Bible Verses About Syria: In the time of Abraham it seems to have embraced the region between the rivers Tigris and Euphrates

And the servant took ten camels, of the camels of his master, and departed, having all goodly things of his master’s in his hand: and he arose, and went to Mesopotamia, unto the city of Nahor.

and Isaac was forty years old when he took Rebekah, the daughter of Bethuel the Syrian of Paddan-aram, the sister of Laban the Syrian, to be his wife.