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Translation
King James Version
¶ Now when Jesus was in Bethany, in the house of Simon the leper,
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KJV (with Strong's)
Now G1161 when Jesus G2424 was G1096 in G1722 Bethany G963, in G1722 the house G3614 of Simon G4613 the leper G3015,
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Complete Jewish Bible
Yeshua was in Beit-Anyah, at the home of Shim`on, the man who had had tzara'at.
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Berean Standard Bible
While Jesus was in Bethany in the home of Simon the Leper,
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American Standard Version
Now when Jesus was in Bethany, in the house of Simon the leper,
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World English Bible Messianic
Now when Yeshua was in Bethany, in the house of Simon the leper,
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Geneva Bible (1599)
And when Iesus was in Bethania, in the house of Simon the leper,
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Young's Literal Translation
And Jesus having been in Bethany, in the house of Simon the leper,
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All Matthew Sites (Jerusalem)
All Matthew Sites (Jerusalem) View full PDF
Matthew 26:1-16, Matthew 26:17-25, Mark 11:12-26, Mark 11:27-33, Luke 10:38-42, John 12:12-18
Matthew 26:1-16, Matthew 26:17-25, Mark 11:12-26, Mark 11:27-33, Luke 10:38-42, John 12:12-18 View full PDF
The Last Week of Jesus' Life (With Reference Table)
The Last Week of Jesus' Life (With Reference Table) View full PDF

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In the KJVVerse 24,061 of 31,102

Study This Verse

SUMMARY

Matthew 26:6 sets the immediate scene for a profoundly significant event in Jesus' final week before His crucifixion. It places Jesus in Bethany, a village near Jerusalem, within the home of a man identified as Simon the leper. This seemingly simple detail provides crucial context, highlighting Jesus' continued association with the marginalized and establishing the intimate setting for the anointing that prophetically anticipates His impending death and burial.

CONTEXT

  • Literary Context: This verse serves as the immediate prelude to the account of a woman anointing Jesus with expensive perfume, an event recorded in Matthew 26:7-13. It follows Jesus' pronouncement in Matthew 26:2 that the Passover is two days away and He will be crucified, and precedes the conspiracy of the chief priests and elders to seize and kill Him (Matthew 26:3-5). Thus, the setting in Simon's house is not merely a geographical detail but an intimate, domestic space where a profound act of devotion, directly linked to Jesus' sacrificial mission, is about to unfold. The narrative flow emphasizes the juxtaposition of human plots against Jesus with divine preparation for His ultimate purpose.
  • Historical & Cultural Context: Bethany was a small village located on the eastern slope of the Mount of Olives, less than two miles from Jerusalem. It was a frequent retreat for Jesus and His disciples, notably the home of Mary, Martha, and Lazarus (John 11:1). The identification of the host as "Simon the leper" is highly significant. In ancient Israel, leprosy (a broad term encompassing various skin diseases) rendered individuals ceremonially unclean and socially ostracized, requiring them to live apart from the community (Leviticus 13:45-46). The fact that Simon is hosting Jesus implies he had been cleansed, almost certainly by Jesus Himself, as only a healed leper could re-enter society and host guests. This act of hospitality, sharing a meal, was a deeply intimate and culturally significant gesture of acceptance and fellowship in the ancient Near East, underscoring Jesus' radical inclusivity.
  • Key Themes: This verse introduces several key themes that resonate throughout the Passion narrative. Firstly, it highlights Jesus' compassion and radical inclusivity, as He willingly associates with and accepts hospitality from someone who was once an outcast, demonstrating His ministry to the marginalized, a theme evident from His earliest interactions with tax collectors and sinners (Matthew 9:10-13). Secondly, it emphasizes gratitude and devotion, as Simon's hosting likely stems from a profound sense of thankfulness for his healing, setting the stage for the extravagant act of worship by the woman that follows. Thirdly, Bethany itself is a place of refuge and intimacy for Jesus during His final, intense days, contrasting with the hostility he faces in Jerusalem. Finally, the scene subtly introduces the theme of preparation for sacrifice, as the anointing that occurs in this house is explicitly linked by Jesus to His burial, underscoring the divine purpose behind the unfolding events of Matthew 26.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • Now (Greek, dé', G1161): This particle serves as a continuative or adversative conjunction, often translated as "but," "and," or "now." In this context, it functions to smoothly transition the narrative, indicating a shift in location and focus from the previous discussion of the plot against Jesus to the intimate setting in Bethany. It signals the progression of events leading to the Passion.
  • was (Greek, gínomai', G1096): This verb means "to come into being," "to become," or "to happen." While often translated simply as "was," it carries a dynamic sense of occurrence or eventuation. Here, it indicates Jesus' presence in Bethany as an active event, not merely a static state, setting the stage for what "came to pass" in Simon's house. It implies a deliberate arrival and engagement with the setting.
  • leper (Greek, leprós', G3015): Derived from the Greek word for "scaly," this term refers to someone afflicted with leprosy. In Jewish society, a leper was ceremonially unclean and socially ostracized, symbolizing impurity and separation from God and community. The designation "Simon the leper" is crucial because it identifies him by his former condition, yet his ability to host Jesus signifies a miraculous cleansing, likely performed by Jesus, highlighting Jesus' power over disease and His radical embrace of the outcast.

Verse Breakdown

  • "Now when Jesus was in Bethany,": This initial clause establishes the setting in time and place. "Now" () signals a narrative progression, moving from the council's plot to Jesus' immediate circumstances. Bethany, a familiar village to Jesus, signifies a place of temporary respite and intimate fellowship before the ultimate confrontation in Jerusalem. Jesus' presence there is deliberate, part of the divine timetable for His Passion.
  • "in the house of Simon the leper,": This second clause specifies the exact location within Bethany and introduces the host. The phrase "Simon the leper" is profoundly significant. It identifies a man who, by Jewish law, would have been an outcast. His ability to host a meal implies he had been healed of his leprosy, almost certainly by Jesus Himself. This detail immediately underscores Jesus' power to cleanse and restore, and His willingness to associate with and be ministered to by those previously marginalized by society and religious custom. It sets a tone of gratitude and radical inclusion for the events that follow.

Literary Devices

Matthew 26:6, though brief, employs several subtle literary devices. The most prominent is Foreshadowing. The setting in Simon's house in Bethany, immediately preceding the anointing, subtly foreshadows Jesus' impending death and burial. The anointing itself is explicitly stated by Jesus to be "for My burial" (Matthew 26:12), making this verse the literal backdrop for that prophetic act. There is also an element of Irony or Contrast in the identification of Simon as "the leper." While he is named by his past affliction, his current ability to host suggests a profound transformation, likely through Jesus' healing power. This contrast highlights Jesus' redemptive work, transforming an outcast into a host. Finally, the scene itself serves as Symbolism for Jesus' ministry of radical inclusion and cleansing, as the Son of God shares a meal with someone who was once ceremonially unclean, embodying His mission to save and restore those alienated by sin and disease.

THEOLOGICAL AND THEMATIC CONNECTIONS

Matthew 26:6 serves as a powerful testament to Jesus' unwavering commitment to the marginalized and His consistent demonstration of divine power and compassion. The presence of Jesus in the home of "Simon the leper" is a profound theological statement, illustrating that no one is beyond the reach of His healing grace and transforming love. It underscores the New Covenant's emphasis on inner purity over external ritualistic cleanliness, as Jesus willingly enters a space that would have been considered defiling by strict Mosaic standards, yet He brings cleansing and blessing. This act of fellowship with a former outcast sets the stage for an extravagant act of worship, demonstrating that true devotion often flows from a heart deeply touched by divine mercy and restoration.

REFLECTION AND APPLICATION

Matthew 26:6 invites us to consider the profound implications of Jesus' presence in our lives, particularly in our "houses"—our personal spaces, our communities, and our hearts. Simon, once an outcast, was now a host, a testament to the transformative power of an encounter with Christ. This verse challenges us to reflect on our own spiritual "leprosy"—the areas of sin, brokenness, or shame that might make us feel unworthy of God's presence. Just as Jesus entered Simon's home, He desires to enter ours, bringing healing, acceptance, and restoration. It reminds us that true hospitality extends beyond social norms, embracing those whom society might reject, just as Christ embraced Simon. Our gratitude for Christ's work in us should compel us to offer our lives, our resources, and our homes as places where His love and grace can be extended to others, preparing the way for acts of profound worship and service.

Questions for Reflection

  • What "leprosy" in my life or in my community might Jesus be calling me to acknowledge and bring into His presence for healing?
  • How can I extend Christ-like hospitality to those who are marginalized or overlooked in my own context?
  • In what ways does my gratitude for Christ's work in my life manifest in acts of worship or service?

FAQ

Who was Simon the leper, and why is he called "the leper" if he was hosting Jesus?

Answer: Simon the leper is a figure mentioned only in Matthew and Mark's accounts of the anointing at Bethany. He is not mentioned elsewhere in the Gospels. The designation "the leper" strongly suggests that he was a leper whom Jesus had previously healed. In ancient Jewish society, a leper was ceremonially unclean and forbidden from living among healthy people or participating in social gatherings (Leviticus 13:45-46). The fact that he is hosting Jesus and His disciples implies he had been cleansed and restored to society. The title "the leper" likely remained as a way to identify him, much like "Matthew the tax collector" (Matthew 9:9) or "Mary Magdalene" (Mary from Magdala), indicating a significant past or origin. It serves to highlight the transformative power of Jesus, who healed him and restored him to community and dignity.

What is the significance of Bethany in the context of Jesus' final week?

Answer: Bethany held significant importance for Jesus during His final week in Jerusalem. Located just a short distance from the city on the eastern slope of the Mount of Olives, it served as a frequent place of refuge and rest for Jesus and His disciples. It was the home of His dear friends Mary, Martha, and Lazarus, whom He had raised from the dead (John 11:1-44). During the intense days leading up to His crucifixion, Jesus would often teach in the Temple during the day and retreat to Bethany in the evenings (Luke 21:37). This village provided a safe and intimate space away from the escalating hostility in Jerusalem, making it a fitting setting for the private, prophetic act of anointing for His burial.

CHRIST-CENTERED FULFILLMENT

Matthew 26:6, though seemingly a simple geographical and relational detail, profoundly points to the Christ-centered fulfillment of God's redemptive plan. Jesus, the Son of God, willingly enters the "house of Simon the leper," a vivid demonstration of His divine mission to seek and save the lost and outcast. In a society where leprosy symbolized sin and separation from God, Jesus' presence in this home signifies His radical identification with and compassion for humanity's deepest brokenness. He is the Great Physician who not only cleanses physical disease, as He likely did for Simon (Luke 5:12-13), but also purifies the soul from the defilement of sin. This scene directly precedes the anointing for His burial, where a woman's act of devotion prophetically underscores Jesus' ultimate sacrifice. His willingness to be present in such a setting foreshadows His descent into the depths of human suffering and sin on the cross, becoming "sin for us, so that in him we might become the righteousness of God" (2 Corinthians 5:21). Thus, Simon's house, once a place of exclusion, becomes a sanctuary where the Lamb of God is prepared for His atoning work, extending an invitation of cleansing and fellowship to all who, like Simon, have been touched by His transforming grace and are welcomed into the household of God (Ephesians 2:19-22).

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Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers . Public domain.
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Origen of Alexandria (as quoted by Aquinas, AD 1274)AD 253
Catena Aurea by Aquinas
Some one may perhaps think that there are four different women of whom the Evangelists have written, but I rather agree with those who think that they are only three; one of whom Matthew and Mark wrote, one of whom Luke, another of whom John.

Matthew and Mark relate that this was done in the house of Simon the leper; but John says that Jesus came to a house where Lazarus was; and that not Simon, but Mary and Martha served. Further, according to John, six days before the Passover, He came to Bethany where Mary and Martha made Him a supper. But here it is in the house of Simon the leper, and two days before the Passover. And in Matthew and Mark, it is the disciples that have indignation with a good intent; in John, Judas alone with intent to steal; in Luke, no one finds fault.

Oil is throughout Scripture put for the work of mercy, with which the lamp of the word is fed; or for doctrine, the hearing of which sustains the word of faith when once kindled. All with which men anoint is comprehensively called oil; and one kind of oil is unguent, and one kind of unguent is precious. So all righteous acts are called good works; and of good works there is one kind which we do for, or to, men; another which we do for, or to, God. And this likewise that we do for God, in part only advances the good of men, in part, the glory of God. For example, one does a kindness to a man out of feelings of natural righteousness, not for God's sake, as the Gentiles sometime did; such a work is common oil of no fine savour, yet is it acceptable to God, forasmuch, as Peter says in Clement, the good works that the unbelievers do, profit them in this world, but avail not to gain them eternal life in another. They who do the same for God's sake, profit thereby not in this world only but in the next also, and that they do is ointment of good savour. Another sort is that done for the good of men, as alms, and the like. He who does this to Christians, anoints the Lord's feet, for they are the Lord's feet; and this penitents are most found to do for remission of their sins. He who devotes himself to chastity, and continues in fastings and prayers, and other things which conduce to God's glory only, this is the ointment which anoints the Lord's head, and with whose odour the whole Church is filled; this is the work meet not for penitents, but for the perfect, or the doctrine which is necessary for men; but the acknowledgment of the faith which belongs to God alone, is the ointment with which the head of Christ is anointed, with which we are buried together with Christ by baptism into death. (Rom. 6:4.)
Hilary of Poitiers (as quoted by Aquinas, AD 1274)AD 367
Catena Aurea by Aquinas
In this woman is prefigured the people of the Gentiles, who gave glory to God in Christ's passion; for she anointed His head, but the head of Christ is God, and ointment is the fruit of good works. But the disciples, anxious for the salvation of Israel, say that this ought to have been sold for the use of the poor; designating by a prophetic instinct the Jews, who lacked faith, by the name of the poor. The Lord answers that there is abundant time in which they may show their care for the poor, but that salvation cannot be extended to the Gentiles but by obedience to His command, if, that is, by the pouring out of this woman's ointment they are buried together with Him, because regeneration can only be given to those who are dead in the profession of baptism. And this her work shall be told wherever this Gospel is preached, because when Israel draws back, the glory of the Gospel is preached by the belief of the Gentiles.
Hilary of PoitiersAD 367
Commentary on Matthew 29.2
This woman prefigures the Gentile people, who gave glory to God in the suffering of Christ. She thoroughly anointed his head. Recall that Christ’s head is God. Ointment represents the fruit of good works. And special thanks are due to the female gender for the care of the body. So then, he transferred all care of his body and all affection for his precious soul to the honor and praise of God. But the disciples, keen on saving Israel, become quickly upset as usual: “This ought to have been sold to help the poor.” But the ointment the woman carried was not for sale.
Ambrose of Milan (as quoted by Aquinas, AD 1274)AD 397
Catena Aurea by Aquinas
(in Luc. 7, 37.) It is possible therefore that they were different persons, and so all appearance of contradiction between the Evangelists is removed. Or it is possible that it was the same woman at two different times and two different stages of desert; first while yet a sinner, afterwards more advanced.
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
(Hom. lxxx.) And in this way it may be the same in the three Evangelists, Matthew, Mark, and Luke. And not without good reason does the Evangelist mention Simon's leprosy, to show what gave this woman confidence to come to Christ. The leprosy was an unclean disease; when then she saw that Jesus had healed the man with whom He now lodged, she trusted that He could also cleanse the uncleanness of her soul; and so whereas other women came to Christ to be healed in their bodies, she came only for the honour and the healing of her soul, having nothing diseased in her body; and for this she is worthy our highest admiration. But she in John is a different woman, the wonderful sister of Lazarus.

The disciples had heard their Master say, I will have mercy, and not sacrifice, (Matt. 9:13.) wherefore they thought among themselves, If He accepts not burnt-offerings, much less will He the application of such ointment as this.

The disciples then thought thus, but Jesus, who saw the thoughts of the woman, suffered it. For her piety was great, and her ardour unspeakable, wherefore He condescended to suffer her to pour the ointment on His head. As the Father admitted the smoke and odour of the slain victim, so also Christ admitted this votive anointing of His head, though the disciples, who saw not her heart, murmured.

And He says not merely, She hath wrought a good work, but says first, Why trouble ye the woman? to teach us that every good act that is wrought by any, even though it lack somewhat of exact propriety, yet we ought to receive, cherish, and cultivate it, and not to require strict correctness in a beginner. If He had been asked before this was done by the woman, He would not have directed its doing; but when it was done, the rebuke of the disciples had no longer any place, and He Himself to guard the woman from importunate attacks speaks these things for her comfort.

That this mention of His death and burial might not cause her to despond, He comforts her by what follows, Verily I say unto you, Wheresoever &c.

Behold the accomplishment of this saying; to whatsoever part of the world you go, you will find this woman famous, and this has been wrought by the power of Him who spake this word. How many victories of kings and captains have passed into oblivion; how many who built cities and enslaved many nations are now known neither by report nor by name; but the deed of this woman pouring forth ointment in the house of a leper in the presence of twelve men, this resoimds throughout the world, and though so much time has elapsed, the memory of that which was done is not effaced. But why promised He no spiritual gift to this woman, but everlasting remembrance only? Because this He did promise made her confident of receiving the other also; whereas she wrought a good work, it is clear that she shall receive an adequate reward.
John ChrysostomAD 407
Homily on the Gospel of Matthew 80
This woman seems indeed to be one and the same with all the evangelists, yet she is not so; but though with the three she doth seem to me to be one and the same, yet not so with John, but another person, one much to be admired, the sister of Lazarus.

But not without purpose did the evangelist mention the leprosy of Simon, but in order that He might show whence the woman took confidence, and came unto Him. For inasmuch as the leprosy seemed a most unclean disease, and to be abhorred, and yet she saw Jesus had both healed the man (for else He would not have chosen to have tarried with a leper), and had gone into his house; she grew confident, that He would also easily wipe off the uncleanness of her soul. And not for nought doth He name the city also, Bethany, but that thou mightest learn, that of His own will He cometh to His passion. For He who before this was fleeing through the midst of them; then, at the time when their envy was most kindled, comes near within about fifteen furlongs; so completely was His former withdrawing Himself a part of a dispensation.

The woman therefore having seen Him, and having taken confidence from thence came unto Him. For if she that had the issue of blood, although conscious to herself of nothing like this, yet because of that natural seeming uncleanness, approached Him trembling and in fear; much more was it likely this woman should be slow, and shrink back because of her evil conscience. Wherefore also it is after many women, the Samaritan, the Canaanite, her that had the issue of blood, and other besides, that she cometh unto Him, being conscious to herself of much impurity; and then not publicly but in a house. And whereas all the others were coming unto Him for the healing of the body alone, she came unto Him by way of honor only, and for the amendment of the soul. For neither was she at all afflicted in body, so that for this most especially one might marvel at her.

And not as to a mere man did she come unto Him; for then she would not have wiped His feet with her hair, but as to one greater than man can be. Therefore that which is the most honorable member of the whole body, this she laid at Christ's feet, even her own head.

And whence had they this thought? They used to hear their Master saying, "I will have mercy, and not sacrifice," and blaming the Jews, because they omitted the weightier matters, judgment, and mercy, and faith, and discoursing much on the mount concerning almsgiving, and from these things they inferred with themselves, and reasoned, that if He accepts not whole burnt offerings, neither the ancient worship, much more will He not accept the anointing of oil.

But though they thus thought, He knowing her intention suffers her. For indeed great was her reverence, and unspeakable her zeal; wherefore of this exceeding condescension, He permitted the oil to be poured even on His head.

For if He refused not to become man, and to be borne in the womb, and to be fed at the breast, why marvellest thou, if He doth not utterly reject this? For like as the Father suffered a savor of meat, and smoke, even so did He the harlot, accepting, as I have already said, her intention. For Jacob too anointed a pillar to God, and oil was offered in the sacrifices, and the priests were anointed with ointment.

But the disciples not knowing her purpose found fault unseasonably, and by the things they laid to her charge, they show the woman's munificence. For saying, that it might have been sold for three hundred pence, they showed how much this woman had spent on the ointment, and how great generosity she had manifested. Wherefore He also rebuked them, saying, "Why trouble ye the woman?" And He adds a reason, as it was His will again to put them in mind of His passion, "For she did it," He said, "for my burial." And another reason. "For ye have the poor always with you, but me ye have not always;" and, "Wheresoever the gospel shall be preached, that shall be told also which this woman hath done."

Seest thou how again He declares beforehand the going forth unto the Gentiles, in this way also consoling them for His death, if after the cross His power was so to shine forth, that the Gospel should be spread abroad in every part of the earth.

Who then is so wretched as to set his face against so much truth? For lo! what He said is come to pass, and to whatever part of the earth thou mayest go, thou wilt see her celebrated.

And yet neither was the person that did it distinguished, nor had what was done many witnesses, neither was it in a theatre, but in a house, that it took place, the disciples only being present.

Who then proclaimed it, and caused it to be spread abroad? It was the power of Him who is speaking these words. And while of countless kings and generals the noble exploits even of those whose memorials remain have sunk into silence; and having overthrown cities, and encompassed them with walls, and set up trophies, and enslaved many nations, they are not known so much as by hearsay, nor by name, though they have both set up statues, and established laws; yet that a woman who was a harlot poured out oil in the house of some leper, in the presence of ten men, this all men celebrate throughout the world; and so great a time has passed, and yet the memory of that which was done hath not faded away, but alike Persians and Indians, Scythians and Thracians, and Sarmatians, and the race of the Moors, and they that dwell in the British Islands, spread abroad that which was done secretly in a house by a woman that had been a harlot.

Great is the loving-kindness of the Lord. He endureth an harlot, an harlot kissing his feet, and moistening them with oil, and wiping them with her hair, and He receives her, and reproves them that blame her. For neither was it right that for so much zeal the woman should be driven to despair.

But mark thou this too, how far they were now raised up above the world, and forward in almsgiving. And why was it He did not merely say, "She hath wrought a good work," but before this, "Why trouble ye the woman?" That they might learn not at the beginning to require too high principles of the weaker sort. Therefore neither doth He examine the act merely itself by itself, but taking into account the person of the woman. And indeed if He had been making a law, He would not have brought in the woman, but that thou mightest learn that for her sake these things were said, that they might not mar her budding faith, but rather cherish it, therefore He saith it, teaching us whatever good thing may be done by any man, though it be not quite perfect, to receive it, and encourage it, and advance it, and not to seek all perfection at the beginning. For, that at least He Himself would rather have desired this, is manifest from the fact, that He required a bag to be borne, who had not where to lay His head. But then the time demanded not this, that He should correct the deed, but that He should accept it only. For even as, if any one asked Him, without the woman's having done it, He would not have approved this; so, after she had done it, He looks to one thing only, that she be not driven to perplexity by the reproof of the disciples, but that she should go from His care, having been made more cheerful and better. For indeed after the oil had been poured out, their rebuke had no seasonableness.

Do thou then likewise, if thou shouldest see any one provide sacred vessels and offer them, and loving to labor upon any other ornament of the church, about its walls or floor; do not command what has been made to be sold, or overthrown, lest thou spoil his zeal. But if, before he had provided them, he were to tell thee of it, command it to be given to the poor; forasmuch as He also did this not to spoil the spirit of the woman, and as many things as He says, He speaks for her comfort.

Then because He had said, "She hath done it for my burial;" that He might not seem to perplex the woman, by making mention of such a thing as this, His burial and death, I mean; see how by that which follows He recovers her, saying, "What she hath done shall be spoken of in the whole world."

And this was at once consolation to His disciples, and comfort and praise to her. For all men, He saith, shall celebrate her hereafter; and now too hath she announced beforehand my passion, by bringing unto me what was needed for a funeral, let not therefore any man reprove her. For I am so far from condemning her as having done amiss, or from blaming her as having not acted rightly, that I will not suffer what hath been done to lie hid, but the world shall know that which has been done in a house, and in secret. For in truth the deed came of a reverential mind, and fervent faith, and a contrite soul.

And wherefore did He promise the woman nothing spiritual; but the perpetual memory? From this He is causing her to feel a confidence about the other things also. For if she hath wrought a good work, it is quite evident she shall receive a due reward.
JeromeAD 420
COMMENTARY ON MATTHEW 4.26.6
About to suffer for the whole world and to redeem all nations by his blood, Jesus tarries in Bethany at the home of obedience. It was once the house of Simon the leper—but he was no longer a leper. After he had been cured by the Savior he was still known by his original name, that the power of the healer might appear. In fact, one of the apostles listed with his original occupation and vice is Matthew the publican, though he certainly ceased to be a publican. There are those who want the house of Simon the leper to be known as that part of the people who believed in the Lord and were cured by him. Simon himself, moreover, is termed the obedient one. His name can be interpreted also as “the clean one” in whose house the church was healed.
Jerome (as quoted by Aquinas, AD 1274)AD 420
Catena Aurea by Aquinas
Not that he was a leper yet, but having been so, and having been healed by the Saviour, he retained the appellation to show forth the power of Him who healed him.

Another Evangelist (John 12:3.) instead of 'alabastrum' has 'nardum pisticam,' that is, genuine, unadulterated.

For let no one think that she who anointed His head and she who anointed His feet were one and the same; for the latter washed His feet with her tears, and wiped them with her hair, and is plainly said to have been a harlot. But of this woman nothing of this kind is recorded, and indeed a harlot could not have at once been made deserving of the Lord's head.

I know that some raise a cavil here, because John says that Judas alone was grieved because he had the bag, and was a thief from the beginning; but Matthew, that all the disciples were sorrowful. These know not the figure syllepsis, by which one name is put for many, and many for one; as Paul in the Epistle to the Hebrews says, They were sawn asunder, when it is thought that one only, Esaias namely, was so. (Heb. 11:37.)

Here a question arises how the Lord should have said elsewhere to His disciples, Lo, I am with you always, even to the end of the world; but here, Me ye shall not have always. (Matt. 28:20.) I suppose that in this place He speaks of His bodily presence, which shall not be with them after the resurrection in daily intercourse and friendship, as it is now.

Note His knowledge of things to come, how though about to suffer death within two days, He knows that His Gospel will be preached throughout the whole world.

Mystically; The Lord, about to suffer for the whole world, sojourns in Bethany, in the house of obedience, which once was that of Simon the leper. Simon also is interpreted 'obedient,' or, according to another interpretation, 'the world,' in whose house the Church is healed.
JeromeAD 420
Commentary on Matthew
(Verse 6) But when Jesus was in Bethany, in the house of Simon the leper. About to suffer for the whole world and redeem all nations with his blood, he stayed in Bethany, the house of obedience, which was once Simon the leper's. Not that he remained a leper at that time, but he who was formerly a leper was cleansed by the Savior, with his former name remaining, so that the power of the healer may be apparent. For in the list of apostles, with his former vice and occupation, Matthew is called a tax collector, who had certainly ceased to be a tax collector. A certain Simon, a leper's house, they want it to be understood as a part of the people, which has believed in the Lord, and has been cured by him. Simon himself is also said to be obedient, who can be interpreted in another sense as the world, in whose house the Church is healed.
Augustine of Hippo (as quoted by Aquinas, AD 1274)AD 430
Catena Aurea by Aquinas
(de Cons. Ev. ii, 79.) Though the action described in Luke is the same as that described here, and the name of him with whom the Lord supped is the same, for Luke also names Simon; yet because it is not contrary to either nature or custom for two men to bear the same name, it is more probable that this was another Simon, not the leper, in whose house in Bethany these things were done. I would only suppose that the woman who on that occasion came near to Jesus' feet, and this woman, were not two different persons, but that the same Mary did this twice. The first time is that narrated by Luke; for John mentions it in praise of Mary before Christ's coming to Bethany, It was that Mary who anointed the Lord with ointment, and wiped his feet with her hair, whose brother Lazarus was sick. (John 11:2.) Mary therefore had done this before. That she did afterwards in Bethany is distinct from Luke's account, but is the same event that is recorded by all three, John, Matthew, and Mark. That Matthew and Mark say it was the Lord's head that she anointed, and John His feet, is reconciled by supposing that she anointed both. Against this one might raise a cavil from what Mark says, that she anointed His head by breaking the box over it, so that there could be none of the ointment left with which to anoint His feet also. Let such caviller understand, that His feet were first anointed before the box was broken, and there remained in it, yet whole, enough wherewith to anoint the head by breaking the box and shedding the contents.

(de Doctr. Christ. iii, 12.) But let not any suppose that the Lord's feet were by this woman bathed in ointment after the manner which the luxurious and debauched use. In all things of this nature, it is not the thing itself, but the mind of him who uses it, that is in fault. Whoso uses things after such sort as to pass the bounds observed by good men with whom he lives, either has some meaning in what he does, or is vicious. What then is vice in others, in a divine or prophetic person is a sign of some great thing. The good odour is the good report which one has gained by the works of a good life, and in following Christ's footsteps sheds a most precious odour on His feet.

(de Cons. Ev. ii. 78.) Still there may seem to be some discrepancy between the narrative of Matthew and Mark, who say, that after two days is the feast of the Passover, and then bring Jesus to Bethany; and that of John, who, relating this history of the ointment, says Six days before the Passover. They who urge this do not understand that the events in Bethany are in Matthew and Mark inserted out of their place, a little later than the time of their occurrence. Neither of them, it is to be observed, introduce their account with 'afterwards.'

(de Cons. Ev. ii. 79.) We may however understand that the other disciples thought or said the same, or that they assented to what Judas said, and thus Matthew and Mark have described their common consent. But Judas said it because he was a thief, the others out of their care for the poor; and John desired to mention it only in the case of him whose thievish propensity he thought ought to be recorded.
Leo the Great (as quoted by Aquinas, AD 1274)AD 461
Catena Aurea by Aquinas
(Serm. 58, 1.) We recognise here a providential arrangement whereby the chief men of the Jews, who had often sought occasion of effecting their cruel purposes against Christ, could never yet succeed till the days of the paschal celebration. For it behoved that the things which had long been promised in symbol and mystery should be accomplished in manifest reality, that the typical lamb should be displaced by the true, and one sacrifice embrace the whole catalogue of the varied victims. That shadows should give way to substance, and copies to the presence of the original; victim is commuted for victim, blood is abolished by blood, and the festival of the Law is at once fulfilled and changed.
Remigius of Rheims (as quoted by Aquinas, AD 1274)AD 533
Catena Aurea by Aquinas
He clearly shows that the Apostles had uttered something harsh against her, when He says, Why trouble ye the woman? And beautifully He adds, She hath wrought a good work in me; as much as to say, It is not a waste of ointment, as ye say, but a good work, that is, a service of piety and devotion.

For the poor ye have ever with you. The Lord shows in these words as of set purpose, that they were not to be blamed who ministered of their substance to Him while He dwelt in a mortal body; forasmuch as the poor were ever in the Church, to whom the believers might do good whensoever they would, but He would abide in the body with them but a very short time; whence it follows, But me ye shall not have always.

Or, it is to be explained by supposing this spoken to Judas only; and He said not, Ye have not, but Ye shall not have, because this was spoken in the person of Judas to all his followers. And He says, Not always, though they have it at no time, because the wicked seem to have Christ in this present world, while they mix among His members and approach His table, but they shall not always so have Him when He shall say to His elect, Come, ye blessed of my Father. (Matt. 25:34.) It was the custom among this people to embalm the bodies of (Matt. 25:34.) the dead with divers spices, to the end that they might be kept from corruption as long as possible. And as this woman was desirous of embalming the Lord's dead Body, and would not be able because she would be anticipated by His resurrection, it was therefore arranged by Divine Providence that she should anoint the Lord's living Body. This then is what He says, In that she hath poured, that is, By anointing My living Body she shows forth My death and burial.
Gregory the Dialogist (as quoted by Aquinas, AD 1274)AD 604
Catena Aurea by Aquinas
(Hom. in Ev. xxxiii. 1.) Or, we may think that this is the same woman whom Luke calls a sinner, and John names Mary.
Rabanus Maurus (as quoted by Aquinas, AD 1274)AD 856
Catena Aurea by Aquinas
Alabaster is a kind of marble, white but marked with veins of different colours, which was in use for vessels to hold ointment, because it was said to preserve it from corruption.

From the Greek πίστις, faith, whence 'pisticus,' faithful. For this ointment was pure, unadulterated.

That is, To whatsoever place throughout the whole world the Church shall be propagated, there this also that she hath done shall be told. That also that is added signifies, that as Judas by his reproof of her has earned evil character of treachery, so has she also earned the glory of pious devotedness.
Glossa Ordinaria (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(non occ.) Having set before us the counsels of the chief of the Jews concerning the death of Christ, the Evangelist would proceed to follow out their execution, and to relate the bargain of Judas with the Jews to deliver Him up, but he first shows the cause of this betrayal. He was grieved that the ointment which the woman poured upon Christ's head had not been sold that he might have carried off something out of the price it brought, and to make up this loss he was willing to betray his Master. And therefore he proceeds, Now when Jesus was in Bethany, in the house of Simon the leper.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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