Bible Verses About Syria: In the time of Abraham it seems to have embraced the region between the rivers Tigris and Euphrates

Then the servant took ten of his master's camels and all kinds of gifts from his master, got up and went to Aram-Naharayim, to Nachor's city.

Yitz'chak was forty years old when he took Rivkah, the daughter of B'tu'el the Arami from Paddan-Aram and sister of Lavan the Arami, to be his wife.