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“Jesus Prays for His Immediate Disciples”· John 17:6–19
Translation
King James Version
Sanctify them through thy truth: thy word is truth.
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KJV (with Strong's)
Sanctify G37 them G846 through G1722 thy G4675 truth G225: thy G4674 word G3056 is G2076 truth G225.
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Complete Jewish Bible
Set them apart for holiness by means of the truth — your word is truth.
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Berean Standard Bible
Sanctify them by the truth; Your word is truth.
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American Standard Version
Sanctify them in the truth: thy word is truth.
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World English Bible Messianic
Sanctify them in your truth. Your word is truth.
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Geneva Bible (1599)
Sanctifie them with thy trueth: thy word is trueth.
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Young's Literal Translation
sanctify them in Thy truth, Thy word is truth;
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Study This Verse

Summary

In this pivotal verse from Jesus' High Priestly Prayer, offered just hours before His crucifixion, Jesus intercedes for His disciples, and by extension all future believers, that they might be set apart and made holy through God's truth. He profoundly declares that God's very Word is the embodiment and essence of this truth, establishing it as the divine instrument for the sanctification of His followers.

Context

Literary Context

This verse is nestled within the profound and intimate discourse known as Jesus' High Priestly Prayer, recorded in John 17. Following His extensive farewell discourses to His disciples in John 13-16 and just prior to His arrest in Gethsemane, Jesus turns His focus heavenward. The prayer unfolds in three distinct movements: Jesus prays for Himself (John 17:1-5), then for His immediate disciples (John 17:6-19), and finally for all future believers who would come to faith through their witness (John 17:20-26). Within the section concerning His disciples, Jesus acknowledges their unique position—they are "in the world" but "not of the world" (John 17:14-16). His prayer for their sanctification by truth is a direct response to the spiritual dangers and pressures they would face in a hostile world, emphasizing their need for divine preservation and consecration for their mission.

Historical & Cultural Context

The concept of "truth" (ἀλήθεια, alḗtheia) held significant philosophical and religious weight in both Jewish and Greco-Roman thought. For the Jewish people, truth was intrinsically linked to God's revelation, His covenant faithfulness, and the integrity of His Word (Torah). It was not merely an abstract concept but a living reality embodied in God's character and His commands, serving as the foundation for a righteous life. In contrast, the Greco-Roman world, particularly among philosophical schools, often debated the nature of truth, with some embracing objective truth and others leaning towards skepticism or subjective interpretations. Jesus' bold declaration, "thy word is truth," directly challenges any relativistic or human-centered understanding of truth, grounding it firmly in the divine revelation of God the Father. The idea of "sanctification" (ἁγιάζω, hagiázō) also resonates with Old Testament practices of setting apart people, objects, or places for sacred use, making them holy and distinct for God's purposes, often through ritual purification and adherence to divine law.

Key Themes

This verse powerfully contributes to several overarching themes within John's Gospel and biblical theology. Firstly, Sanctification is a central theme, highlighting the divine process by which believers are set apart from sin and the world, consecrated to God, and progressively transformed into Christlikeness. This sanctification is not self-achieved but is a work of God, initiated and sustained by Him. Secondly, the Nature of Truth is profoundly defined. Jesus declares that God's Word is not merely a truth but is truth itself, establishing it as the ultimate, objective, and authoritative standard for reality, morality, and spiritual understanding. This contrasts sharply with human opinions or worldly philosophies. Thirdly, the Power and Authority of God's Word is underscored. The Word is presented not as inert information but as a living, active, and transformative force, the very instrument through which God accomplishes His sanctifying work in believers. This aligns with the Gospel's opening declaration of Jesus as the Logos, the Word made flesh, who brings light and truth into the world. The emphasis on truth also connects to Jesus' earlier teaching that His disciples would know the truth, and the truth would set them free.

Exposition and Analysis

Key Word Analysis

Sanctify hagiázō' G37

From ἅγιος (hagios), meaning "holy," this verb signifies "to make holy," "to purify," or "to consecrate." It carries the dual sense of being set apart from common use and dedicated exclusively to God's service, and also being purified morally and spiritually. In this context, it refers to God's divine act of setting believers apart for Himself and purifying them through His truth.

truth alḗtheia' G225

Derived from ἀληθής (alēthēs), meaning "true," this noun denotes "truth," "reality," or "veracity." It implies freedom from concealment, falsehood, or deception. Here, it refers to the absolute, objective, and reliable nature of God's revelation, which stands in stark contrast to human error or illusion.

word lógos' G3056

From λέγω (legō), "to say," this comprehensive term can mean "something said," "discourse," "reason," or "computation." Crucially, in John's Gospel, especially with the definite article ("the Word"), it specifically refers to "the Divine Expression," which is Christ Himself. In this verse, it refers to God's revealed communication, encompassing His commands, promises, and ultimately, His Son.

Verse Breakdown

"Sanctify them through thy truth:"

Jesus prays to the Father, asking Him to perform a divine work of sanctification upon His disciples. This sanctification is not a human endeavor but a divine act, achieved "through" (Greek: en, denoting instrumentality or means) the Father's truth. This implies that God's truth is the active agent or medium by which believers are set apart for holy living and purified from sin. It's a prayer for both positional holiness (being declared holy by God) and progressive holiness (growing in practical righteousness).

"thy word is truth."

This is a profound declarative statement that defines the nature and source of the truth Jesus has just mentioned. The "thy word" refers to the Father's revealed communication, encompassing all that God has spoken and revealed, particularly through the Scriptures. By stating that this "word is truth," Jesus asserts the absolute, inherent veracity and reliability of God's revelation. It is not merely a collection of true statements, but its very essence is truth itself, making it the ultimate standard for all reality and the foundation for genuine sanctification.

Literary Devices

The verse employs several significant literary devices. Repetition of the word "truth" (ἀλήθεια, alḗtheia) at the beginning and end of the statement ("Sanctify them through thy truth: thy word is truth") serves to emphasize its paramount importance and to create a strong, memorable declaration. This repetition also forms a subtle chiasm (A-B-B'-A' structure, where "truth" is A and "thy word" is B), drawing attention to the central identity of "thy word" with "truth." Furthermore, the statement "thy word is truth" functions as a powerful declarative statement, asserting an absolute theological reality rather than merely a suggestion or opinion. It also contains an implicit metaphor, where "word" is equated with "truth," highlighting the living and active nature of God's revelation as the very substance of reality and holiness.

Theological and Thematic Connections

John 17:17 serves as a cornerstone for understanding the nature of Christian holiness and the indispensable role of divine revelation. It teaches us that true sanctification is not a self-improvement project or an outcome of human effort, but a gracious work of God the Father, mediated through His objective and authoritative Word. This divine truth, embodied in Scripture, actively purifies, transforms, and sets believers apart for God's purposes, providing the standard for righteousness and the power for living it out. It underscores the biblical conviction that God's Word is living and active, capable of discerning the thoughts and intentions of the heart, and equipping believers for every good work, making them complete in Christ.

Reflection and Application

John 17:17 calls believers to a profound engagement with God's Word as the primary means of spiritual growth and transformation. In a world saturated with subjective truths and fleeting opinions, Jesus' declaration provides an unshakeable anchor: God's Word is the ultimate, unchanging truth. Therefore, to be sanctified—to be set apart for God and progressively made holy—requires intentional and consistent immersion in Scripture. This means not merely reading it, but meditating on it, allowing its truth to penetrate our minds and hearts, shaping our worldview, correcting our errors, and guiding our paths. It invites us to align our lives with God's revealed will, trusting that as we submit to His Word, He will purify us and equip us to live distinct, holy lives that bear witness to His character in the world. Our pursuit of holiness is thus a pursuit of God's truth, found in His Word.

Questions for Reflection

  1. How does my daily engagement with God's Word reflect my belief that it is the very truth by which God sanctifies me?
  2. In what specific areas of my life do I need God's truth to purify and set me apart for His purposes?
  3. How does Jesus' prayer for our sanctification inform my understanding of spiritual growth as a divine work rather than solely a human effort?
  4. Considering that "thy word is truth," how does this impact my discernment of information and ideas presented by the world?

FAQ

What does "sanctify" mean in this context?

In John 17:17, "sanctify" (Greek: hagiázō) means to set apart, consecrate, or make holy. It encompasses both a positional holiness, where believers are declared holy by God through Christ, and a progressive holiness, where they are continually purified and transformed by God's truth to live lives increasingly aligned with His character and purposes. It is a divine act of God, separating believers from the world and dedicating them to Himself.

Why does Jesus emphasize "thy word is truth" so strongly?

Jesus emphasizes "thy word is truth" to establish the absolute authority and reliability of God's revealed communication as the foundation for all true understanding and spiritual transformation. In a world filled with shifting philosophies and subjective interpretations, Jesus unequivocally declares that God's Word is the objective standard of reality. This divine Word, which ultimately points to and is embodied by Jesus Himself as the Word made flesh, is the means by which God purifies and sets His people apart. It highlights that sanctification is not based on human wisdom or effort, but on divine revelation.

How does God's Word sanctify believers in a practical sense?

God's Word sanctifies believers practically by revealing God's character, His will, and His standards for righteousness. As believers engage with Scripture, it illuminates sin (Psalm 119:105), corrects wrong thinking, instructs in right living, and equips for good works (2 Timothy 3:16-17). It renews the mind, transforms desires, and empowers obedience through the work of the Holy Spirit. By immersing ourselves in God's truth, we are progressively conformed to the image of Christ, becoming more holy and set apart for His glory.

Christ-Centered Fulfillment

John 17:17 finds its ultimate Christ-centered fulfillment in Jesus Himself, who is the embodiment of God's truth and the living Word. As John 1:1 declares, "In the beginning was the Word, and the Word was with God, and the Word was God." This divine Word, the Logos, became flesh in Jesus Christ (John 1:14), making Him the full and perfect revelation of the Father's truth. Therefore, when Jesus prays, "Sanctify them through thy truth: thy word is truth," He is not only referring to the written Scriptures but also to Himself as the living Truth (John 14:6). Our sanctification is inextricably linked to our union with Christ, for He is our holiness (1 Corinthians 1:30). Through His atoning sacrifice, He has already set us apart positionally, and through His indwelling Spirit, who is the Spirit of truth (John 16:13), He continually applies the truth of God's Word to our lives, progressively transforming us into His likeness. Thus, our sanctification by truth is ultimately our sanctification in and through Jesus Christ, the Truth incarnate.

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Public-domain commentary

Matthew Henry

From his Commentary on the Whole Bible. Henry comments on passages, not single verses — this entry covers John 17:17–19. His four-level outline is real structure in the source text, so it is rendered as structure.

1662–1714 · 3 verses
Passage under commentJohn 17:17–19
I. II. Main points1. 2. Sub-points(1.) (2.) Details[1.] [2.] Fine details

The next thing he prayed for for them was that they might be sanctified; not only kept from evil, but made good.

I.Here is the petition (Joh 17:17):

Sanctify them through thy truth, through thy word, for thy word is truth; it is true - it is truth itself. He desires they may be sanctified,

1.As Christians. Father, make them holy, and this will be their preservation, Th1 5:23. Observe here,

(1.)The grace desired - sanctification. The disciples were sanctified, for they were not of the world; yet he prays, Father sanctify them, that is, [1.] "Confirm the work of sanctification in them, strengthen their faith, inflame their good affections, rivet their good resolutions." [2.] "Carry on that good work in them, and continue it; let the light shine more and more." [3.] "Complete it, crown it with the perfection of holiness; sanctify them throughout and to the end." Note, First, It is the prayer of Christ for all that are his that they may be sanctified; because he cannot for shame own them as his, either here or hereafter, either employ them in his work or present them to his Father, if they be not sanctified. Secondly, Those that through grace are sanctified have need to be sanctified more and more. Even disciples must pray for sanctifying grace; for, if he that was the author of the good work be not the finisher of it, we are undone. Not to go forward is to go backward; he that is holy must be holy still, more holy still, pressing forward, soaring upward, as those that have not attained. Thirdly, It is God that sanctifies as well as God that justified, Co2 5:5. Fourthly, It is an encouragement to us, in our prayers for sanctifying grace, that it is what Christ intercedes for for us.

(2.)The means of conferring this grace - through thy truth, thy word is truth. Not that the Holy One of Israel is hereby limited to means, but in the counsel of peace among other things it was settled and agreed,

[1.]That all needful truth should be comprised and summed up in the word of God. Divine revelation, as it now stands in the written word, is not only pure truth without mixture, but entire truth without deficiency.

[2.]That this word of truth should be the outward and ordinary means of our sanctification; not of itself, for then it would always sanctify, but as the instrument which the Spirit commonly uses in beginning and carrying on that good work; it is the seed of the new birth (Pe1 1:23), and the food of the new life, Pe1 2:1-2.

2.As ministers. "Sanctify them, set them apart for thyself and service; let their call to the apostleship be ratified in heaven." Prophets were said to be sanctified, Jer 1:5. Priests and Levites were so. Sanctify them; that is, (1.) "Qualify them for the office, with Christian graces and ministerial gifts, to make them able ministers of the New Testament." (2.) "Separate them to the office, Rom 1:1. I have called them, they have consented; Father, say Amen to it." (3.) "Own them in the office; let thy hand go along with them; sanctify them by or in thy truth, as truth is opposed to figure and shadow; sanctify them really, not ritually and ceremonially, as the Levitical priests were, by anointing and sacrifice. Sanctify them to thy truth, the word of thy truth, to be the preachers of thy truth to the world; as the priests were sanctified to serve at the altar, so let them be to preach the gospel." Co1 9:13, Co1 9:14. Note, [1.] Jesus Christ intercedes for his ministers with a particular concern, and recommends to his Father's grace those stars he carries in his right hand. [2.] The great thing to be asked of God for gospel ministers is that they may be sanctified, effectually separated from the world, entirely devoted to God, and experimentally acquainted with the influence of that word upon their own hearts which they preach to others. Let them have the Urim and Thummim, light and integrity.

II.We have here two pleas or arguments to enforce the petition for the disciples' sanctification: -

1.The mission they had from him (Joh 17:18): "As thou hast sent me into the world, to be thine ambassador to the children of men, so now that I am recalled have I sent them into the world, as my delegates." Now here,

(1.)Christ speaks with great assurance of his own mission: Thou hast sent me into the world. The great author of the Christian religion had his commission and instructions from him who is the origin and object of all religion. He was sent of God to say what he said, and do what he did, and be what he is to those that believe on him; which was his comfort in his undertaking, and may be ours abundantly in our dependence upon him; his record was on high, for thence his mission was.

(2.)He speaks with great satisfaction of the commission he had given his disciples "So have I sent them on the same errand, and to carry on the same design;" to preach the same doctrine that he preached, and to confirm it with the same proofs, with a charge likewise to commit to other faithful men that which was committed to them. He gave them their commission (Joh 20:21) with a reference to his own, and it magnifies their office that it comes from Christ, and that there is some affinity between the commission given to the ministers of reconciliation and that given to the Mediator; he is called an apostle (Heb 3:1), a minister (Rom 15:8), a messenger, Mal 3:1. Only they are sent as servants, he as a Son. Now this comes in here as a reason,

[1.]Why Christ was concerned so much for them, and laid their case so near his heart; because he had himself put them into a difficult office, which required great abilities for the due discharge of it. Note, Whom Christ sends he will stand by, and interest himself in those that are employed for him; what he calls us out to he will fit us out for, and bear us up in.

[2.]Why he committed them to his Father; because he was concerned in their cause, their mission being in prosecution of his, and as it were an assignment out of it. Christ received gifts for men (Psa 68:18), and then gave them to men (Eph 4:8), and therefore prays aid of his Father to warrant and uphold those gifts, and confirm his grant of them. The Father sanctified him when he sent him into the world, Joh 10:36. Now, they being sent as he was, let them also be sanctified.

2.The merit he had for them is another thing here pleaded (Joh 17:19): For their sakes I sanctify myself. Here is,

(1.)Christ's designation of himself to the work and office of Mediator: I sanctified myself. He entirely devoted himself to the undertaking, and all the parts of it, especially that which he was now going about - the offering up of himself without spot unto God, by the eternal Spirit. He, as the priest and altar, sanctified himself as the sacrifice. When he said, Father, glorify thy name - Father, thy will be done - Father, I commit my spirit into thy hands, he paid down the satisfaction he had engaged to make, and so sanctified himself. This he pleads with his Father, for his intercession is made in the virtue of his satisfaction; by his own blood he entered into the holy place (Heb 9:12), as the high priest, on the day of atonement, sprinkled the blood of the sacrifice at the same time that he burnt incense within the veil, Lev 16:12, Lev 16:14.

(2.)Christ's design of kindness to his disciples herein; it is for their sakes, that they may be sanctified, that is, that they may be martyrs; so some. "I sacrifice myself, that they may be sacrificed to the glory of God and the church's good." Paul speaks of his being offered, Phi 2:17; Ti2 4:6. Whatever there is in the death of the saints that is precious in the sight of the Lord, it is owing to the death of the Lord Jesus. But I rather take it more generally, that they may be saints and ministers, duly qualified and accepted of God.

[1.]The office of the ministry is the purchase of Christ's blood, and one of the blessed fruits of his satisfaction, and owes its virtue and value to Christ's merit. The priests under the law were consecrated with the blood of bulls and goats, but gospel ministers with the blood of Jesus.

[2.]The real holiness of all good Christians is the fruit of Christ's death, by which the gift of the Holy Ghost was purchased; he gave himself for his church, to sanctify it, Eph 5:25, Eph 5:26. And he that designed the end designed also the means, that they might be sanctified by the truth, the truth which Christ came into the world to bear witness to and died to confirm. The word of truth receives its sanctifying virtue and power from the death of Christ. Some read it, that they may be sanctified in truth, that is, truly; for as God must be served, so, in order to this, we must be sanctified, in the spirit, and in truth. And this Christ has prayed for, for all that are his; for this is his will, even their sanctification, which encourages them to pray for it,

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Historical interpretation

Historical Reception

9 surviving comments on this verse. Each one is dated, so this reads as a timeline rather than a list.

9 quotes · AD 373–444
Post-Nicene
400

Select a marker to jump to its quote. Markers stagger vertically where authors wrote within a few decades of each other.

We are made sons through Christ by adoption and grace, partaking of his Spirit. For “as many as received him,” he says, “to them he gave power to become children of God, even to them that believe on his name.” And therefore, he is also the Truth, saying, “I am the Truth,” and in his address to his Father, he said, “Sanctify them through your Truth, your Word is Truth.” We, by imitation [of this truth], become virtuous and sons. Therefore, he did not say “that they may be one as we are” so that we might become such as he is, but that as he, being the Word, is in his own Father, we too, seeing him as our example, might become one toward each other in concord and oneness of spirit, nor be at variance as the Corinthians, but be of one mind as those five thousand in the Acts of the Apostles who were as one.
AD 395Gregory of NyssaPost-NiceneSourceON THE HOLY TRINITY
The Father, the Son and the Holy Spirit alike give sanctification, life, light, comfort, and any other similar graces. And let no one attribute the power of sanctification in a special sense to the Spirit when he hears the Savior in the Gospel saying to the Father concerning his disciples, “Father, sanctify them in your name.” So too all the other gifts are produced in those who are worthy alike by the Father, the Son and the Holy Spirit: every grace and power, guidance, life, comfort, the change to immortality, the passage to liberty, and every other boon that exists, which descends to us.
AD 407John Chrysostomas quoted by Aquinas, AD 1274Post-NiceneSourceCatena Aurea by Aquinas
(Hom. lxxxii) Or thus: Sanctify them in Thy truth; i. e. Make them holy, by the gift of the Holy Spirit, and sound doctrines: for sound doctrines give knowledge of God, and sanctify the soul. And as He is speaking of doctrines, He adds, Thy word is truth, i. e. there is in it no lie, nor any thing typical, or bodily. Again, Sanctify them in Thy truth, may mean, Separate them for the ministry of the word, and preaching.
"Sanctify them through Thy truth." "Make them holy by the gift of the Spirit, and of right doctrines." As when He saith, "Ye are clean through the word which I spake unto you," so now He saith the same thing, "Instruct them, teach them the truth." "And yet He saith that the Spirit doth this. How then doth He now ask it from the Father?" That thou mayest again learn their equality of Honor. For right doctrines asserted concerning God sanctify the soul. And if He saith that they are sanctified by the word, marvel not. And to show that He speaketh of doctrines, He addeth, "Thy word is truth." That is, "there is no falsehood in it, and all that is said in it must needs come to pass"; and again, it signifieth nothing typical or bodily. As also Paul saith concerning the Church, that He hath sanctified it by the Word. For the Word of God is wont also to cleanse. Moreover, the, "sanctify them," seems to me to signify something else, such as this, "Set them apart for the Word and for preaching."
The heirs therefore of the New Testament are sanctified in that truth which was adumbrated in the purifications of the Old Testament; and when they are sanctified in the truth, they are in other words sanctified in Christ, who said in truth "I am the way, and the truth, and the life." As also when He said, "The truth shall make you free," in explanation of His words, He added soon after, "If the Son shall make you free, ye shall be free indeed;" in order to show that what He had previously called the truth, He a minute afterwards denominates the Son. And what else did He mean by the words before us, "Sanctify them in the truth," but, Sanctify them in me?

Finally, He proceeds, and doing so fails not to suggest the same with increasing clearness: "Thy speech is truth." What else did He mean than "I am the truth"? For the Greek Gospel has logos, which is also the word that is found in the passage where it is said, "In the beginning was the Word, and the Word was with God, and the Word was God." And that Word at least we know to be the only begotten Son of God, which "was made flesh, and dwelt among us." Hence also there might have been put here as it actually has been put in certain copies "Thy Word is truth;" just as in some copies that other passage is written, "In the beginning was the speech." But in the Greek without any variation it is logos in both cases. The Father therefore sanctifies in the truth, that is, in His own Word, in His Only begotten, His own heirs and His (the Son's) co-heirs.
AD 430Augustine of Hippoas quoted by Aquinas, AD 1274Post-NiceneSourceCatena Aurea by Aquinas
(Tr. cviii) Sanctify them through Thy truth: for thus were they to be kept from the evil. But it may be asked, how it was that they were not of the world, when they were not yet sanctified in the truth? Because the sanctified have still to grow in sanctity, and this by the help of God's grace. The heirs of the New Testament are sanctified in that truth, the shadows of which were the sanctification of the Old Testament; they are sanctified in Christ, Who said above, I am the way, the truth, and the life. (c. 14:6) It follows, Thy discourse is truth. The Greek is λόγος, i. e. word. The Father then sanctified them in the truth, i. e. in His Word the Only-Begotten, them, i. e. the heirs of God, and joint-heirs with Christ.
CHAPTER X. That Christ is not holy from participation in anything different from Himself; and that the sanctification through the Spirit is not alien to His Substance.

After giving the Father here especially the name of Holy, and praying that the disciples might be kept in the truth, that is, in His Spirit (for the Spirit is the truth, as John says, as He is also the Spirit of truth, that is, of the Only-begotten Himself), He declares that He sent them into the world after the fashion of His own mission; for Jesus is the Apostle and High Priest of our confession, as Paul says, in the appropriate character of His Manhood, and by the way of His humiliation. He says, then, that the disciples, after having been once for all thereto prepared, stand wholly in need of sanctification by the Holy Father, Who implanteth in them the Holy Spirit through the Son. For in truth the disciples of the Saviour would never have become so illustrious as to be the torchbearers of the whole world, nor would they have withstood the brunt of the temptations of their enemies, nor the terrible assaults of the devil, had they not had their minds fortified by communion with the Spirit; and had they not been continually thereby enabled to accomplish a bidding unheard of before and passing mere human power; and had they not been ever led by the light of the Spirit, without effort, to a perfect knowledge of the inspired writings and the holy doctrines of the Church. Furthermore, the Saviour, being assembled together with them after His resurrection from the dead, as is recorded, and bidding them preach grace through faith throughout the whole world, charged them not to depart from Jerusalem, but to wait for the promise of the Father, which they had heard of Him as well as by the mouth of the holy prophets. For it shall come to pass in those days, saith the Lord, that I will pour out My Spirit upon all flesh. And the Saviour Himself plainly declared that His Holy Spirit would be shed forth upon them, in the words: I have yet many things to say unto you, but ye cannot bear them now. Howbeit, when He, the Spirit of Truth, is come, He shall guide you into all truth; and again: I will pray the Father, and He shall give you another Comforter. For the Spirit belongeth unto God the Father, and none the less also unto the Son Himself, not as distinct Entities, or as though He was inherent or existed in Either divisibly; but, inasmuch as the Son by Nature proceeds from the Father and is in Him (being the true Offspring of His Essence), the Spirit----Which is the Father's by Nature----is brought down to men; shed forth indeed from the Father, but through the Son Himself conveyed to the creature; not merely ministerially or in the manner of a servant, but, as I said just now, proceeding from the Substance Itself of God the Father; and shed forth on those worthy to receive Him through the Word, Which is Consubstantial with and proceeded from Him, and so proceeded as to have a self-dependent being, and ever abideth in Him, at the same time in unity, and also, as it were, with an individual existence. For we maintain that the Son has an independent existence, but still inheres in His Father, and has in Himself Him that begat Him; and that the Spirit of the Father is indeed the Spirit of the Son; and that, when the Father sends or promises to distribute the Spirit to the Saints, the Son also vouchsafes the Spirit to them as His own, because of His identity in Substance with the Father. And that the Father works in every respect through Him He has Himself very clearly pointed out to us in the words: It is expedient for you that I go away: for if I go not away the Comforter cannot come unto you; but when I depart I will send Him unto you. And again: I will pray the Father, and He shall give you another Comforter. Plainly here He promises to send us the Comforter.

Since, then, the disciples, who respect My sayings, have been sent forth on their mission in the world, even as I myself, keep them, Holy Father, in Thy truth; that is, in Thy Word, in Which, and through Which, the Spirit Which sanctifies is and proceeds. And what is the Saviour's aim in saying this? He besought the Father for that sanctification which is in and through the Spirit to be given to ourselves; and He desires that which was in us at the first age of the world, and at the beginning of creation by gift of God, to be quickened anew into life. This we say, because the Only-begotten is our Mediator, and fulfils the part of Advocate for us before our Father Which is in heaven. But that we may free our explanation from all obscurity, and make the meaning of what is said clear to our hearers, let us say a few words about the creation of the first man.

The inspired Moses said concerning him, that God took dust from the earth and formed man of it. He then goes on to tell the manner in which, after the body was perfectly joined together, life was given to it. He breathed, he says, into his nostrils the breath of life; signifying that not without sanctification by the Spirit was life given to man, nor yet was it wholly devoid or barren of the Divine Nature. For never could anything, which had so base an origin, have been seen to be created in the Image of the Most High, had it not taken and received, through the Spirit moulding it, so to speak, a fair mask, by the Will of God. For as His Spirit is a perfect Likeness of the Substance of the Only-begotten, according to the saying of Paul: For whom He foreknew, He also fore-ordained to be conformed to the Image of His Son, He maketh those in whom He abides to be conformed to the Image of the Father, that is, the Son; and thus all thoughts are uplifted through the Son to the Father, from Whom He proceeds by the Spirit. He desires, therefore, the nature of man to be renewed, and moulded anew, as it were, into its original likeness, by communion with the Spirit; in order that, putting on that pristine grace, and being shaped anew into conformity with Him, we may be found able to prevail over the sin that reigns in this world, and may simply cling to the love of God, striving with all our might after whatsoever things be good, and, lifting our minds above fleshly lusts, may keep the beauty of His Image implanted in ourselves unspoiled. For this is spiritual life, and this is the meaning of worship in the Spirit.
By these words He indicates once more, and makes clear to us, the reason why He requires to ascend to God the Father, and why so to do becomes Him, while He is still our Mediator, and High Priest, and Advocate, according to the Holy Scripture; and shows us that it is in order that, if at any time we encounter failure, or miss the straight path in thought or action, or are assailed by unexpected perils or buffeted by the tempest of the devil's malice, He may approach His Father on our behalf in His appropriate character as Mediator; and join with Him in granting good gifts to those who are worthy. For it would well become Him so to do, as He is God by Nature. Those then, He says, who have received Thy Word, O Father, through Me, show forth My Likeness in themselves and are conformed to the pattern of Thine own Son, who, like Him, pass unscathed through the ocean of the world's wickedness, and have shown themselves foreigners and strangers to the love of pleasure in this life, and every kind of vice. Therefore keep them in Thy truth, for exceeding purity is inherent in Christ. For He is truly God, and cannot be subject to sin nor endure it, but is rather the fountain of all goodness, and the beauty of holiness. For the Divine Nature, that ruleth over all, can do nothing but what is in truth suitable and belongeth thereto. And the holy disciples, I mean all who believe on Him, cannot otherwise exhibit purity unspotted by the wickedness of this world than by means of forgiveness and grace from above, which putteth away the defilement of previous offences and the accusing sins of their past lives; and, further, conferring on them the glory of a life of sanctification, though their continuance therein be not free from conflict, as Paul wisely teaches us, saying: Wherefore let him that thinketh he standeth take heed lest he fall. For our life is cast upon the deep, and we are tossed by divers storms, as the devil tempts without ceasing, and continually assails and strives to defile if he can, by the insidious inventions of malice, even those who have been already made pure. For his meat is well chosen, as the prophet says. Having then borne witness to His disciples that their life was out of the world, and that they were conformed to the likeness of His own essential purity, He proceeds to pray to His Father to keep them. It is almost as though He said: O Holy Father, if they were in the world----that is, if they lived the life that has honour in this world----if, sowing the seed of earthly and temporary pleasure in their hearts, they imprinted on themselves the foul image of the evil one, would not have attacked them with temptation, nor have armed himself against his own children, for he would have in them the likeness of his own inherent wickedness. But since they, following after Me, laugh to scorn the deceitfulness of this world, and are out of the world, and, moreover, in their conduct show most clearly the impress of My incomparable holiness, and on that account have Satan, who is ever murmuring against the Saints, for their bitter foe, ever lying in wait for them; therefore of necessity I desire them to be in Thy safe keeping. And to be in Thy safe keeping is not to be far from Thy truth, that is, from Me. For I am by Nature Thy truth, O Father, the Essential, True, and Living Word.

We must suppose that this is what He thinks right to say. See how, in all His sayings, so to speak, He insinuates His own Person into the action of the Father, whatever that action has reference to, and puts Himself altogether side by side with Him, wishing probably to show how true the statement is: All things were made by Him; and without Him was not anything made. In the previous passage, indeed, He briefly besought His Father to keep the disciples in the Name which had been given unto Himself. In this, however, He desires His prayer on their behalf to be fulfilled in the truth of the Father. What, then, does this mean; or what does the change in the language signify? Is it meant to show that the working of the Father, shown through Him in mercy to the Saints, is not uniform? For in the first passage, when He says that His disciples ought to be kept in the Name of the Father, that is to say, in the glory and power of His Godhead, so that they should be out of the power of the enemy, He declares that aid is vouchsafed to the Saints in whatever happens unto them, after the secret fashion that Christ at the proper season revealed to His disciples when He said: Simon, Simon, behold, Satan asked to have you, that he might sift you as wheat: but I made supplication for thee, that thy fail not. For many of God's dealings concerning us are in secret, Christ taking thought for the life of each of us, and covering us as with a shield. But here, when He says Keep them in the truth, He signifies clearly their being led by revelation of the truth to apprehend it. For no man can attain to the knowledge of truth without the light of the Spirit, nor can he at all, humanly speaking, work out for himself an accurate comprehension of the Divine doctrines. For the mysteries of Holy Writ exceed our understanding, and glorious is the blessing of having even a moderate knowledge concerning Christ.

The blessed Peter, moreover, when he confessed that the Lord was in truth the Son of the living God, heard the words: Blessed art thou, Simon Bar-jona; for flesh and blood hath not revealed it unto thee, but My Father Which is in heaven. For He reveals to the Saints His Son, Who is truth, and does not allow Satan to lead the mind of His believers astray to false knowledge; relying on whom, in their season, Hymenaeus and Alexander have made shipwreck concerning the faith, rejecting the true doctrine of the faith. Of great avail, then, towards a right continuance in the straight path of thought and action, is our safe keeping by the Father in the Name of God and in truth; that we may not fail in making our light shine forth in action, nor, by turning aside to folly, stray far away from the doctrines of true holiness. And this may easily be our lot, if we are seen to be out of the world while not disavowing our birth in the world; for of the dust of the earth are we all framed, as the Scripture saith, but by the quality of our deeds we rid ourselves of life in the world. For while they walk upon earth, those who love conformity with Christ are citizens of heaven.

We must also remark that He very appropriately here calls the Father holy, almost, as it were, reminding Him that, as He is holy, He takes pleasure in those that are holy. And all men are holy, whosoever are seen to be unspotted by the world, and whosoever are by nature in Christ, in the Father's likeness adopted, and chosen to be His disciples by the sanctification according to grace, and the light and goodness of their lives. For a man may thus be conformed to the Image of God, Which transcends the world.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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