Bible Verses About Syria: In the time of Abraham it seems to have embraced the region between the rivers Tigris and Euphrates

Then the servant took ten of his master’s camels and departed with all manner of good things from his master in hand. And he set out for Nahor’s hometown in Aram-naharaim.

and Isaac was forty years old when he married Rebekah, the daughter of Bethuel the Aramean from Paddan-aram and the sister of Laban the Aramean.