like it. They would neither know nor do any thing but just what pleased themselves. It is just the temper of carnal hearts; the pleasing of themselves is their highest end. There are many that have God in their knowledge, they cannot help it, the light shines so fully in their faces; but they do not retain him there. They say to the Almighty, Depart (Job 21:14), and they therefore do not retain God in their knowledge because it thwarts and contradicts their lusts; they do not like it. In their knowledge - en epignōsei. There is a difference between gnōsis and epignōsis, the knowledge and the acknowledgement of God; the pagans knew God, but did not, would not, acknowledge him.

[2.]Answerable to this wilfulness of theirs, in gainsaying the truth, God gave them over to a wilfulness in the grossest sins, here called a reprobate mind - eis adokimon noun, a mind void of all sense and judgment to discern things that differ, so that they could not distinguish their right hand from their left in spiritual things. See whither a course of sin leads, and into what a gulf it plunges the sinner at last; hither fleshly lusts have a direct tendency. Eyes full of adultery cannot cease from sin, Pe2 2:14. This reprobate mind was a blind scared conscience, past feeling, Eph 4:19. When the judgment is once reconciled to sin, the man is in the suburbs of hell. At first Pharaoh hardened his heart, but afterwards God hardened Pharaoh's heart. Thus wilful hardness is justly punished with judicial hardness. - To do those things which are not convenient. This phrase may seem to bespeak a diminutive evil, but here it is expressive of the grossest enormities; things that are not agreeable to men, but contradict the very light and law of nature. And here he subjoins a black list of those unbecoming things which the Gentiles were guilty of, being delivered up to a reprobate mind. No wickedness so heinous, so contrary to the light of nature, to the law of nations, and to all the interests of mankind, but a reprobate mind will comply with it. By the histories of those times, especially the accounts we have of the then prevailing dispositions and practices of the Romans when the ancient virtue of that commonwealth was so degenerated, it appears that these sins here mentioned were then and there reigning national sins. No fewer than twenty-three several sorts of sins and sinners are here specified, Rom 1:29-31. Here the devil's seat is; his name is legion, for they are many. It was time to have the gospel preached among them, for the world had need of reformation.

First, Sins against the first table: Haters of God. Here is the devil in his own colours, sin appearing sin. Could it be imagined that rational creatures should hate the chief good, and depending creatures abhor the fountain of their being? And yet so it is. Every sin has in it a hatred of God; but some sinners are more open and avowed enemies to him than others, Zac 11:8. Proud men and boasters cope with God himself, and put those crowns upon their own heads which must be cast before his throne.

Secondly, Sins against the second table. These are especially mentioned, because in these things they had a clearer light. In general here is a charge of unrighteousness. This is put first, for every sin is unrighteousness; it is withholding that which is due, perverting that which is right; it is especially put for second-table sins, doing as we would not be done by. Against the fifth commandment: Disobedient to parents, and without natural affection - astorgous, that is parents unkind and cruel to their children. Thus, when duty fails on one side, it commonly fails on the other. Disobedient children are justly punished with unnatural parents; and, on the contrary, unnatural parents with disobedient children. Against the sixth commandment: Wickedness (doing mischief for mischief's sake), maliciousness, envy, murder, debate (eridos - contention), malignity, despiteful, implacable, unmerciful; all expressions of that hatred of our brother which is heart-murder. Against the seventh commandment: Fornication; he mentions no more, having spoken before of other uncleannesses. Against the eighth commandment: Unrighteousness, covetousness. Against the ninth commandment: Deceit, whisperers, back-biters, covenant-breakers, lying and slandering. Here are two generals not before mentioned - inventors of evil things, and without understanding; wise to do evil, and yet having no knowledge to do good. The more deliberate and politic sinners are in inventing evil things, the greater is their sin: so quick of invention in sin, and yet without understanding (stark fools) in the thoughts of God. Here is enough to humble us all, in the sense of our original corruption; for every heart by nature has in it the seed and spawn of all these sins. In the close he mentions the aggravations of the sins, Rom 1:32. 1. They knew the judgment of God; that is, (1.) They knew the law. The judgment of God is that which his justice requires, which, because he is just, he judgeth meet to be done. (2.) They knew the penalty; so it is explained here: They knew that those who commit such things were worthy of death, eternal death; their own consciences could not but suggest this to them, and yet they ventured upon it. It is a great aggravation of sin when it is committed against knowledge (Jam 4:17), especially against the knowledge of the judgment of God. It is daring presumption to run upon the sword's point. It argues the heart much hardened, and very resolutely set upon sin. 2. They not only do the same, but have pleasure in those that do them. The violence of some present temptation may hurry a man into the commission of such sins himself in which the vitiated appetite may take a pleasure; but to be pleased with other people's sins is to love sin for sin's sake: it is joining in a confederacy for the devil's kingdom and interest. Suneudokousi: they do not only commit sin, but they defend and justify it, and encourage others to do the like. Our own sins are much aggravated by our concurrence with, and complacency in, the sins of others.

Now lay all this together, and then say whether the Gentile world, lying under so much guilt and corruption, could be justified before God by any works of their own.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 19–32. Public domain.
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Clement of AlexandriaAD 215
The Stromata Book 1
In the same way as Paul, prophecy upbraids the people with not understanding the law. "Destruction and misery are in their ways, and the way of peace have they not known." "There is no fear of God before their eyes." "Professing themselves wise, they became fools."
Lucius Caecilius Firmianus LactantiusAD 325
The Divine Institutes Book 2, Chapter III
But (as I have said) pardon may be granted to those who are ignorant and do not own themselves to be wise; but it cannot be extended to those who, while they profess wisdom, rather exhibit folly. I am not, indeed, so unjust as to imagine that they could divine, so that they might find out the truth by themselves; for I acknowledge that this is impossible. But I require from them that which they were able to perform by reason itself. For they would act more prudently, if they both understood that some form of religion is true, and if, while they attacked false religions, they openly proclaimed that men were not in possession of that which is true.
AmbrosiasterAD 384
COMMENTARY ON PAUL’S EPISTLES
They imagined that they were wise because they thought they had explored the natural sciences, investigating the courses of the stars and the quantities of the elements, while rejecting the God who made them. Therefore they are fools, for if these things are worthy of praise, how much more is their Creator!
John ChrysostomAD 407
Homily on Romans 3
For having some great conceit of themselves, and not enduring to go the way which God had commanded them, they were plunged into the reasonings of senselessness. And then to show and give in outline, what a rueful surge it was, and how destitute of excuse, he goes on to say,
PelagiusAD 418
PELAGIUS’S COMMENTARY ON ROMANS
They thought they were wise because they had “discovered” how the invisible God can be honored by means of a visible idol!
Augustine of HippoAD 430
ON FREE WILL 24.72
It is pride that turns man away from wisdom, and folly is the consequence of turning away from wisdom.
Theodoret of CyrusAD 458
INTERPRETATION OF THE LETTER TO THE ROMANS
They increased their guilt by their claim, for in calling themselves wise they showed that in fact they were fools.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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