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Translation
King James Version
No man can serve two masters: for either he will hate the one, and love the other; or else he will hold to the one, and despise the other. Ye cannot serve God and mammon.
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KJV (with Strong's)
No man G3762 can G1410 serve G1398 two G1417 masters G2962: for G1063 either G2228 he will hate G3404 the one G1520, and G2532 love G25 the other G2087; or else G2228 he will hold G472 to the one G1520, and G2532 despise G2706 the other G2087. Ye cannot G3756 G1410 serve G1398 God G2316 and G2532 mammon G3126.
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Complete Jewish Bible
No one can be slave to two masters; for he will either hate the first and love the second, or scorn the second and be loyal to the first. You can't be a slave to both God and money.
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Berean Standard Bible
No one can serve two masters: Either he will hate the one and love the other, or he will be devoted to the one and despise the other. You cannot serve both God and money.
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American Standard Version
No man can serve two masters: for either he will hate the one, and love the other; or else he will hold to one, and despise the other. Ye cannot serve God and mammon.
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World English Bible Messianic
“No one can serve two masters, for either he will hate the one and love the other; or else he will be devoted to one and despise the other. You can’t serve both God and Mammon.
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Geneva Bible (1599)
No man can serue two masters: for eyther he shall hate the one, and loue the other, or els he shall leane to the one, and despise the other. Ye cannot serue God and riches.
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Young's Literal Translation
`None is able to serve two lords, for either he will hate the one and love the other, or he will hold to the one, and despise the other; ye are not able to serve God and Mammon.
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In the KJVVerse 23,307 of 31,102

Study This Verse

SUMMARY

Matthew 6:24 presents one of Jesus' most unequivocal declarations regarding ultimate allegiance, asserting the inherent impossibility of serving two competing masters—specifically, God and "mammon" (wealth personified). This profound statement underscores the exclusive nature of true devotion, revealing that the human heart cannot simultaneously give its supreme loyalty to both divine and material pursuits. It highlights an unavoidable choice, where one's affections and priorities will inevitably gravitate towards one master while diminishing the other, thereby exposing the true object of one's trust and service.

CONTEXT

  • Literary Context: This verse serves as the powerful culmination of a significant segment within Jesus' Sermon on the Mount, specifically following His teaching on genuine treasure (Matthew 6:19-21) and the "eye as the lamp of the body" (Matthew 6:22-23). Having established that one's treasure indicates the heart's true location, and that spiritual perception is vital, Jesus then delivers this absolute principle. It directly precedes and lays the groundwork for His subsequent exhortation against anxiety and worry about material needs in Matthew 6:25-34, demonstrating that divided loyalties are the root cause of such anxieties. The entire section is designed to reorient disciples' priorities from earthly accumulation to heavenly devotion.

  • Historical & Cultural Context: In the ancient world, the concept of "master" (Greek: kyrios) was deeply rooted in the institution of slavery or bonded servitude. A slave belonged entirely to one master, whose will was absolute and whose provision was the slave's sole reliance. The idea of serving two masters simultaneously was not merely impractical but legally and socially impossible; a slave could not divide their ultimate allegiance or render full obedience to two different owners. "Mammon" (Greek: mammonas) is a transliteration of an Aramaic word for wealth or property. While wealth itself was not inherently evil, the cultural context often saw it as a source of security, power, and status, tempting people to place their ultimate trust in it rather than in God. Jesus' teaching directly confronts this prevalent societal inclination to prioritize material gain.

  • Key Themes: The overarching theme is Exclusive Loyalty, emphasizing that God demands and deserves singular, undivided devotion. This verse powerfully articulates the Incompatibility of Masters, making it clear that God and "mammon" represent fundamentally opposing value systems and cannot coexist as supreme authorities in one's life. It underscores the Heart's True Allegiance, revealing that our actions, affections, and investments of time and resources ultimately expose whom we truly serve, aligning with Jesus' teaching that "where your treasure is, there your heart will be also" in Matthew 6:21. Furthermore, it serves as a profound Warning Against Materialism and Idolatry, cautioning against the subtle or overt ways in which the pursuit of worldly gain can usurp God's rightful place in a person's life, echoing warnings found throughout the Old Testament against serving other gods, such as in Deuteronomy 6:5.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • serve (Greek, douleúō, G1398): This verb means "to be a slave to" or "to render obedience to." It implies absolute submission, ownership, and devotion. It's not merely about performing tasks for someone, but about belonging to them entirely. A slave's life, resources, and will are completely at the disposal of their master.
  • masters (Greek, kýrios, G2962): From a root meaning "supremacy," this noun refers to one who is "supreme in authority," a "controller," or "Master." In this context, it signifies an owner or lord who holds ultimate authority and to whom one owes complete allegiance and obedience.
  • mammon (Greek, mammōnâs, G3126): Of Chaldee origin, this term refers to "confidence," specifically "wealth" or "avarice," which Jesus personifies here. It is not merely money or possessions, but the spirit of materialism, the pursuit of worldly gain, or the trust placed in wealth as a source of security, status, or ultimate fulfillment, thus setting it up as a rival deity.

Verse Breakdown

  • "No man can serve two masters:" This opening declaration is an absolute, non-negotiable truth, not a mere suggestion. The Greek word for "can" (dýnamai) signifies ability or possibility, making it clear that it is fundamentally impossible for a single individual to render full, undivided, and supreme allegiance to two different authorities simultaneously. The nature of "service" (slavery) demands exclusive devotion.
  • "for either he will hate the one, and love the other; or else he will hold to the one, and despise the other." This clause explains the inevitable outcome of attempting to divide ultimate loyalty. "Hate" (miséō) and "love" (agapáō) are used here in a comparative sense, indicating a preference or prioritization rather than emotional animosity. To "hate" one master means to love them less, to de-prioritize them, or to be less devoted to them. Conversely, "hold to" (antéchomai) implies adhering firmly, supporting, or caring for, while "despise" (kataphronéō) means to disesteem or think against. The parallelism emphasizes that a choice, whether conscious or unconscious, will always be made, resulting in a primary allegiance to one and a secondary, diminished, or rejected allegiance to the other.
  • "Ye cannot serve God and mammon." This is the direct application of the universal principle to the specific, critical choice facing humanity. "God" (Greek: theós) represents the supreme Divinity, the Creator and sustainer of all, who demands absolute worship and trust. "Mammon," as previously analyzed, embodies the spirit of worldly wealth and materialism when it becomes an object of ultimate trust or pursuit. Jesus explicitly states the utter incompatibility of these two masters, making it impossible to give ultimate devotion to both. One's life will inevitably be ordered around the values and demands of one or the other.

Literary Devices

Jesus employs several potent literary devices in Matthew 6:24 to convey His message with clarity and force. The primary device is Personification, where "mammon" (wealth) is treated not merely as a commodity but as a rival master or deity, capable of demanding service and allegiance. This elevates the pursuit of wealth to a spiritual battle, making it clear that it competes directly with God for the heart's devotion. Another key device is Antithesis, setting up a stark contrast between two opposing forces: God and mammon. This creates a clear, undeniable choice, highlighting the mutually exclusive nature of their demands. Furthermore, the use of strong verbs like "hate" and "love," "hold to" and "despise," while perhaps bordering on Hyperbole in their intensity, serves to emphasize the profound and unavoidable conflict of loyalties, making it impossible to remain neutral or serve both masters equally. The structure of the statement, moving from a general principle ("No man can serve two masters") to a specific, critical application ("Ye cannot serve God and mammon"), is a form of Deductive Reasoning, reinforcing the absolute nature of the truth being conveyed.

THEOLOGICAL AND THEMATIC CONNECTIONS

Matthew 6:24 is a foundational statement on the nature of worship and the exclusivity of God's claim on human hearts. Theologically, it asserts God's sovereignty and His demand for singular devotion, echoing the first commandment against having other gods before Him. It reveals that the pursuit of wealth, when it becomes an ultimate end or source of security, functions as an idol, directly challenging God's rightful place. This verse highlights the spiritual reality that our ultimate allegiance shapes our worldview, values, and life choices, demonstrating that divided loyalties inevitably lead to spiritual compromise and internal conflict. It calls for a radical reorientation of priorities, where God's kingdom and righteousness are sought above all else.

  • Deuteronomy 6:5: "And thou shalt love the LORD thy God with all thine heart, and with all thy soul, and with all thy might."
  • Luke 16:13: "No servant can serve two masters: for either he will hate the one, and love the other; or else he will hold to the one, and despise the other. Ye cannot serve God and mammon."
  • 1 Timothy 6:10: "For the love of money is the root of all evil: which while some coveted after, they have erred from the faith, and pierced themselves through with many sorrows."

REFLECTION AND APPLICATION

Matthew 6:24 serves as an enduring challenge to every believer, compelling us to honestly examine the true allegiances of our hearts. In a world saturated with consumerism and the relentless pursuit of material gain, Jesus' words cut through the noise, forcing us to confront whether our lives are genuinely ordered around God's will or the demands of wealth. This verse calls us to a radical re-evaluation of our priorities, asking where our time, energy, and deepest affections are truly invested. If we find ourselves experiencing internal conflict, anxiety, or a sense of spiritual compromise, it may be a direct result of attempting to navigate the impossible task of serving two masters. The path to spiritual freedom and peace lies in wholeheartedly choosing God as our sole Master, trusting Him for our provision, and aligning our lives with His kingdom values. This commitment liberates us from the tyranny of materialism and invites us into a life of undivided devotion, where true riches are found in Christ alone.

Questions for Reflection

  • What areas of my life reveal where my ultimate trust and security truly lie—in God or in material things?
  • How does the pursuit of wealth or possessions subtly (or overtly) compete with my devotion to God in my daily decisions?
  • Am I experiencing any inner conflict or "double-mindedness" that might stem from attempting to serve both God and mammon?
  • What practical steps can I take to reorient my priorities and more fully commit to serving God as my one true Master?

FAQ

Does "mammon" refer only to money, or something broader?

Answer: While "mammon" (Greek: mammōnâs) is often translated as "money" or "wealth," Jesus' use of it here, particularly in personifying it as a "master," indicates a broader meaning. It encompasses not just physical currency or possessions, but the entire system of worldly values, security, and trust that is placed in material things. It represents the spirit of materialism, greed, and the pursuit of earthly gain as an ultimate end or source of fulfillment. Therefore, serving "mammon" means placing one's ultimate trust, hope, and allegiance in wealth or worldly success rather than in God. It's about where one's heart finds its ultimate security, as Jesus teaches in Matthew 6:21.

CHRIST-CENTERED FULFILLMENT

Matthew 6:24, though a stark warning, finds its ultimate fulfillment and resolution in the person and work of Jesus Christ. He is the singular Master worthy of all devotion, demonstrating perfect, undivided allegiance to the Father. Unlike fallen humanity, who are prone to divided loyalties, Jesus lived a life utterly free from the allure of mammon, choosing poverty and dependence on God over worldly riches, as seen in His lack of a place to lay His head (Matthew 8:20). He perfectly embodied the principle of seeking first God's kingdom and righteousness (Matthew 6:33), showing that true security and provision come from the Father alone. Through His atoning sacrifice, Christ frees us from the bondage of sin, which includes the idolatry of mammon, enabling us to truly "serve God" by the power of the Holy Spirit. He calls us to follow Him, to take up our cross (Matthew 16:24), and to surrender all to Him, thereby making Him our sole Lord and Master. In Christ, the impossible becomes possible: we can genuinely serve God alone, for He has overcome the world and its deceptive allurements (John 16:33).

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Commentary on Matthew 6 verses 19–24

I. II. Main points1. 2. Sub-points

Worldly-mindedness is as common and as fatal a symptom of hypocrisy as any other, for by no sin can Satan have a surer and faster hold of the soul, under the cloak of a visible and passable profession of religion, than by this; and therefore Christ, having warned us against coveting the praise of men, proceeds next to warn us against coveting the wealth of the world; in this also we must take heed, lest we be as the hypocrites are, and do as they do: the fundamental error that they are guilty of is, that they choose the world for their reward; we must therefore take heed of hypocrisy and worldly-mindedness, in the choice we make of our treasure, our end, and our masters.

I. In choosing the treasure we lay up. Something or other every man has which he makes his treasure, his portion, which his heart is upon, to which he carries all he can get, and which he depends upon for futurity. It is that good, that chief good, which Solomon speaks of with such an emphasis, Ecc 2:3. Something the soul will have, which it looks upon as the best thing, which it has a complacency and confidence in above other things. Now Christ designs not to deprive us of our treasure, but to direct us in the choice of it; and here we have,

1.A good caution against making the things that are seen, that are temporal, our best things, and placing our happiness in them. Lay not up for yourselves treasures upon earth. Christ's disciples had left all to follow him, let them still keep in the same good mind. A treasure is an abundance of something that is in itself, at least in our opinion, precious and valuable, and likely to stand us in stead hereafter. Now we must not lay up our treasures on earth, that is, (1.) We must not count these things the best things, nor the most valuable in themselves, nor the most serviceable to us: we must not call them glory, as Laban's sons did, but see and own that they have no glory in comparison with the glory that excelleth. (2.) We must not covet an abundance of these things, nor be still grasping at more and more of them, and adding to them, as men do to that which is their treasure, as never knowing when we have enough. (3.) We must not confide in them for futurity, to be our security and supply in time to come; we must not say to the gold, Thou art my hope. (4.) We must not content ourselves with them, as all we need or desire: we must be content with a little for our passage, but not with all for our portion. These things must not be made our consolation (Luk 6:24), our good things, Luk 16:25. Let us consider we are laying up, not for our posterity in this world, but for ourselves in the other world. We are put to our choice, and made in a manner our own carvers; that is ours which we lay up for ourselves. It concerns thee to choose wisely, for thou art choosing for thyself, and shalt have as thou choosest. If we know and consider ourselves what we are, what we are made for, how large our capacities are, and how long our continuance, and that our souls are ourselves, we shall see it is foolish thing to lay up our treasures on earth.

2.Here is a good reason given why we should not look upon any thing on earth as our treasure, because it is liable to loss and decay: (1.) From corruption within. That which is treasure upon earth moth and rust do corrupt. If the treasure be laid up in fine clothes, the moth frets them, and they are gone and spoiled insensibly, when we thought them most securely laid up. If it be in corn or other eatables, as his was who had his barns full (Luk 12:16, Luk 12:17), rust (so we read it) corrupts that: brōsis - eating, eating by men, for as goods are increased they are increased that eat them (Ecc 5:11); eating by mice or other vermin; manna itself bred worms; or it grows mouldy and musty, is struck, or smutted, or blasted; fruits soon rot. Or, if we understand it of silver and gold, they tarnish and canker; they grow less with using, and grow worse with keeping (Jam 5:2, Jam 5:3); the rust and the moth breed in the metal itself and in the garment itself. Note, Worldly riches have in themselves a principal of corruption and decay; they wither of themselves, and make themselves wings. (2.) From violence without. Thieves break through and steal. Every hand of violence will be aiming at the house where treasure is laid up; nor can any thing be laid up so safe, but we may be spoiled of it. Numquam ego fortunae credidi, etiam si videretur pacem agere; omnia illa quae in me indulgentissime conferebat, pecuniam, honores, gloriam, eo loco posui, unde posset ea, since metu meo, repetere - I never reposed confidence in fortune, even if she seemed propitious: whatever were the favours which her bounty bestowed, whether wealth, honours, or glory, I so disposed of them, that it was in her power to recall them without occasioning me any alarm. Seneca. Consol. ad Helv. It is folly to make that our treasure which we may so easily be robbed of.

3.Good counsel, to make the joys and glories of the other world, those things not seen that are eternal, our best things, and to place our happiness in them. Lay up for yourselves treasures in heaven. Note, (1.) There are treasures in heaven, as sure as there are on this earth; and those in heaven are the only true treasures, the riches and glories and pleasures that are at God's right hand, which those that are sanctified truly arrive at, when they come to be sanctified perfectly. (2.) It is our wisdom to lay up our treasure in those treasures; to give all diligence to make sure our title to eternal life through Jesus Christ, and to depend upon that as our happiness, and look upon all things here below with a holy contempt, as not worthy to be compared with it. We must firmly believe there is such a happiness, and resolve to be content with that, and to be content with nothing short of it. If we thus make those treasures ours, they are laid up, and we may trust God to keep them safe for us; thither let us then refer all our designs, and extend all our desires; thither let us send before our best efforts and best affections. Let us not burthen ourselves with the cash of this world, which will but load and defile us, and be liable to sink us, but lay up in store good securities. The promises are bills of exchange, by which all true believers return their treasure to heaven, payable in the future state: and thus we make that sure that will be made sure. (3.) It is a great encouragement to us to lay up our treasure in heaven, that there it is safe; it will not decay of itself, no moth nor rust will corrupt it; nor can we be by force or fraud deprived of it; thieves do not break through and steal. It is a happiness above and beyond the changes and chances of time, an inheritance incorruptible.

4.A good reason why we should thus choose, and an evidence that we have done so (Mat 6:21), Where your treasure is, on earth or in heaven, there will you heart be. We are therefore concerned to be right and wise in the choice of our treasure, because the temper of our minds, and consequently the tenor of our lives, will be accordingly either carnal or spiritual, earthly or heavenly. The heart follows the treasure, as the needle follows the loadstone, or the sunflower the sun. Where the treasure is there the value and esteem are, there the love and affection are (Col 3:2), that way the desires and pursuits go, thitherward the aims and intents are levelled, and all is done with that in view. Where the treasure is, there our cares and fears are, lest we come short of it; about that we are most solicitous; there our hope and trust are (Pro 18:10, Pro 18:11); there our joys and delights will be (Psa 119:111); and there our thoughts will be, there the inward thought will be, the first thought, the free thought, the fixed thought, the frequent, the familiar thought. The heart is God's due (Pro 23:26), and that he may have it, our treasure must be laid up with him, and then our souls will be lifted up to him.

This direction about laying up our treasure, may very fitly be applied to the foregoing caution, of not doing what we do in religion to be seen of men. Our treasure is our alms, prayers, and fastings, and the reward of them; if we have done these only to gain the applause of men, we have laid up this treasure on earth, have lodged it in the hands of men, and must never expect to hear any further of it. Now it is folly to do this, for the praise of men we covet so much is liable to corruption: it will soon be rusted, and moth-eaten, and tarnished; a little folly, like a dead fly, will spoil it all, Ecc 10:1. Slander and calumny are thieves that break through and steal it away, and so we lose all the treasure of our performances; we have run in vain, and laboured in vain, because we misplaced our intentions in doing of them. Hypocritical services lay up nothing in heaven (Isa 58:3); the gain of them is gone, when the soul is called for, Job 27:8. But if we have prayed and fasted and given alms in truth and uprightness, with an eye to God and to his acceptance, and have approved ourselves to him therein, we have laid up that treasure in heaven; a book of remembrance is written there (Mal 3:16), and being there recorded, they shall be there rewarded, and we shall meet them again with comfort on the other side death and the grave. Hypocrites are written in the earth (Jer 17:13), but God's faithful ones have their names written in heaven, Luk 10:20. Acceptance with God is treasure in heaven, which can neither be corrupted nor stolen. His well done shall stand for ever; and if we have thus laid up our treasure with him, with him our hearts will be; and where can they be better?

II. We must take heed of hypocrisy and worldly-mindedness in choosing the end we look at. Our concern as to this is represented by two sorts of eyes which men have, a single eye and an evil eye, Mat 6:22, Mat 6:23. The expressions here are somewhat dark because concise; we shall therefore take them in some variety of interpretation. The light of the body is the eye, that is plain; the eye is discovering and directing; the light of the world would avail us little without this light of the body; it is the light of the eye that rejoiceth the heart (Pro 15:30), but what is that which is here compared to the eye in the body.

1.The eye, that is, the heart (so some) if that be single - haplous - free and bountiful (so the word is frequently rendered, as Rom 12:8; Co2 8:2, Co2 9:11, Co2 9:13; Jam 1:5, and we read of a bountiful eye, Pro 22:9). If the heart be liberally affected and stand inclined to goodness and charity, it will direct the man to Christian actions, the whole conversation will be full of light, full of evidences and instances of true Christianity, that pure religion and undefiled before God and the Father (Jam 1:27), full of light, of good works, which are our light shining before men; but if the heart be evil, covetous, and hard, and envious, griping and grudging (such a temper of mind is often expressed by an evil eye, Mat 20:15; Mar 7:22; Pro 23:6, Pro 23:7), the body will be full of darkness, the whole conversation will be heathenish and unchristian. The instruments of the churl are and always will be evil, but the liberal deviseth liberal things, Isa 32:5-8. If the light that is in us, those affections which should guide us to that which is good, be darkness, if these be corrupt and worldly, if there be not so much as good nature in a man, not so much as a kind disposition, how great is the corruption of a man, and the darkness in which he sits! This sense seems to agree with the context; we must lay up treasure in heaven by liberality in giving alms, and that not grudgingly but with cheerfulness, Luk 12:33; Co2 9:7. But these words in the parallel place do not come in upon any such occasion, Luk 11:34, and therefore the coherence here does not determine that to be the sense of them.

2.The eye, that is, the understanding (so some); the practical judgment, the conscience, which is to the other faculties of the soul, as the eye is to the body, to guide and direct their motions; now if this eye be single, if it make a true and right judgment, and discern things that differ, especially in the great concern of laying up the treasure so as to choose aright in that, it will rightly guide the affections and actions, which will all be full of the light of grace and comfort; but if this be evil and corrupt, and instead of leading the inferior powers, is led, and bribed, and biassed by them, if this be erroneous and misinformed, the heart and life must needs be full of darkness, and the whole conversation corrupt. They that will not understand, are said to walk on in darkness, Psa 82:5. It is sad when the spirit of a man, that should be the candle of the Lord, is an ignis fatuus: when the leaders of the people, the leaders of the faculties, cause them to err, for then they that are led of them are destroyed, Isa 9:16. An error in the practical judgment is fatal, it is that which calls evil good and good evil (Isa 5:20); therefore it concerns us to understand things aright, to get our eyes anointed with eye-salve.

3.The eye, that is, the aims and intentions; by the eye we set our end before us, the mark we shoot at, the place we go to, we keep that in view, and direct our motion accordingly; in every thing we do in religion; there is something or other that we have in our eye; now if our eye be single, if we aim honestly, fix right ends, and move rightly towards them, if we aim purely and only at the glory of God, seek his honor and favour, and direct all entirely to him, then the eye is single; Paul's was so when he said, To me to live is Christ; and if we be right here, the whole body will be full of light, all the actions will be regular and gracious, pleasing to God and comfortable to ourselves; but if this eye be evil, if, instead of aiming only at the glory of God, and our acceptance with him, we look aside at the applause of men, and while we profess to honour God, contrive to honour ourselves, and seek our own things under colour of seeking the things of Christ, this spoils all, the whole conversation will be perverse and unsteady, and the foundations being thus out of course, there can be nothing but confusion and every evil work in the superstructure. Draw the lines from the circumference to any other point but the centre, and they will cross. If the light that is in thee be not only dim, but darkness itself, it is a fundamental error, and destructive to all that follows. The end specifies the action. It is of the last importance in religion, that we be right in our aims, and make eternal things, not temporal, our scope, Co2 4:18. The hypocrite is like the waterman, that looks one way and rows another; the true Christian like the traveller, that has his journey's end in his eye. The hypocrite soars like the kite, with his eye upon the prey below, which he is ready to come down to when he has a fair opportunity; the true Christian soars like the lark, higher and higher, forgetting the things that are beneath.

III. We must take heed of hypocrisy and worldly-mindedness in choosing the master we serve, Mat 6:24. No man can serve two masters. Serving two masters is contrary to the single eye; for the eye will be to the master's hand, Psa 123:1, Psa 123:2. Our Lord Jesus here exposes the cheat which those put upon their own souls, who think to divide between God and the world, to have a treasure on earth, and a treasure in heaven too, to please God and please men too. Why not? says the hypocrite; it is good to have two strings to one's bow. They hope to make their religion serve their secular interest, and so turn to account both ways. The pretending mother was for dividing the child; the Samaritans will compound between God and idols. No, says Christ, this will not do; it is but a supposition that gain is godliness, Ti1 6:5. Here is,

1.A general maxim laid down; it is likely it was a proverb among the Jews, No man can serve two masters, much less two gods; for their commands will some time or other cross or contradict one another, and their occasions interfere. While two masters go together, a servant may follow them both; but when they part, you will see to which he belongs; he cannot love, and observe, and cleave to both as he should. If to the one, not to the other; either this or that must be comparatively hated and despised. This truth is plain enough in common cases.

2.The application of it to the business in hand. Ye cannot serve God and Mammon. Mammon is a Syriac word, that signifies gain; so that whatever in this world is, or is accounted by us to be, gain (Phi 3:7), is mammon. Whatever is in the world, the lust of the flesh, the lust of the eye, and the pride of life, is mammon. To some their belly is their mammon, and they serve that (Phi 3:19); to others their ease, their sleep, their sports and pastimes, are their mammon (Pro 6:9); to others worldly riches (Jam 4:13); to others honours and preferments; the praise and applause of men was the Pharisees' mammon; in a word, self, the unity in which the world's trinity centres, sensual, secular self, is the mammon which cannot be served in conjunction with God; for if it be served, it is in competition with him and in contradiction to him. He does not say, We must not or we should not, but we cannot serve God and Mammon; we cannot love both (Jo1 2:15; Jam 4:4); or hold to both, or hold by both in observance, obedience, attendance, trust, and dependence, for they are contrary the one to the other. God says, "My son, give me thy heart." Mammon says, "No, give it me." God says, "Be content with such things as ye have." Mammon says, "Grasp at all that ever thou canst. Rem, rem, quocunque modo rem - Money, money; by fair means or by foul, money." God says, "Defraud not, never lie, be honest and just in all thy dealings." Mammon says "Cheat thine own Father, if thou canst gain by it." God says, "Be charitable." Mammon says, "Hold thy own: this giving undoes us all." God says, "Be careful for nothing." Mammon says, "Be careful for every thing." God says, "Keep holy thy sabbath-day." Mammon says, "Make use of that day as well as any other for the world." Thus inconsistent are the commands of God and Mammon, so that we cannot serve both. Let us not then halt between God and Baal, but choose ye this day whom ye will serve, and abide by our choice.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 19–24. Public domain.
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TertullianAD 220
De Spectaculis
How many other undoubted proofs we have had in the case of persons who, by keeping company with the devil in the shows, have fallen from the Lord! For no one can serve two masters. What fellowship has light with darkness, life with death?
TertullianAD 220
To His Wife Book II
For who would doubt that faith undergoes a daily process of obliteration by unbelieving intercourse? "Evil confabulations corrupt good morals; " how much more fellowship of life, and indivisible intimacy! Any and every believing woman must of necessity obey God. And how can she serve two lords -the Lord, and her husband-a Gentile to boot? For in obeying a Gentile she will carry out Gentile practices,-personal attractiveness, dressing of the head, worldly elegancies, baser blandishments, the very secrets even of matrimony tainted: not, as among the saints, where the duties of the sex are discharged with honour (shown) to the very necessity (which makes them incumbent), with modesty and temperance, as beneath the eyes of God.
TertullianAD 220
A Treatise on the Soul
"Amongst other things," says she, "there has been shown to me a soul in bodily shape, and a spirit has been in the habit of appearing to me; not, however, a void and empty illusion, but such as would offer itself to be even grasped by the hand, soft and transparent and of an etherial colour, and in form resembling that of a human being in every respect.
TertullianAD 220
On Idolatry
"But I was under contract." "None can serve two lords." If you wish to be the Lord's disciple, it is necessary you "take your cross, and follow the Lord: " your cross; that is, your own straits and tortures, or your body only, which is after the manner of a cross.
TertullianAD 220
De Corona
So you see idolatry is not without its gain, selling, as it does, Christ for pieces of gold, as Judas did for pieces of silver. Will it be "Ye cannot serve God and mammon" to devote your energies to mammon, and to depart from God? Will it be "Render unto Caesar the things which are Caesar's, and unto God the things which are God's," not only not to render the human being to God, but even to take the denarius from Caesar? Is the laurel of the triumph made of leaves, or of corpses? Is it adorned with ribbons, or with tombs? Is it bedewed with ointments, or with the tears of wives and mothers? It may be of some Christians too; for Christ is also among the barbarians.
John ChrysostomAD 407
Homily on the Gospel of Matthew 21
Seest thou how by degrees He withdraws us from the things that now are, and at greater length introduces what He hath to say, touching voluntary poverty, and casts down the dominion of covetousness?

For He was not contented with His former sayings, many and great as they were, but He adds others also, more and more alarming.

For what can be more alarming than what He now saith, if indeed we are for our riches to fall from the service of Christ? or what more to be desired, if indeed, by despising wealth, we shall have our affection towards Him and our charity perfect? For what I am continually repeating, the same do I now say likewise, namely, that by both kinds He presses the hearer to obey His sayings; both by the profitable, and by the hurtful; much like an excellent physician, pointing out both the disease which is the consequence of neglect, and the good health which results from obedience.

See, for instance, what kind of gain He signifies this to be, and how He establishes the advantage of it by their deliverance from the contrary things. Thus, "wealth," saith He, "hurts you not in this only, that it arms robbers against you, nor in that it darkens your mind in the most intense degree, but also in that it casts you out of God's service, making you captive of lifeless riches, and in both ways doing you harm, on the one hand, by causing you to be slaves of what you ought to command; on the other, by casting you out of God's service, whom, above all things, it is indispensable for you to serve." For just as in the other place, He signified the mischief to be twofold, in both laying up here, "where moth corrupteth," and in not laying up there, where the watch kept is impregnable; so in this place, too, He shows the loss to be twofold, in that it both draws off from God, and makes us subject to mammon.

But He sets it not down directly, rather He establishes it first upon general considerations, saying thus; "No man can serve two masters:" meaning here two that are enjoining opposite things; since, unless this were the case, they would not even be two. For so, "the multitude of them that believed were of one heart and of one soul," and yet were they divided into many bodies; their unanimity however made the many one.

Then, as adding to the force of it, He saith, "so far from serving, he will even hate and abhor:" "For either he will hate the one," saith He, "and love the other, or else he will hold to the one and despise the other." And it seems indeed as if the same thing were said twice over; He did not however choose this form without purpose, but in order to show that the change for the better is easy. I mean, lest thou shouldest say, "I am once for all made a slave; I am brought under the tyranny of wealth," He signifies that it is possible to transfer one's self, and that as from the first to the second, so also from the second one may pass over to the first.
John ChrysostomAD 407
Homily on the Gospel of Matthew 21
Having thus, you see, spoken generally, that He might persuade the hearer to be an uncorrupt judge of His words, and to sentence according to the very nature of the things; when he hath made sure of his assent, then, and not till then, He discovers Himself. Thus He presently adds, "Ye cannot serve God and mammon." Let us shudder to think what we have brought Christ to say; with the name of God, to put that of gold. But if this be shocking, its taking place in our deeds, our preferring the tyranny of gold to the fear of God, is much more shocking.

"What then? Was not this possible among the ancients?" By no means. "How then," saith one, "did Abraham, how did Job obtain a good report?" Tell me not of them that are rich, but of them that serve riches. Since Job also was rich, but he served not mammon, but possessed it and ruled over it, and was a master, not a slave. Therefore he so possessed all those things, as if he had been the steward of another man's goods; not only not extorting from others, but even giving up his own to them that were in need. And what is more, when he had them they were no joy to him: so he also declared, saying, "If I did so much as rejoice when my wealth waxed great:" wherefore neither did he grieve when it was gone. But they that are rich are not now such as he was, but are rather in a worse condition than any slave, paying as it were tribute to some grievous tyrant. Because their mind is as a kind of citadel occupied by the love of money, which from thence daily sends out unto them its commands full of all iniquity, and there is none to disobey. Be not therefore thus over subtle. Nay, for God hath once for all declared and pronounced it a thing impossible for the one service and the other to agree. Say not thou, then, "it is possible." Why, when the one master is commanding thee to spoil by violence, the other to strip thyself of thy possessions; the one to be chaste, the other to commit fornication; the one to be drunken and luxurious, the other to keep the belly in subjection; the one again to despise the things that are, the other to be rivetted to the present; the one to admire marbles, and walls, and roofs, the other to contemn these, but to honor self-restraint: how is it possible that these should agree?

Now He calls mammon here "a master," not because of its own nature, but on account of the wretchedness of them that bow themselves beneath it. So also He calls "the belly a god," not from the dignity of such a mistress, but from the wretchedness of them that are enslaved: it being a thing worse than any punishment, and enough, before the punishment, in the way of vengeance on him who is involved in it. For what condemned criminals can be so wretched, as they who having God for their Lord, do from that mild rule desert to this grievous tyranny, and this when their act brings after it so much harm even here? For indeed their loss is unspeakable by so doing: there are suits, and molestations, and strifes, and toils, and a blinding of the soul; and what is more grievous than all, one falls away from the highest blessings; for such a blessing it is to be God's servant.
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
(Hom. xxi.) Or otherwise; in what had gone before He had restrained the tyranny of avarice by many and weighty motives, but He now adds yet more. Riches do not only harm us in that they arm robbers against us, and that they cloud our understanding, but they moreover turn us away from God's service. This He proves from familiar notions, saying, No man can serve two masters; two, He means, whose orders are contrary; for concord makes one of many. This is proved by what follows, for either he will hate the one. He mentions two, that we may see that change for the better is easy. For if one were to give himself up in despair as having been made a slave to riches, namely, by loving them, he may hence learn, that it is possible for him to change into a better service, namely, by not submitting to such slavery, but by despising it.
John ChrysostomAD 407
Homily on the Gospel of Matthew 28
These things any one may see happening now also, even many in the tombs possessed of evil spirits, whom nothing restrains from their madness; not iron, nor chain, nor multitude of men, nor advice, nor admonition, nor terror, nor threat, nor any other such thing.

For so when any man is dissolute, eager after all embraces, he differs not at all from the demoniac, but goes about naked like him, clad indeed in garments, but deprived of the true covering, and stripped of his proper glory; cutting himself not with stones, but with sins more hurtful than many stones. Who then shall be able to bind such a one? Who, to stay his unseemliness and frenzy, his way of never coming to himself, but forever haunting the tombs? For such are the resorts of the harlots, full of much evil savor, of much rottenness.

And what of the covetous man? Is he not like this? For who will be able ever to bind him? Are there not fears and daily threats, and admonitions, and counsels? Nay, all these bonds he bursts asunder; and if any one come to set him free, he adjures him that he may not be freed, accounting it the greatest torture not to be in torture: than which what can be more wretched? For as to that evil spirit, even though he despised men, yet he yielded to the command of Christ, and quickly sprang out of the man's body; but this man yields not even to His commandment. See at least how he daily hears Him saying, "Ye cannot serve God and mammon," and threatening hell, and the incurable torments, and obeys not: not that He is stronger than Christ, but because against our will Christ corrects us not. Therefore such men live as in desert places, though they be in the midst of cities. For who, that hath reason, would choose to be with such men? I for my part would sooner consent to dwell with ten thousand demoniacs, than with one diseased in this way.
JeromeAD 420
Commentary on Matthew
(Verse 24) You cannot serve God and wealth. Wealth is called mammon in the Syriac language. You cannot serve God and wealth. Let the greedy person hear this, let the person who is thought to be unable to serve both wealth and Christ hear this. And yet it did not say, the one who has wealth, but the one who serves wealth. For the servant of wealth guards the riches, like a servant; but the one who has shaken off the yoke of servitude distributes them, like a master.
Jerome (as quoted by Aquinas, AD 1274)AD 420
Catena Aurea by Aquinas
Mammon—riches are so termed in Syriac. Let the covetous man who is called by the Christian name, hear this, that he cannot serve both Christ and riches. Yet He said not, he who has riches, but, he who is the servant of riches. For he who is the slave of money, guards his money as a slave; but he who has thrown off the yoke of his slavery, dispenses them as a master.
Augustine of Hippo (as quoted by Aquinas, AD 1274)AD 430
Catena Aurea by Aquinas
(Serm. in Mont. ii. 14.) Whoso serves mammon, (that is, riches,) verily serves him, who, being for desert of his perversity set over these things of earth, is called by the Lord, The prince of this world. Or otherwise; who the two masters are He shows when He says, Ye cannot serve God and mammon, that is to say, God and the Devil. Either then man will hate the one, and love the other, namely God; or, he will endure the one and despise the other. For he who is mammon's servant endures a hard master; for ensnared by his own lust he has been made subject to the Devil, and loves him not. As one whose passions have connected him with another man's handmaid, suffers a hard slavery, yet loves not him whose handmaid he loves. But He said, will despise, and not will hate, the other, for none can with a right conscience hate God. But he despises, that is, fears Him not, as being certain of His goodness.
Augustine of HippoAD 430
SERMON ON THE MOUNT 2.14.48
“He will be devoted to one and disregard the other.” He does not say that one will hate the other, for scarcely anyone’s conscience could hate God. But one disregards God—that is to say, one does not fear God but presumes on his goodness. From this negligent and tormented confidence, the Holy Spirit recalls us when he says through the prophet: “Son, do not add sin to sin; and do not say, ‘The mercy of God is great.’ ” Note when Paul says, “Do you not know that God’s kindness is meant to lead you to repentance?” For whose mercy can be accounted as great as the mercy of him who forgives all, if they convert to him? He makes the wild olive a partaker of the fatness of the original olive tree. At the same time, whose severity can be accounted as great as the severity of him who has not spared the natural branches but has broken them off because of unbelief? Therefore, whoever wishes to love God and to beware of offending him, let such a one cleanse the upright intention of his heart from all duplicity. In this way, he will “think of the Lord in goodness and seek him in simplicity of heart.”
Augustine of HippoAD 430
Then, further, the statement which follows, No man can serve two masters, is to be referred to this very intent, as He goes on to explain, saying: For either he will hate the one, and love the other; or else he will submit to the one, and despise the other. And these words are to be carefully considered; for who the two masters are he immediately shows, when He says, You cannot serve God and mammon. Riches are said to be called mammon among the Hebrews. The Punic name also corresponds: for gain is called mammon in Punic. But he who serves mammon certainly serves him who, as being set over those earthly things in virtue of his perversity, is called by our Lord the prince of this world. A man will therefore either hate this one, and love the other, i.e. God; or he will submit to the one, and despise the other. For whoever serves mammon submits to a hard and ruinous master: for, being entangled by his own lust, he becomes a subject of the devil, and he does not love him; for who is there who loves the devil? But yet he submits to him; as in any large house he who is connected with another man's maid servant submits to hard bondage on account of his passion. even though he does not love him whose maid-servant he loves.

But he will despise the other, He has said; not, he will hate. For almost no one's conscience can hate God; but he despises, i.e. he does not fear Him, as if feeling himself secure in consideration of His goodness. From this carelessness and ruinous security the Holy Spirit recalls us, when He says by the prophet, My son, do not add sin upon sin, and say, The mercy of God is great; and, Do you not know that the patience of God invites you to repentance? For whose mercy can be mentioned as being so great as His, who pardons all the sins of those who return, and makes the wild olive a partaker of the fatness of the olive? And whose severity as being so great as His, who spared not the natural branches, but broke them off because of unbelief? But let not any one who wishes to love God, and to beware of offending Him, suppose that he can serve two masters; and let him disentangle the upright intention of his heart from all doubleness: for thus he will think of the Lord with a good heart, and in simplicity of heart will seek Him.
Pseudo-Chrysostom (as quoted by Aquinas, AD 1274)AD 500
Catena Aurea by Aquinas
The Lord had said above, that he that has a spiritual mind is able to keep his body free from sin; and that he who has not, is not able. Of this He here gives the reason, saying, No man can serve two masters.
Remigius of Rheims (as quoted by Aquinas, AD 1274)AD 533
Catena Aurea by Aquinas
(ap. Gloss. ord.) Otherwise; faith is likened to a light, because by it the goings of the inner man, that is, action, are lightened, that he should not stumble according to that, Thy word is a light to my feet. (Ps. 119:105.) If that then be pure and single, the whole body is light; but if defiled, the whole body will be dark. Yet otherwise; by the light may be understood the ruler of the Church, who may be well called the eye, as he it is that ought to see that wholesome things be provided for the people under him, which are understood by the body. If then the ruler of the Church err, how much more will the people subject to him err?
Theophylact of OhridAD 1107
What He means is this: no man can serve two lords who command things that are opposed to each other. Such lords are God and mammon. We make the devil our lord when we make the belly our god. But by nature and in truth God is the Lord, and mammon is unrighteousness.

Do you see that it is not possible for a rich man and unrighteous man to serve God? His love of money drives him away from God.
Theophylact of OhridAD 1107
No man can serve two lords:
What He means is this: no man can serve two lords who command things that are opposed to each other. Such lords are God and mammon. We make the devil our lord when we make the belly our god. But by nature and in truth God is the Lord, and mammon is unrighteousness.

Ye cannot serve God and mammon:
Do you see that it is not possible for a rich man and unrighteous man to serve God? His love of money drives him away from God.
Glossa Ordinaria (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(non occ.) Otherwise; it had been declared above, that good things become evil, when done with a worldly purpose. It might therefore have been said by some one, I will do good works from worldly and heavenly motives at once. Against this the Lord says, No man can serve two masters.

(non occ.) Or; He seems to allude to two different kinds of servants; one kind who serve freely for love, another who serve servilely from fear. If then one serve two masters of contrary character from love, it must be that he hate the one; if from fear, while he trembles before the one, he must despise the other. But as the world or God predominate in a man's heart, he must be drawn contrary ways; for God draws him who serves Him to things above; the earth draws to things beneath; therefore He concludes, Ye cannot serve God and mammon.

(ord.) By mammon is meant the Devil, who is the lord of money, not that he can bestow them unless where God wills, but because by means of them he deceives men.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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