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Translation
King James Version
The voice of one crying in the wilderness, Prepare ye the way of the Lord, make his paths straight.
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KJV (with Strong's)
The voice G5456 of one crying G994 in G1722 the wilderness G2048, Prepare ye G2090 the way G3598 of the Lord G2962, make G4160 his G846 paths G5147 straight G2117.
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Complete Jewish Bible
"The voice of someone crying out: `In the desert prepare the way for ADONAI! Make straight paths for him!'"
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Berean Standard Bible
“A voice of one calling in the wilderness, ‘Prepare the way for the Lord, make straight paths for Him.’”
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American Standard Version
The voice of one crying in the wilderness, Make ye ready the way of the Lord, Make his paths straight;
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World English Bible Messianic
The voice of one crying in the wilderness, ‘Make ready the way of the Lord! Make his paths straight!’”
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Geneva Bible (1599)
The voyce of him that cryeth in the wildernesse is, Prepare the way of the Lord: make his paths straight.
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Young's Literal Translation
`A voice of one calling in the wilderness, Prepare ye the way of the Lord, straight make ye his paths,' --
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In the KJVVerse 24,219 of 31,102

Study This Verse

SUMMARY

Mark 1:3 introduces John the Baptist as the prophetic forerunner of Jesus Christ, echoing the ancient words of Isaiah. This verse powerfully establishes John's identity and mission: to serve as a solitary voice proclaiming a message of preparation in the desolate wilderness, urging people to clear the spiritual and moral obstacles in their lives to welcome the imminent arrival of the Lord. It sets the foundational tone for Mark's Gospel, immediately linking the coming of Jesus to God's long-foretold redemptive plan.

CONTEXT

  • Literary Context: Mark's Gospel opens with a bold declaration: "The beginning of the gospel of Jesus Christ, the Son of God" Mark 1:1. Immediately following this, Mark grounds his narrative in Old Testament prophecy, specifically quoting from Isaiah 40:3 (and implicitly Malachi 3:1, though only Isaiah is explicitly cited by Mark). This rapid transition from declaration to prophecy underscores the divine origin and preordained nature of Jesus' advent. Mark 1:3 acts as the scriptural justification for the ministry of John the Baptist, whom Mark introduces in the subsequent verses as the one fulfilling this very prophecy, baptizing and preaching repentance in the wilderness Mark 1:4. The verse thus serves as a critical bridge, connecting God's ancient promises with their unfolding reality in the person and work of John, paving the way for Jesus.

  • Historical & Cultural Context: The imagery of "preparing the way" and "making paths straight" in Mark 1:3 draws directly from ancient Near Eastern royal customs. When a king or dignitary was expected to travel, especially through rugged terrain, heralds would be sent ahead to announce his coming, and laborers would literally clear obstacles, fill in valleys, level hills, and straighten winding roads to facilitate a smooth and grand procession. This was a physical act of preparation for a significant arrival. Spiritually, this metaphor would have resonated with a Jewish audience familiar with the idea of God's coming (theophany) and the need for Israel to be prepared to receive Him. The "wilderness" (Greek: erēmos) was also a significant historical and spiritual location for Israel, recalling the Exodus and the forty years of wandering, a place of purification, testing, and divine revelation, making it a fitting backdrop for a new prophetic movement.

  • Key Themes: Mark 1:3 contributes significantly to several overarching themes in Mark and the broader biblical narrative. Firstly, it highlights Prophetic Fulfillment, demonstrating that John's ministry and Jesus' subsequent arrival are not random events but the culmination of God's long-standing promises, particularly those found in Isaiah 40 and Malachi 3. Secondly, the verse emphasizes Divine Preparation, asserting that God actively prepares humanity for His redemptive work, both through prophetic messengers like John and through the spiritual readiness required from individuals. Thirdly, it establishes the Sovereignty of God, as the unfolding events are clearly orchestrated according to His eternal plan. Finally, it underscores the Urgency of Response, as the call to "prepare" is an active command, demanding a radical change of heart and life (repentance) in anticipation of the Lord's coming, a theme further developed in Mark 1:4-5.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • voice (Greek, phōnḗ, G5456): This word denotes a sound, tone, or articulate utterance. In the context of Mark 1:3, it specifically refers to the audible message proclaimed by John the Baptist. It emphasizes that John is not the message itself, but merely the instrument through which the message is delivered, highlighting his role as a messenger rather than the Messiah.
  • wilderness (Greek, érēmos, G2048): Meaning lonesome, waste, or desolate, this term refers to the uninhabited desert region where John conducted his ministry. The wilderness serves as a symbolic location, recalling Israel's past experiences of divine encounter and testing, and signifying a place apart from societal norms, where God's voice can be heard clearly and new beginnings can take root.
  • Lord (Greek, kýrios, G2962): This powerful title signifies supreme authority, mastery, and control. In the Septuagint (Greek Old Testament), kýrios is frequently used to translate the Hebrew divine name YHWH. Mark's application of this title to the one for whom John prepares the way unequivocally identifies Jesus as the divine "Lord," asserting His inherent deity and authority from the very outset of the Gospel.

Verse Breakdown

  • "The voice of one crying in the wilderness,": This phrase immediately identifies the speaker as a prophetic figure, reminiscent of Old Testament prophets who often ministered in desolate places. The "voice" signifies a messenger, not the message's source, emphasizing John's subordinate role to the one he announces. The "wilderness" setting highlights the unconventional nature of John's ministry and its separation from established religious institutions, echoing the prophetic tradition of encountering God outside conventional spaces.
  • "Prepare ye the way of the Lord,": This is a direct command, calling for active preparation. "The way" (Greek: hodós) refers to a road or path, metaphorically signifying the spiritual and moral conditions necessary to receive the Lord. The imperative "prepare" (Greek: hetoimázō) implies making ready, removing obstacles, and clearing a path for a significant arrival. The object of this preparation is "the Lord," a clear and significant title that, within the context of the Isaiah prophecy, refers to God Himself, and in Mark's narrative, points directly to Jesus.
  • "make his paths straight.": This clause reiterates and amplifies the previous command, using parallel imagery. "Paths" (Greek: tríbos) refers to a worn track or rut, suggesting the established patterns of life. "Straight" (Greek: euthýs) means level, direct, or true. This imagery calls for a moral and spiritual alignment, removing the "crookedness" of sin, pride, and disobedience, ensuring that one's life is aligned with God's will and ready to welcome His presence and work.

Literary Devices

Mark 1:3 is rich in literary devices that enhance its theological impact. The most prominent is Quotation/Allusion, as the verse is a direct citation from Isaiah 40:3. This immediate appeal to ancient prophecy establishes the divine authority and preordained nature of the events unfolding. Metaphor and Imagery are central to the verse's meaning, particularly in the phrases "prepare the way" and "make his paths straight." These are not literal road-building instructions but powerful spiritual metaphors for repentance, moral transformation, and the removal of obstacles (sins, pride, self-sufficiency) that hinder a relationship with God. The Symbolism of the "wilderness" is also significant, representing a place of divine encounter, spiritual purification, and new beginnings, reminiscent of Israel's journey from Egypt. Finally, the verse employs Foreshadowing, as John's ministry is presented as a direct precursor to the greater one who is to come, building anticipation for the arrival of Jesus Christ.

THEOLOGICAL AND THEMATIC CONNECTIONS

Mark 1:3 serves as a theological cornerstone, linking the Old Testament prophetic tradition with the dawn of the New Covenant. It establishes the continuity of God's redemptive plan, demonstrating that Jesus' arrival was not a spontaneous event but the fulfillment of long-standing divine promises. The call to "prepare the way" is a timeless theological principle, emphasizing humanity's responsibility to respond to God's initiative through repentance and a transformed life. This preparation is not merely external but deeply internal, involving a straightening of one's moral and spiritual "paths" to align with God's righteousness. The identification of Jesus as "the Lord" for whom the way is prepared subtly but powerfully asserts His divine identity, placing Him in continuity with Yahweh of the Old Testament and setting the stage for His authoritative ministry.

  • Isaiah 40:3 - The primary Old Testament prophecy directly quoted in Mark 1:3, foretelling a voice in the wilderness preparing the way for the Lord.
  • Malachi 3:1 - Another key prophecy regarding a messenger sent before the Lord, which the New Testament also associates with John the Baptist's preparatory ministry.
  • Luke 3:4-6 - Luke's parallel account of John's ministry, which quotes Isaiah 40:4-5, expanding on the idea of making paths straight and seeing God's salvation.

REFLECTION AND APPLICATION

Mark 1:3, though concise, issues a profound call to action that resonates deeply with believers today. Just as John the Baptist urged his contemporaries to prepare for the first coming of the Lord, so too are we called to cultivate a state of readiness for God's ongoing work in our lives and for Christ's promised return. This preparation is an active, ongoing process, requiring us to honestly examine the "paths" of our lives—our attitudes, habits, priorities, and relationships. Are there areas of sin, pride, unforgiveness, or complacency that create "crooked" or "rough" places, obstructing our full surrender and communion with God? To "make his paths straight" means to actively repent, confessing our shortcomings, turning away from anything that hinders our relationship with Him, and intentionally aligning our lives with His righteous will and purposes. It is a call to clear the clutter of worldly distractions and self-reliance, making ample room for the Holy Spirit to work freely within us, transforming us into Christ's likeness and enabling us to participate in His mission in the world.

Questions for Reflection

  • What "crooked paths" or "rough places" in my life currently need to be made straight to better receive the Lord's presence and guidance?
  • How can I actively prepare my heart and mind daily to be more receptive to God's Word and His Spirit?
  • In what ways am I, like John, called to be a "voice" preparing the way for Christ in my sphere of influence, pointing others to Him?

FAQ

What is the significance of the "wilderness" in Mark 1:3?
Answer: The "wilderness" (Greek: érēmos) in Mark 1:3 is highly significant. Historically, it recalls Israel's forty years of wandering in the desert after the Exodus, a period of testing, purification, and direct encounter with God. Prophetically, it often served as a place where God spoke to His prophets (e.g., Elijah). For John the Baptist, the wilderness signifies a break from established religious institutions and a return to a more primal, uncorrupted setting for divine revelation. It emphasizes the radical nature of his message and ministry, a place where one is stripped of distractions and forced to confront their spiritual state, making it an ideal location for a call to repentance and preparation for the Lord's coming.

How does Mark 1:3 connect to Old Testament prophecy?
Answer: Mark 1:3 is a direct quotation from Isaiah 40:3. This connection is crucial because it immediately establishes the divine authority and preordained nature of John the Baptist's ministry and Jesus' subsequent arrival. By quoting Isaiah, Mark demonstrates that God's plan of salvation, stretching back centuries, is now unfolding. It frames John's role as the prophesied forerunner, the "voice" preparing the way for the "Lord," thereby linking the New Testament events inextricably to God's ancient promises and covenant faithfulness.

CHRIST-CENTERED FULFILLMENT

Mark 1:3, though speaking of John the Baptist's preparatory ministry, finds its ultimate fulfillment in Jesus Christ. John's role was to "prepare the way of the Lord," and Jesus is unequivocally revealed as that very Lord. He is the one for whom the paths were to be made straight, not merely a human king, but the divine Son of God, the one who embodies the very presence of God among humanity. Jesus Himself is the ultimate "straight path" to God, declaring, "I am the way, and the truth, and the life. No one comes to the Father except through me" John 14:6. Through His perfect life, atoning death on the cross, and victorious resurrection, Jesus cleared the ultimate obstacle—sin—that separated humanity from God, making the way perfectly straight and accessible. He is the one who truly "makes straight" our crooked lives, not merely through a call to repentance, but by providing the power for transformation through His Spirit Romans 8:3-4. Thus, John's cry in the wilderness points directly to the one who is the Way, the one who fulfills all prophecy, and the one who brings humanity into a reconciled relationship with the Father 2 Corinthians 5:18-19.

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Commentary on Mark 1 verses 1–8

I. II. Main points1. 2. Sub-points

We may observe here,

I. What the New Testament is - the divine testament, to which we adhere above all that is human; the new testament, which we advance above that which was old. It is the gospel of Jesus Christ the Son of God, Mar 1:1. 1. It is gospel; it is God's word, and is faithful and true; see Rev 19:9; Rev 21:5; Rev 22:6. It is a good word, and well worthy of all acceptation; it brings us glad tidings. 2. It is the gospel of Jesus Christ, the anointed Saviour, the Messiah promised and expected. The foregoing gospel began with the generation of Jesus Christ - that was but preliminary, this comes immediately to the business - the gospel of Christ. It is called his, not only because he is the Author of it, and it comes from him, but because he is the Subject of it, and it treats wholly concerning him. 3. This Jesus is the Son of God. That truth is the foundation on which the gospel is built, and which it is written to demonstrate; for is Jesus be not the Son of God, our faith is vain.

II. What the reference of the New Testament is to the Old, and its coherence with it. The gospel of Jesus Christ begins, and so we shall find it goes on, just as it is written in the prophets (Mar 1:2); for it saith no other things than those which the prophets and Moses said should come (Act 26:22), which was most proper and powerful for the conviction of the Jews, who believed the Old Testament prophets to be sent of God and ought to have evidenced that they did so by welcoming the accomplishment of their prophecies in its season; but it is of use to us all, for the confirmation of our faith both in the Old Testament and in the New, for the exact harmony that there is between both shows that they both have the same divine original.

Quotations are here borrowed from two prophecies - that of Isaiah, which was the longest, and that of Malachi, which was the latest (and there were above three hundred years between them), both of whom spoke to the same purport concerning the beginning of the gospel of Jesus Christ, in the ministry of John.

1.Malachi, in whom we had the Old Testament farewell, spoke very plainly (Mal 3:1) concerning John Baptist, who was to give the New Testament welcome. Behold, I send my messenger before thy face, Mar 1:2. Christ himself had taken notice of this, and applied it to John (Mat 11:10), who was God's messenger, sent to prepare Christ's way.

2.Isaiah, the most evangelical of all the prophets, begins the evangelical part of his prophecy with this, which points to the beginning of the gospel of Christ (Isa 40:3); The voice of him that crieth in the wilderness, Mar 1:3. Matthew had taken notice of this, and applied it to John, Mat 3:3. But from these two put together here, we may observe, (1.) That Christ, in his gospel, comes among us, bringing with him a treasure of grace, and a sceptre of government. (2.) Such is the corruption of the world, that there is something to do to make room for him, and to remove that which gives not only obstruction, but opposition to his progress. (3.) When God sent his Son into the world, he took care, and when he sends him into the heart, he takes care, effectual care, to prepare his way before him; for the designs of his grace shall not be frustrated; nor may any expect the comforts of that grace, but such as, by conviction of sin and humiliation for it, are prepared for those comforts, and disposed to receive them. (4.) When the paths that were crooked, are made straight (the mistakes of the judgment rectified, and the crooked ways of the affections), then way is made for Christ's comforts. (5.) It is in a wilderness, for such this world is, that Christ's way is prepared, and theirs that follow him, like that which Israel passed through to Canaan. (6.) The messengers of conviction and terror, that come to prepare Christ's way, are God's messengers, whom he sends and will own, and must be received as such. (7.) They that are sent to prepare the way of the Lord, in such a vast howling wilderness as this is, have need to cry aloud, and not spare, and to lift up their voice like a trumpet.

III. What the beginning of the New Testament was. The gospel began in John Baptist; for the law and the prophets were, until John, the only divine revelation, but then the kingdom of God began to be preached, Luk 16:16. Peter begins from the baptism of John, Act 1:22. The gospel did not begin so soon as the birth of Christ, for he took time to increase in wisdom and stature, not so late as his entering upon his public ministry, but half a year before, when John began to preach the same doctrine that Christ afterward preached. His baptism was the dawning of the gospel day; for,

1.In John's way of living there was the beginning of a gospel spirit; for it bespoke great self-denial, mortification of the flesh, a holy contempt of the world, and nonconformity to it, which may truly be called the beginning of the gospel of Christ in any soul, Mar 1:6. He was clothed with camels' hair, not with soft raiment; was girt, not with a golden, but with a leathern girdle; and, in contempt of dainties and delicate things, his meat was locusts and wild honey. Note, The more we sit loose to the body, and live above the world, the better we are prepared for Jesus Christ.

2.In John's preaching and baptizing there was the beginning of the gospel doctrines and ordinances, and the first fruits of them. (1.) He preached the remission of sins, which is the great gospel privilege; showed people their need of it, that they were undone without it, and that it might be obtained. (2.) He preached repentance, in order to it; he told people that there must be a renovation of their hearts and a reformation of their lives, that they must forsake their sins and turn to God, and upon those terms and no other, their sins should be forgiven. Repentance for the remission of sins, was what the apostles were commissioned to preach to all nations, Luk 24:27. (3.) He preached Christ, and directed his hearers to expect him speedily to appear, and to expect great things from him. The preaching of Christ is pure gospel, and that was John Baptist's preaching, Mar 1:7, Mar 1:8. Like a true gospel minister, he preaches, [1.] The great pre-eminence Christ is advanced to; so high, so great, is Christ, that John, though one of the greatest that was born of women, thinks himself unworthy to be employed in the meanest office about him, even to stoop down, and untie his shoes. Thus industrious is he to give honour to him, and to bring others to do so too. [2.] The great power Christ is invested with; He comes after me in time, but he is mightier than I, mightier than the mighty ones of the earth, for he is able to baptize with the Holy Ghost; he can give the Spirit of God, and by him govern the spirits of men. [3.] The great promise Christ makes in his gospel to those who have repented, and have had their sins forgiven them; They shall be baptized with the Holy Ghost, shall be purified by his graces, and refreshed by his comforts. And, lastly, All those who received his doctrine, and submitted to his institution, he baptized with water, as the manner of the Jews was to admit proselytes, in token of their cleansing themselves by repentance and reformation (which were the duties required), and of God's cleansing them both by remission and by sanctification, which were the blessings promised. Now this was afterward to be advanced into a gospel ordinance, which John's using it was a preface to.

3.In the success of John's preaching, and the disciples he admitted by baptism, there was the beginning of a gospel church. He baptized in the wilderness, and declined going into the cities; but there went out unto him all the land of Judea, and they of Jerusalem, inhabitants both of city and country, families of them, and were all baptized of him. They entered themselves his disciples, and bound themselves to his discipline; in token of which, they confessed their sins; he admitted them his disciples, in token of which, he baptized them. Here were the stamina of the gospel church, the dew of its youth from the womb of the morning, Psa 110:3. Many of these afterward became followers of Christ, and preachers of his gospel, and this grain of mustard-seed became a tree.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 1–8. Public domain.
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Pseudo-Augustine (as quoted by Aquinas, AD 1274)
Catena Aurea by Aquinas
(Quæst. nov. et vet. Test. lvii.) For knowing that all things are to be referred to their author, he has brought these sayings back to Isaiah, who was the first to intimate the sense. Lastly, after the words of Malachi, he immediately subjoins, The voice of one crying in the wilderness, in order to connect the words of each prophet, belonging as they do to one meaning, under the person of the elder prophet.
Pseudo-Jerome (as quoted by Aquinas, AD 1274)
Catena Aurea by Aquinas
Or, the way of the Lord, by which He comes into men, is penitence, by which God comes down to us, and we mount up to Him. And for this reason the beginning of John's preaching was, Repent ye.

But it is called the voice of one crying, for we are wont to use a cry to deaf persons, and to those afar off, or when we are indignant, all which things we know applied to the Jews; for salvation is far from the wicked, and they stopped their ears like deaf adders, and deserved to hear indignation, and wrath, and tribulation from Christ.

Or else the voice and the cry is in the desert, because they were deserted by the Spirit of God, as a house empty, and swept out; deserted also by prophet, priest, and king.

Or else, Prepare ye the way of the Lord, that is, act out repentance and preach it; make his paths straight, that walking in the royal road, we may love our neighbours as ourselves, and ourselves as our neighbours. For he who loves himself, and loves not his neighbour, turns aside to the right; for many act well, and do not correct their neighbour well, as Eli. He, on the other hand, who, hating himself, loves his neighbour, turns aside to the left; for many, for instance, rebuke well, but act not well themselves, as did the Scribes and Pharisees. Paths are mentioned after the way, because moral commands are laid open after penitence.
Origen of AlexandriaAD 253
COMMENTARY ON JOHN 6.24
Mark took two prophecies spoken in different places by two prophets and conflated them into one, so as to declare: “As it is written in Isaiah the Prophet …” “The voice of one crying in the wilderness,” which is indeed recorded immediately after the narrative about Hezekiah’s recovery from his sickness. This is then conflated with “Behold I send my messenger to prepare the way before me,” from Malachi. Both John and Mark compress in various ways the quotation from Isaiah, Mark by reading “His paths” for “the paths of our God” and by omitting “before me.”
Victorinus of PettauAD 304
Commentary on the Apocalypse of the Blessed John, From the Fourth Chapter
"The first living creature was like to a lion, and the second was like to a calf, and the third had a face like to a man, and the fourth was like to a flying eagle; and they had six wings, and round about and within they were full of eyes; and they had no rest, saying, Holy, holy, holy, Lord Omnipotent. And the four and twenty elders, failing down before the throne, adored God." The four and twenty elders arethe twenty-four books of the prophets and of the law, which give testimonies of the judgment. Moreover, also, they are the twenty-four fathers-twelve apostles and twelve patriarchs.And in that the living creatures are different in appearance, this is the reason: the living creature like to a lion designates Mark, in whom is heard the voice of the lion roaring in the desert. And in the figure of a man, Matthew strives to declareto us the genealogy of Mary, from whom Christ took flesh. Therefore, in enumerating from Abraham to David, and thence to Joseph, he spoke of Him as if of a man: therefore his announcement sets forth the image of a man. Luke, in narrating the priesthood of Zacharias as he offers a sacrifice for the people, and the angel that appears to him with respect of the priesthood, and the victim in the same description bore the likeness of a calf. John the evangelist, like to an eagle hastening on uplifted wings to greater heights, argues about the Word of God. Mark, therefore, as an evangelist thus beginning, "The beginning of the Gospel of Jesus Christ, as it is written in Isaiah the prophet; " The voice of one crying in the wilderness," -has the effigy of a lion. And Matthew, "The hook of the generation of Jesus Christ, the son of David, the son of Abraham: " this is the form of a man. But Luke said, "There was a priest, by name Zachariah, of the course of Abia, and his wife was of the daughters of Aaron: " this is the likeness of a calf. But John, when he begins, "In the beginning was the Word, and the Word was with God, and the Word was God," sets forth the likeness of a flying eagle. Moreover, not only do the evangelists express their four similitudes in their respective openings of the Gospels, but also the Word itself of God the Father Omnipotent, which is His Son our Lord Jesus Christ, bears the same likeness in the time of His advent. When He preaches to us, He is, as it were, a lion and a lion's whelp. And when for man's salvation He was made man to overcome death, and to set all men free, and that He offered Himself a victim to the Father on our behalf, He was called a calf. And that He overcame death and ascended into the heavens, extending His wings and protecting His people, He was named a flying eagle. Therefore these announcements, although they are four, yet are one, because it proceeded from one mouth. Even as the river in paradise, although it is one, was divided into four heads. Moreover, that for the announcement of the New Testament those bring creatures had eyes within and without, shows the spiritual providence which both looks into the secrets of the heart, and beholds the things which are coming after that are within and without.
Hilary of Poitiers (as quoted by Aquinas, AD 1274)AD 367
Catena Aurea by Aquinas
(de Trin. iii. 11) He has testified, that Christ was the Son of God, not in name only, but by His own proper nature. We are the sons of God, but He is not a son as we are; for He is the very and proper Son, by origin, not by adoption; in truth, not in name; by birth, not by creation.
JeromeAD 420
Hierom. ad Pammach, Epist 57: But this is not written in Isaiah, but in Malachi, the last of the twelve prophets. The Evangelist therefore, taking parts of two prophecies, has put them down as spoken by Isaiah, and refers them here toone passage, without mentioning, however, by whom it is said, “Behold, I send mine angel.”.
By Malachi, therefore, the voice of the Holy Spirit resounds to the Father concerning the Son, who is the countenance of the Father by which He has been known.
Or, “the way of the Lord, "by which He comes into men, in penitence, by which God comes down to us, and we mount up to Him. And for this reason the beginning of John’s preaching was, "Repent ye.”.
But it is called “the voice of one crying,” for we are wont to use a cry to deaf persons, and to those afar off, or when we are indignant, all which things we know applied to the Jews; for “salvation is far from the wicked,” and they “stopped their ears like deaf adders,” and deserved to hear “indignation, and wrath, and tribulation” fromChrist.The word of prophecy also shows, that besides the wilderness, which was pointed out by Moses, where he made paths, there was another wilderness, in which it proclaimed that the salvation of Christ was present.
Or else the voice and thecry is in the desert, because they were deserted by the Spirit of God, as ahouse empty, and swept out; deserted also by prophet, priest, and king.
Or else, “Prepare ye the way of the Lord,” that is, act out repentance and preach it; “make his paths straight,” that walking in the royal road, we may love our neighbours as ourselves, and ourselves as our neighbours. For he who loves himself, and loves not his neighbour, turns aside to the right; for many act well, and do not correct their neighbour well, as Eli. He, on the other hand, who, hating himself, loves his neighbour, turns aside to the left; for many, for instance, rebuke well, but act not well themselves, as did the Scribes and Pharisees. "Paths” are mentioned after the “way "because moral commands are laid open after penitence.
Jerome (as quoted by Aquinas, AD 1274)AD 420
Catena Aurea by Aquinas
(ad Pammach. Epist. 57) But this is not written in Isaiah, but in Malachi, the last of the twelve prophets.

By Malachi, therefore, the voice Πνεύμκτος Ἅγιου of the Holy Spirit resounds to the Father concerning the Son, who is the countenance of the Father by which He has been known.
JeromeAD 420
LETTER 57 TO PAMMACHIUS 9
The quotation is made up from two prophets, Malachi and Isaiah. From the first part: “Behold I send my messenger to prepare the way before me,” occurs at the close of Malachi. But the second part: “The voice of one crying,” etc., we read in Isaiah. On what ground then has Mark in the very beginning of his book set the words: “As it is written in the prophet Isaiah, Behold I send my messenger,” when, as we have said, it is [in part] not written in Isaiah at all, but in Malachi, the last of the twelve prophets? Let ignorant presumption solve this nice question if it can. I will ask pardon for being in the wrong.… The apostle has not rendered his original word for word, but using a paraphrase, he has given the sense in different terms.
Augustine of HippoAD 430
Quaest. nov. et vet. Test.lvii: For knowing that all things are to be referred to their author, he has brought these sayings back to Isaiah, who was the first to intimate the sense. Lastly, after the words of Malachi, he immediately subjoins, “The voice of one crying in the wilderness,” in order to connect the words of each prophet, belonging as they do to one meaning, under the person of the elder prophet.
Maximus of TurinAD 465
SERMON 6
Voice and crying go together: the voice preaches faith; the cry calls for repentance; the voice, comfort; the cry, danger; the voice sings mercy; the cry announces judgment.
Pseudo-Chrysostom (as quoted by Aquinas, AD 1274)AD 500
Catena Aurea by Aquinas
(Vict. Ant. c. Cat. in Marc.) But it may be said that it is a mistake of the writer. Otherwise it may be said, that he has compressed into one, two prophecies delivered in different places by two prophets; for in the prophet Isaiah it is written after the story of Hezekiah, The voice of one crying in the wilderness; but in Malachi, Behold, I send mine angel. The Evangelist therefore, taking parts of two prophecies, has put them down as spoken by Isaiah, and refers them here to one passage, without mentioning, however, by whom it is said, Behold, I send mine angel.

(Vict. Ant. e. Cat. in Marc.) But the prophecy, by saying, In the wilderness, plainly shows that the divine teaching was not in Jerusalem, but in the wilderness, which was fulfilled to the letter by John the Baptist in the wilderness of Jordan, preaching the healthful appearing of the Word of God. (non occ.). The word of prophecy also shows, that besides the wilderness, which was pointed out by Moses, where he made paths, there was another wilderness, in which it proclaimed that the salvation of Christ was present.
Gregory the DialogistAD 604
Forty Gospel Homilies, Homily 7
"I am the voice of one crying in the wilderness: Make straight the way of the Lord, as Isaiah the prophet said." You know, dearest brothers, that the only-begotten Son is called the Word of the Father, as John testifies when he says: "In the beginning was the Word, and the Word was with God, and the Word was God." And from your own manner of speaking you recognize that the voice sounds first, so that the word may afterward be heard. Therefore John asserts that he is the voice, because he precedes the Word. And so, going before the coming of the Lord, he is called a voice, because through his ministry the Word of the Father is heard by men. He also cries out in the wilderness, because he announces the comfort of the Redeemer to abandoned and forsaken Judea. But what he cries out he indicates when he adds: "Make straight the way of the Lord." The way of the Lord is made straight to the heart when the word of truth is humbly heard. The way of the Lord is made straight to the heart when one's life is prepared according to his commandment.
Gregory the DialogistAD 604
Forty Gospel Homilies, Homily 20
As it is written in the book of the words of Isaiah the prophet: The voice of one crying in the wilderness, Prepare the way of the Lord, make his paths straight. Indeed, the same John the Baptist, when asked who he was, answered, saying: I am the voice of one crying in the wilderness. He, as was said by us before, was called a voice by the prophet because he preceded the Word. But what he cried out is revealed when it is added: Prepare the way of the Lord, make his paths straight. Everyone who preaches right faith and good works, what else does he do but prepare a way for the coming Lord into the hearts of his hearers? So that the power of grace may penetrate, so that the light of truth may illuminate, so that he may make straight paths for God, while he forms pure thoughts in the mind through the word of good preaching.
Bede (as quoted by Aquinas, AD 1274)AD 735
Catena Aurea by Aquinas
(ubi sup.) Being about to write his Gospel, Mark rightly puts first the testimonies of the Prophets, that he might notify to all, that what he should write was to be received without scruple of doubt, in that he showed that these things were beforehand foretold by the Prophets. At once, by one and the same beginning of his Gospel, he prepared the Jews, who had received the Law and the Prophets, for receiving the grace of the Gospel, and those sacraments, which their own prophecies had foretold; and he also calls upon the Gentiles, who came to the Lord by publishing of the Gospel, to receive and venerate the authority of the Law and the Prophets; whence he says, As it is written in the prophet Isaiah, Behold, &c.

(ubi sup.) Or otherwise, we must understand, that, although these words are not found in Isaiah, still the sense of them is found in many other places, and most clearly in this which he has subjoined, The voice of one crying in the wilderness. For that which Malachi has called, the angel to be sent before the face of the Lord, to prepare His way, is the same thing as Isaiah has said is to be heard, the voice of one crying in the wilderness, saying, Prepare ye the way of the Lord. But in each sentence alike, the way of the Lord to be prepared is proclaimed. It may be, too, that Isaiah occurred to the mind of Mark, in writing his Gospel, instead of Malachi, as often happens; which he would, however, without doubt correct, at least when reminded by other persons, who might read his work whilst he was yet in the flesh; unless he thought, that, since his memory was then ruled by the Holy Spirit, it was not without a purpose, that the name of one prophet had occurred to him instead of another. For thus whatsoever things the Holy Spirit spoke by the prophets, are implied each to have belonged to all, and all to each.

(ubi sup.) But John is called an angel not by community of nature, according to the heresy of Origena, but by the dignity of his office; for angel in Greek is in Latin, nuntius, (messenger,) by which name that man is rightly called, who was sent by God, that he might bear witness of the light, and announce to the world the Lord, coming in the flesh: since it is evident that all who are priests may by their office of preaching the Gospel be called angels, as the prophet Malachi says, The lips of the priest keep knowledge, and they seek the law at his mouth, because he is the Angel of the Lord of hosts. (Mal. 2:7)

(ubi sup.) But as John might be called an angel, because he went before the face of the Lord by his preaching, so he might also be rightly called a voice, because, by his sound, he preceded the Word of the Lord. Wherefore there follows, The voice of one crying, &c. For it is an acknowledged thing that the Only-Begotten Son is called the Word of the Father, and even we, from having uttered words ourselves, know that the voice sounds first, in order that the word may afterwards be heard.

(ubi sup.) What he cried is revealed, in that which is subjoined, Prepare ye the way of the Lord, make his paths straight. For whosoever preaches a right faith and good works, what else does he but prepare the way for the Lord's coming to the hearts of His hearers, that the power of grace might penetrate these hearts, and the light of truth shine in them? And the paths he makes straight, when he forms pure thoughts in the soul by the word of preaching.
BedeAD 735
On the Gospel of Mark
A voice crying out in the desert: Prepare the way of the Lord, etc. It is clear that the only-begotten Son is called the Word of the Father, as John attests, who says: In the beginning was the Word, and the Word was with God, and the Word was God (John 1). And we know from our speech itself that the voice sounds first, so that the word can be heard afterward. Therefore, John is called a voice by the prophet because the word precedes. Thus, the voice is said to precede the Lord's coming because through his ministry the Word of the Father is heard by men. He also cries out in the desert because he announces the consolation of redemption to the forsaken and desolate Judah. What he cries out, however, is revealed when it is added: Prepare the way of the Lord, make straight his paths. Whoever preaches true faith and good works, what else does he do but prepare the way for the Lord to enter the hearts of the listeners, so that the power of grace may penetrate, the light of truth may shine, and make straight paths for God, by forming pure thoughts in the mind through the word of good preaching? Indeed it must be noted that from the prophetic testimonies which Mark has placed, one is only found in Isaiah, while the other is found in Malachi. Yet the evangelist should not be thought to have erred or been deceitful, who says this was written in Isaiah which Isaiah did not write, but rather it should be understood that even if the words placed from Malachi are not found in Isaiah, the sense of them is found in Isaiah, and in several other places, and more clearly in what he himself added here: A voice crying out in the desert: Prepare the way of the Lord, make straight his paths. For who does not see how great the agreement is in both statements? For what Malachi said, that an angel should be sent before the face of the Lord who would prepare his way, is indeed the same as what Isaiah said, that a voice crying out should be heard in the desert, who said: Prepare the way of the Lord, make straight his paths. Because just as John could rightly be called an angel, because he preceded the face of the Lord by preaching, so he could rightly be called the voice, because he preceded the Word of God by sounding it, as was stated above. But in both statements the way of the Lord is similarly preached to be prepared. Therefore, the evangelist is not mistaken, who writes this said by Isaiah: which even if not in the same words, nevertheless he finds written by him in the same sense. However, it could have happened that in the mind of Mark writing the Gospel, Isaiah occurred instead of Malachi, as happens. But he would without any doubt correct this, at least being admonished by others who could read this while he was still living in the flesh, unless he thought that the name of another prophet occurred to his memory, which was governed by the Holy Spirit, not without reason, because the Lord ordained it to be written thus. But why the Lord ordained it so, that most useful cause should be easily thought of, namely, that it is thus hinted that all the holy prophets spoke by one spirit in wonderful agreement, which is much greater than if all the sayings of all the prophets were spoken by the mouth of one man. And therefore, whatever the Holy Spirit said through them should be undoubtedly accepted, and each one’s words belong to all, and all to each one. Therefore, what has been said through Isaiah is as much Malachi's as Isaiah's, and what has been said through Malachi is as much Isaiah's as Malachi's, what need was there for Mark to correct when reading to himself what name occurred for another? And rather, following the authority of the Holy Spirit, by whom he certainly more than us felt his mind was governed, thus he would leave this written as it is? For the Lord had ordained to instruct him in this way to show us that there is such great harmony in his words among the prophets, that we should most fittingly even attribute what is found said by Malachi to Isaiah.
Theophylact of Ohrid (as quoted by Aquinas, AD 1274)AD 1107
Catena Aurea by Aquinas
The Forerunner of Christ, therefore, is called an angel, on account of his angelic life and lofty reverence. Again, where he says, Before thy face, it is as if he said, Thy messenger is near thee: whence is shown the intimate connection of the Forerunner with Christ; for those walk next to kings, who are their greatest friends. There follows, Who will prepare thy way before thee. For by baptism he prepared the minds of the Jews to receive Christ.

Or, the way is the New Testament, and the paths are the Old, because it is a trodden path. For it was necessary to be prepared for the way, that is, for the New Testament; but it was right that the paths of the Old Testament should be straightened.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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