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Translation
King James Version
How think ye? if a man have an hundred sheep, and one of them be gone astray, doth he not leave the ninety and nine, and goeth into the mountains, and seeketh that which is gone astray?
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KJV (with Strong's)
How G5101 think G1380 ye G5213? if G1437 G5100 a man G444 have G1096 an hundred G1540 sheep G4263, and G2532 one G1520 of G1537 them G846 be gone astray G4105, doth he G863 not G3780 leave G863 the ninety and nine G1768, and goeth G4198 into G1909 the mountains G3735, and seeketh G2212 that which G3588 is gone astray G4105?
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Complete Jewish Bible
"What's your opinion? What will somebody do who has a hundred sheep, and one of them wanders away? Won't he leave the ninety-nine on the hillsides and go off to find the stray?
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Berean Standard Bible
What do you think? If a man has a hundred sheep and one of them goes astray, will he not leave the ninety-nine on the hills and go out to search for the one that is lost?
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American Standard Version
How think ye? if any man have a hundred sheep, and one of them be gone astray, doth he not leave the ninety and nine, and go unto the mountains, and seek that which goeth astray?
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World English Bible Messianic
“What do you think? If a man has one hundred sheep, and one of them goes astray, doesn’t he leave the ninety-nine, go to the mountains, and seek that which has gone astray?
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Geneva Bible (1599)
How thinke ye? If a man haue an hundreth sheepe, and one of them be gone astray, doeth he not leaue ninetie and nine, and go into the mountaines, and seeke that which is gone astray?
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Young's Literal Translation
`What think ye? if a man may have an hundred sheep, and there may go astray one of them, doth he not--having left the ninety-nine, having gone on the mountains--seek that which is gone astray?
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In the KJVVerse 23,740 of 31,102

Study This Verse

SUMMARY

Matthew 18:12 introduces the profound Parable of the Lost Sheep, a pivotal illustration in Jesus' discourse on the value of every individual in God's kingdom. Through the relatable scenario of a shepherd diligently seeking one lost sheep out of a hundred, Jesus powerfully conveys the divine heart of God: His relentless compassion, His active pursuit of those who have wandered spiritually, and the immense worth He places on each soul, emphasizing that no one is insignificant or beyond His loving reach.

CONTEXT

  • Literary Context: This parable is embedded within Jesus' "Discourse on Humility and Forgiveness" in Matthew 18. The chapter begins with the disciples' question about who is greatest in the kingdom of heaven (Matthew 18:1). Jesus responds by emphasizing the necessity of childlike humility (Matthew 18:3-4), followed by a stern warning against causing "little ones" to stumble (Matthew 18:6-9). The parable of the lost sheep immediately follows the declaration that "it is not the will of your Father who is in heaven that one of these little ones should perish" (Matthew 18:10). Thus, the parable serves to illustrate the Father's active will and passionate pursuit of those who might be vulnerable or have strayed, reinforcing the immense value He places on each individual, particularly those who are marginalized or spiritually lost.

  • Historical & Cultural Context: Shepherding was a ubiquitous and highly respected profession in ancient Israel, deeply woven into the fabric of daily life and religious metaphor. Shepherds were known for their intimate knowledge of their flock, their protective instincts, and their willingness to endure hardship to care for their sheep. The image of a shepherd leaving the majority to find a single lost animal would have resonated strongly with Jesus' audience, who understood the dangers of the Judean wilderness—predators, treacherous terrain, and the risk of a lost sheep perishing quickly. This cultural understanding amplified the shepherd's dedication and the inherent vulnerability of the sheep, making the parable a powerful metaphor for God's relationship with humanity.

  • Key Themes: The Parable of the Lost Sheep in Matthew 18:12-14 powerfully underscores several core themes. Firstly, it highlights Divine Pursuit and Compassion, revealing God's active, relentless, and compassionate seeking of those who are lost or have strayed from His fold. This is not a passive waiting but an engaged, sacrificial search. Secondly, it emphasizes the Immeasurable Value of Every Individual Soul in God's eyes. The shepherd's willingness to risk the ninety-nine for the one demonstrates that no person is insignificant or expendable to God, directly connecting to Jesus' teaching about not despising "one of these little ones" in Matthew 18:10. Finally, the parable vividly portrays God's Heart of Rejoicing over Repentance, a theme further developed in the parallel account in Luke 15:7, where there is "more joy in heaven over one sinner who repents than over ninety-nine righteous persons who need no repentance."

EXPOSITION AND ANALYSIS

Key Word Analysis

  • think (Greek, dokéō', G1380): This word means "to think" or "to seem (truthfully or uncertainly)." Here, it functions as an invitation for the listener to consider and agree with the logical conclusion of the scenario Jesus presents. It prompts a reflective engagement with the parable's premise, drawing the audience into the shepherd's perspective.
  • gone astray (Greek, planáō', G4105): This verb means "to roam (from safety, truth, or virtue)," "to be led astray," "to err," or "to be deceived." It denotes a state of wandering, whether intentional or unintentional, implying vulnerability and danger. The sheep is not merely absent but has taken a wrong, perilous path, highlighting its need for rescue.
  • seeketh (Greek, zētéō', G2212): This word means "to seek" (literally or figuratively), "to desire," or "to endeavor." In this context, it describes the shepherd's active, determined, and purposeful search for the lost sheep. It signifies a diligent and persistent effort to recover that which is missing, underscoring the shepherd's commitment and love.

Verse Breakdown

  • "How think ye?": Jesus opens with a rhetorical question, inviting His audience to engage their reason and empathy. He appeals to their common understanding of a shepherd's responsibility and the value of his flock, setting the stage for a self-evident truth about divine care.
  • "if a man have an hundred sheep, and one of them be gone astray": This sets up the hypothetical but relatable scenario. The "hundred sheep" represent a complete flock, and the "one... gone astray" highlights the individual nature of the loss. The phrase "gone astray" emphasizes the sheep's vulnerable and lost condition, not merely a temporary absence but a deviation from the safe path.
  • "doth he not leave the ninety and nine, and goeth into the mountains, and seeketh that which is gone astray?": This is the heart of the parable's action. The shepherd's immediate and seemingly disproportionate response—leaving the secure majority to pursue the single lost one—underscores the immense value placed on the individual. The "mountains" suggest a difficult, dangerous, and solitary search, emphasizing the shepherd's sacrificial effort and relentless pursuit.

Literary Devices

The Parable of the Lost Sheep in Matthew 18:12 is rich in Allegory and Symbolism. The "man" or "shepherd" is an allegorical representation of God, specifically Jesus Himself, who is later identified as the Good Shepherd. The "hundred sheep" symbolize humanity, particularly those within God's care or potential care. The "one... gone astray" represents a lost soul, someone who has wandered from the path of righteousness or the community of faith. The act of "leaving the ninety and nine" and "going into the mountains" to "seek" the lost one symbolizes God's active, compassionate, and often sacrificial pursuit of individuals who are spiritually lost, demonstrating His immense love and determination to restore them. The rhetorical question format also employs Hypophora, where the speaker asks a question and then immediately answers it, guiding the audience to the intended conclusion about the shepherd's (and God's) nature.

THEOLOGICAL AND THEMATIC CONNECTIONS

Matthew 18:12 profoundly reveals the character of God as a diligent, compassionate, and actively seeking Shepherd, challenging any notion that God is indifferent to the plight of a single individual. This parable is a powerful testament to the immeasurable value God places on each human soul, emphasizing that His love extends even to those who have wandered furthest. It underscores the divine initiative in salvation, where God actively pursues the lost rather than passively waiting for them to return. This proactive love forms the foundation for understanding God's grace and His desire for all to come to repentance and salvation.

REFLECTION AND APPLICATION

The Parable of the Lost Sheep in Matthew 18:12 offers a deeply comforting and challenging message for believers today. For those who feel lost, overlooked, or insignificant, it serves as a profound assurance of God's personal and relentless love. It reminds us that no matter how far we may have strayed, God's heart yearns for our return, and He actively seeks us out. For those within the fold, it is a powerful call to embody the Shepherd's heart. It compels us to prioritize evangelism, not as a duty, but as an overflow of God's own passion for the lost. It also challenges us to care for the vulnerable within our communities and churches, to actively seek out those who are struggling, marginalized, or have fallen away, and to participate in the joyful work of restoration, reflecting the very nature of our heavenly Father.

Questions for Reflection

  • How does the shepherd's pursuit of the one lost sheep challenge your understanding of God's love for individuals?
  • In what ways might you be called to "seek" those who have "gone astray" in your own life or community?
  • What comfort does this parable offer to someone who feels distant from God or believes they are too far gone to be found?

FAQ

What is the main message of the Parable of the Lost Sheep?

Answer: The main message of the Parable of the Lost Sheep, particularly as presented in Matthew 18:12, is the immense value God places on every individual, especially those who are spiritually lost or vulnerable. It highlights God's active, compassionate, and relentless pursuit of the one who has strayed, demonstrating His desire for all to be found and restored. It underscores that no one is insignificant to Him, and He rejoices greatly when a lost soul is brought back into the fold, as further emphasized in Luke 15:7.

CHRIST-CENTERED FULFILLMENT

The Parable of the Lost Sheep in Matthew 18:12 finds its ultimate fulfillment in the person and work of Jesus Christ. He is the embodiment of the Shepherd who leaves the ninety-nine to seek and save the one. Jesus explicitly identifies Himself as the "Good Shepherd" in John 10:11, stating, "The good shepherd lays down his life for the sheep." This foreshadows His sacrificial death on the cross, the ultimate act of seeking and rescuing humanity from the lostness of sin. His entire earthly ministry, characterized by His compassion for sinners, His healing of the sick, and His teaching of the marginalized, exemplifies the Shepherd's tireless search. Through His atoning work, He gathers those who were scattered and brings them back into the Father's fold, fulfilling the very purpose of the shepherd in the parable: to ensure that "not one of these little ones should perish" (Matthew 18:14). Thus, Jesus is not just the teller of the parable but its living fulfillment, the One who actively seeks, finds, and restores His lost sheep.

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Commentary on Matthew 18 verses 1–35

I. II. Main points1. 2. Sub-points(1.) (2.) Details[1.] [2.] Fine details

As there never was a greater pattern of humility, so there never was a greater preacher of it, than Christ; he took all occasions to command it, to commend it, to his disciples and followers.

I. The occasion of this discourse concerning humility was an unbecoming contest among the disciples for precedency; they came to him, saying, among themselves (for they were ashamed to ask him, Mar 9:34), Who is the greatest in the kingdom of heaven? They mean not, who by character (then the question had been good, that they might know what graces and duties to excel in), but who by name. They had heard much, and preached much, of the kingdom of heaven, the kingdom of the Messiah, his church in this world; but ass yet they were so far from having any clear notion of it, that they dreamt of a temporal kingdom, and the external pomp and power of it. Christ had lately foretold his sufferings, and the glory that should follow, that he should rise again, from whence they expected his kingdom would commence; and now they thought it was time to put in for their places in it; it is good, in such cases, to speak early. Upon other discourses of Christ to that purport, debates of this kind arose (Mat 20:19, Mat 20:20; Luk 22:22, Luk 22:24); he spoke many words of his sufferings, but only one of his glory; yet they fasten upon that, and overlook the other; and, instead of asking how they might have strength and grace to suffer with him, they ask him, "Who shall be highest in reigning with him." Note, Many love to hear and speak of privileges and glory, who are willing to pass by the thoughts of work and trouble. They look so much at the crown, that they forget the yoke and the cross. So the disciples here did, when they asked, Who is the greatest in the kingdom of heaven?

1.They suppose that all who have a place in that kingdom are great, for it is a kingdom of priests. Note, Those are truly great who are truly good; and they will appear so at last, when Christ shall own them as his, though ever so mean and poor in the world.

2.They suppose that there are degrees in this greatness. All the saints are honourable, but not all alike so; one star differs from another star in glory. All David's officers were not worthies, nor all his worthies of the first three.

3.They suppose it must be some of them, that must be prime ministers of state. To whom should King Jesus delight to do honour, but to them who had left all for him, and were now his companions in patience and tribulation?

4.They strive who it should be, each having some pretence or other to it. Peter was always the chief speaker, and already had the keys given him; he expects to be lord-chancellor, or lord-chamberlain of the household, and so to be the greatest. Judas had the bag, and therefore he expects to be lord-treasurer, which, though now he come last, he hopes, will then denominate him the greatest. Simon and Jude are nearly related to Christ, and they hope to take place of all the great officers of state, as princes of the blood. John is the beloved disciple, the favourite of the Prince, and therefore hopes to be the greatest. Andrew was first called, and why should not he be first preferred? Note, We are very apt to amuse and humour ourselves with foolish fancies of things that will never be.

II. The discourse itself, which is a just rebuke to the question, Who shall be greatest? We have abundant reason to think, that if Christ ever intended that Peter and his successors at Rome should be heads of the church, and his chief vicars on earth, having so fair an occasion given him, he would now have let his disciples know it; but so far is he from this, that his answer disallows and condemns the thing itself. Christ will not lodge such an authority or supremacy any where in his church; whoever pretend to it are usurpers; instead of settling any of the disciples in this dignity, he warns them all not to put in for it.

Christ here teacheth them to be humble,

1.By a sign (Mat 18:2); He called a little child to him, and set him in the midst of them. Christ often taught by signs or sensible representations (comparisons to the eye), as the prophets of old. Note, Humility is a lesson so hardly learned, that we have need by all ways and means to be taught it. When we look upon a little child, we should be put in mind of the use Christ made of this child. Sensible things must be improved to spiritual purposes. He set him in the midst of them; not that they might play with him, but that they might learn by him. Grown men, and great men, should not disdain the company of little children, or think it below them to take notice of them. They may either speak to them, and give instruction to them; or look upon them, and receive instruction from them. Christ himself, when a child, was in the midst of the doctors, Luk 2:46.

2.By as sermon upon this sign; in which he shows them and us,

(1.)The necessity of humility, Mat 18:3. His preface is solemn, and commands both attention and assent; Verily I say unto you, I, the Amen, the faithful Witness, say it, Except ye be converted, and become as little children, ye shall not enter into the kingdom of heaven. Here observe,

[1.]What it is that he requires and insists upon.

First, "You must be converted, you must be of another mind, and in another frame and temper, must have other thoughts, both of yourselves and of the kingdom of heaven, before you be fit for a place in it. The pride, ambition, and affectation of honour and dominion, which appear in you, must be repented of, mortified, and reformed, and you must come to yourselves." Note, Besides the first conversion of a soul from a state of nature to a state of grace, there are after-conversions from particular paths of backsliding, which are equally necessary to salvation. Every step out of the way by sin, must be a step into it again by repentance. When Peter repented of his denying his Master, he was converted. Secondly, You must become as little children. Note, Converting grace makes us like little children, not foolish as children (Co1 14:20), nor fickle (Eph 4:14), nor playful (Mat 11:16); but, as children, we must desire the sincere milk of the word (Pe1 2:2); as children, we must be careful for nothing, but leave it to our heavenly Father to care for us (Mat 6:31); we must, as children, be harmless and inoffensive, and void of malice (Co1 14:20), governable, and under command (Gal 4:2); and (which is here chiefly intended) we must be humble as little children, who do not take state upon them, nor stand upon the punctilios of honour; the child of a gentleman will play with the child of a beggar (Rom 12:16), the child in rags, if it have the breast, is well enough pleased, and envies not the gaiety of the child in silk; little children have no great aims at great places, or projects to raise themselves in the world; they exercise not themselves in things too high for them; and we should in like manner behave, and quiet ourselves, Psa 131:1, Psa 131:2. As children are little in body and low in stature, so we must be little and low in spirit, and in our thoughts of ourselves. This is a temper which leads to other good dispositions; the age of childhood is the learning age.

[2.]What stress he lays upon this; Without this, you shall not enter into the kingdom of heaven. Note, Disciples of Christ have need to be kept in awe by threatenings, that they may fear lest they seem to come short, Heb 4:1. The disciples, when they put that question (Mat 18:1), thought themselves sure of the kingdom of heaven; but Christ awakens them to be jealous of themselves. They were ambitious of being greatest in the kingdom of heaven; Christ tells them, that, except they came to a better temper, they should never come thither. Note, many that set up for great ones in the church, prove not only little, but nothing, and are found to have no part or lot in the matter. Our Lord designs here to show the great danger of pride and ambition; whatever profession men make, if they allow themselves in this sin, they will be rejected both from God's tabernacle and from his holy hill. Pride threw the angels that sinned out of heaven, and will keep us out, if we be not converted from it. They that are lifted up with pride, fall into the condemnation of the devil; to prevent this, we must become as little children, and, in order to do that, must be born again, must put on the new man, must be like the holy child Jesus; so he is called, even after his ascension, Act 4:27.

(2.)He shows the honour and advancement that attend humility (Mat 18:4), thus furnishing a direct but surprising answer to their question. He that humbles himself as a little child, though he may fear that hereby he will render himself contemptible, as men of timid minds, who thereby throw themselves out of the way of preferment, yet the same is greatest in the kingdom of heaven. Note, The humblest Christians are the best Christians, and most like to Christ, and highest in his favour; are best disposed for the communications of divine grace, and fittest to serve God in this world, and enjoy him in another. They are great, for God overlooks heaven and earth, to look on such; and certainly those are to be most respected and honoured in the church that are most humble and self-denying; for, though they least seek it, they best deserve it.

(3.)The special care Christ takes for those that are humble; he espouses their cause, protects them, interests himself in their concerns, and will see that they are not wronged, without being righted.

Those that thus humble themselves will be afraid,

[1.]That nobody will receive them; but (Mat 18:5), Whoso shall receive one such little child in my name, receiveth me. Whatever kindnesses are done to such, Christ takes as done to himself. Whoso entertains a meek and humble Christian, keeps him in countenance, will not let him lose by his modesty, takes him into his love and friendship, and society and care, and studies to do him a kindness; and doth this in Christ's name, for his sake, because he bears the image of Christ, serves Christ, and because Christ has received him; this shall be accepted and recompensed as an acceptable piece of respect to Christ. Observe, Though it be but one such little child that is received in Christ's name, it shall be accepted. Note, The tender regard Christ has to his church extends itself to every particular member, even the meanest; not only to the whole family, but to every child of the family; the less they are in themselves, to whom we show kindness, the more there is of good will in it to Christ; the less it is for their sakes, the more it is for his; and he takes it accordingly. If Christ were personally among us, we think we should never do enough to welcome him; the poor, the poor in spirit, we have always with us, and they are his receivers. See Mat 25:35-40.

[2.]They will be afraid that every body will abuse them; the basest men delight to trample upon the humble; Vexat censura columbas - Censure pounces on doves. This objection he obviates (Mat 18:6), where he warns all people, as they will answer it at their utmost peril, not to offer any injury to one of Christ's little ones. This word makes a wall of fire about them; he that touches them, touches the apple of God's eye.

Observe, First, The crime supposed; offending one of these little ones that believe in Christ. Their believing in Christ, though they be little ones, unites them to him, and interests him in their cause, so that, as they partake of the benefit of his sufferings, he also partakes in the wrong of theirs. Even the little ones that believe have the same privileges with the great ones, for they have all obtained like precious faith. There are those that offend these little ones, by drawing them to sin (Co1 8:10, Co1 8:11), grieving and vexing their righteous souls, discouraging them, taking occasion from their mildness to make a prey of them in their persons, families, goods, or good name. Thus the best men have often met with the worst treatment in this world.

Secondly, The punishment of this crime; intimated in that word, Better for him that he were drowned in the depth of the sea. The sin is so heinous, and the ruin proportionably so great, that he had better undergo the sorest punishments inflicted on the worst of malefactors, which can only kill the body. Note, 1. Hell is worse than the depth of the sea; for it is a bottomless pit, and it is a burning lake. The depth of the sea is only killing, but hell is tormenting. We meet with one that had comfort in the depth of the sea, it was Jonah (Jon 2:2, Jon 2:4, Jon 2:9); but never any had the least grain or glimpse of comfort in hell, nor will have to eternity. 2. The irresistible irrevocable doom of the great Judge will sink sooner and surer, and bind faster, than a mill-stone hanged about the neck. It fixes a great gulf, which can never be broken through, Luk 16:26. Offending Christ's little ones, though by omission, is assigned as the reason of that dreadful sentence, Go ye cursed, which will at last be the doom of proud persecutors.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 1–35. Public domain.
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Hilary of Poitiers (as quoted by Aquinas, AD 1274)AD 367
Catena Aurea by Aquinas
The Angels offer daily to God the prayers of those that are to be saved by Christ; it is therefore perilous to despise him whose desires and requests are conveyed to the eternal and invisible God, by the service and ministry of Angels.

But by the one sheep is to be understood one man, and under this one man is comprehended the whole human race. He that seeks man is Christ, and the ninety and nine are the host of the heavenly glory which He left.
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
Or otherwise; As to shun the evil, so to honour the good, has great recompense. Above then He had bid them to cut off the friendships of those that gave offence, here He teaches them to show honour and service to the saints.

Or because the perfect are esteemed of many as little ones, as poor, namely, and despicable.

Here He is speaking not of any Angels, but of the higher sort; for when He says, Behold the face of my Father, He shows that their presence before God is free and open, and their honour great.

He gives yet another reason weightier than the foregoing, why the little ones are not to be despised, For the Son of Man is come to save that which was lost.

And to this reasoning He adds a parable, in which He sets forth the Father as seeking the salvation of men, and saying, What think you, If a man have a hundred sheep.
John ChrysostomAD 407
Homily on the Gospel of Matthew 59
"Take heed that ye despise not one of these little ones; for I say unto you, that their angels do always behold the face of my Father which is in Heaven."

He calleth little ones not them that are really little, but them that are so esteemed by the multitude, the poor, the objects of contempt, the unknown (for how should he be little who is equal in value to the whole world; how should he be little, who is dear to God?); but them who in the imagination of the multitude are so esteemed.

And He speaks not of many only, but even of one, even by this again warding off the hurt of the many offenses. For even as to flee the wicked, so also to honor the good, hath very great gain, and would be a twofold security to him who gives heed, the one by rooting out the friendships with them that offend, the other from regarding these saints with respect and honor.

Then in another way also He makes them objects of reverence, saying, "That their angels do always behold the face of my Father which is in Heaven."

Hence it is evident, that the saints have angels, or even all men. For the apostle too saith of the woman, "That she ought to have power on her head because of the angels." And Moses, "He set the bounds of the nations according to the number of the angels of God."

But here He is discoursing not of angels only, but rather of angels that are greater than others. But when He saith, "The face of my Father," He means nothing else than their fuller confidence, and their great honor.

"For the Son of Man is come to save that which was lost."

Again, He is putting another reason stronger than the former, and connects with it a parable, by which He brings in the Father also as desiring these things. "For how think ye?" saith He; "If a man have an hundred sheep, and one of them be gone astray, doth he not leave the ninety and nine, and goeth into the mountains, and seeketh that which is gone astray? And if so be that he find it, he rejoiceth over it more than over the ninety and nine, which went not astray. Even so it is not will before your Father, that one of these little ones should perish."

Seest thou by how many things He is urging to the care of our mean brethren. Say not then, "Such a one is a blacksmith, a shoemaker, he is a ploughman, he is a fool," and so despise him. For in order that thou shouldest not feel this, see by how many motives He persuades thee to practise moderation, and presses thee into a care for these. He set a little child, and saith, "Be ye as little children." And, "Whosoever receiveth such a little child receiveth me;" and, "Whosoever shall offend," shall suffer the utmost penalties. And He was not even satisfied with the comparison of the "millstone," but added also His "woe," and commanded us to cut off such, though they be in the place of hands and eyes to us. And by the angels again that are entrusted with these same mean brethren, He makes them objects of veneration, and from His own will and passion (for when He said, "The Son of Man is come to save that which was lost," He signifies even the cross, like as Paul saith, speaking of a brother, "For whom Christ died"); and from the Father, for that neither to Him doth it seem good that one should perish; and from common custom, because the shepherd leaves them that are safe, and seeks what is lost; and when he hath found what was gone astray, he is greatly delighted at the finding and the saving of this.

If then God thus rejoices over the little one that is found, how dost thou despise them that are the objects of God's earnest care, when one ought to give up even one's very life for one of these little ones? But is he weak and mean? Therefore for this very cause most of all, one ought to do everything in order to preserve him. For even He Himself left the ninety and nine sheep, and went after this, and the safety of so many availed not to throw into the shade the loss of one. But Luke saith, that He even brought it on his shoulders, and that "There was greater joy over one sinner that repenteth, than over ninety and nine just persons" And from His forsaking those that were saved for it, and from His taking more pleasure in this one, He showed His earnestness about it to be great.

Let us not then be careless about such souls as these. For all these things are said for this object. For by threatening, that he who has not become a little child should not so much as at all set foot in the Heavens, and speaking of "the millstone," He hath brought down the haughtiness of the boastful; for nothing is so hostile to love as pride; and by saying, "It must needs be that offenses come," He made them to be wakeful; and by adding, "Woe unto him by whom the offense cometh," He hath caused each to endeavor that it be not by him. And while by commanding to cut off them that offend He made salvation easy; by enjoining not to despise them, and not merely enjoining, but with earnestness (for "take heed," saith He, "that ye despise not one of these little ones"), and by saying, "Their angels behold the face of my Father," and, "For this end am I come," and "my Father willeth this," He hath made those who should take care of them more diligent.

Seest thou what a wall He hath set around them, and what earnest care He taketh of them that are contemptible and perishing, at once threatening incurable ills to them that make them fall, and promising great blessings to them that wait upon them, and take care of them, and bringing an example from Himself again and from the Father?

Him let us also imitate, refusing none of the tasks that seem lowly and troublesome for our brethren's sake; but though we have to do service, though he be small, though he be mean for whom this is done, though the work be laborious, though we must pass over mountains and precipices, let all things be held endurable for the salvation of our brother. For a soul is an object of such earnest care to God, that "He spared not His own Son."
JeromeAD 420
Commentary on Matthew
(Vers. 12, 13.) What do you think? If a man has a hundred sheep, and one of them goes astray, doth he not leave the ninety and nine in the mountains, and goeth to seek that which is gone astray? And if it so be that he findeth it: Amen I say to you, he rejoiceth more for that than for the ninety and nine that went not astray. In conclusion he calls to clemency one who had despatched him, saying: See that you do not despise one of these little ones, and he adds the parable of the ninety and nine sheep left in the mountains, and of the one that went astray, which the good shepherd, because of its great weakness, could not go after, and so he brought it back on his shoulder to the rest of the flock. Some think that he, who was in the form of God, yet did not consider equality with God something to be grasped, but emptied himself, taking the form of a servant, being obedient to the Father even unto death, even death on the cross (Philippians 2:6-8): and for this reason he descended to the earthly realm, to save the one lost sheep, that is, the human race. But others think that the number of ninety-nine sheep represents the righteous, and the one sheep, the sinner, as he said elsewhere: I have not come to call the righteous, but sinners: for it is not the healthy who need a doctor, but the sick (Luke 5:32). This parable in the Gospel according to Luke is written with two other parables, the parable of the ten drachmas and the parable of the two sons (Luke 15).
Jerome (as quoted by Aquinas, AD 1274)AD 420
Catena Aurea by Aquinas
The Lord had said, under the type of hand, foot, and eye, that all kin and connection which could afford scandal must be cut off. The harshness of this declaration He accordingly tempers with the following precept, saying, Take heed that ye despise not one of these little ones; i. e. As far as you may avoid despising them, but next to your own salvation seek also to heal them. But if ye see that they hold to their sins, it is better that ye be saved, than that ye perish in much company.

High dignity of souls, that each from its birth has an Angel set in charge over it!

Others think that by the ninety and nine sheep are understood the number of the righteous, and by the one sheep the sinners, according to that said in another place, I am not come to call the righteous but sinners to repentance. (Matt. 9:13.)

What follows, Even so it is not the will, &c. is to be referred to what was said above, Take heed that ye despise not one of these little ones; and so He shows that this parable was set forth to enforce that same saying. Also in saying, It is not the will of my Father which is in heaven that one of these little ones should perish, He shows that so oft as one of these little ones does perish, it is not by the Father's will that it perishes.
JeromeAD 420
COMMENTARY ON MATTHEW 3.18.12
When he said, “See that you do not despise one of these little ones,” he is calling us to be merciful. Then he adds the parable of the ninety-nine sheep left in the mountains and the one stray that because of its great weakness could not walk. The good shepherd carried it on his shoulders to the rest of the flock. This, some say, is the shepherd “who, though he was in the form of God, did not count equality with God a thing to be grasped but emptied himself, taking the form of a servant, being born in the likeness of men. And being found in human form he humbled himself and became obedient unto death, even death on a cross.” For that reason he descended to earth: to save the one sheep that had perished, that is, the human race. Others think that by the ninety-nine sheep should be understood the number of the righteous and by the one sheep the number of the sinners, according to what he said in another place: “I have come not to call the righteous but the sinners; for it is not the healthy who have need of the physician but those who are ill.”
Remigius of Rheims (as quoted by Aquinas, AD 1274)AD 533
Catena Aurea by Aquinas
As much as to say, Despise not little ones, for I also for men condescended to become man. By that which was lost, understand the human race; for all the elements have kept their place, but man was lost, because he has broken his ordained place.
Gregory the DialogistAD 604
Forty Gospel Homilies, Homily 34
"Which of you, having a hundred sheep, if he loses one of them, does he not leave the ninety-nine in the desert and go after the one that was lost?" Behold, with wonderful dispensation of mercy, the Truth gave a similitude which man might recognize in himself, and yet which pertained especially to the very author of mankind. For since one hundred is a perfect number, he himself had a hundred sheep when he created the substance of angels and men. But one sheep was lost when man, by sinning, abandoned the pastures of life. He left the ninety-nine sheep in the desert because he left those supreme choirs of angels in heaven. But why is heaven called a desert, unless because desert means abandoned? For man abandoned heaven when he sinned. The ninety-nine sheep remained in the desert while the Lord was seeking one on earth, because the number of rational creatures, namely of angels and men, which had been created to see God, was diminished by the perishing of man, and so that the perfect sum of sheep might be made whole in heaven, lost man was being sought on earth. For what this evangelist calls "in the mountains," signifies in the heights, because indeed the sheep that had not perished stood in the lofty places.
Gregory the Dialogist (as quoted by Aquinas, AD 1274)AD 604
Catena Aurea by Aquinas
(Hom. in Ev. 34. 12) But Dionysius says, that it is from the ranks of the lesser Angels that these are sent to perform this ministry, either visibly or invisibly, for that those higher ranks have not the employment of an outward ministry.

(Mor. ii. 3.) And therefore the Angels always behold the face of the Father, and yet they come to us, for by a spiritual presence they come forth to us, and yet by internal contemplation keep themselves there whence they come forth; for they come not so forth from the divine vision, as to hinder the joys of inward contemplation.

(Hom. in Ev. xxxiv. 3.) This refers to the Creator of man Himself; for a hundred is a perfect number, and He had a hundred sheep when He created the substance of Angels and men.

(ubi sup.) The Evangelist says they were left on the mountains, to signify that the sheep which were not lost abode on high.

(ubi sup.) We must consider whence it is that the Lord declares that He has joy rather over the converted sinners, than over the righteous that stand. Because these last are often slothful and slack to practise the greater good works, as being very secure within themselves, for that they have committed none of the heavier sins. While on the other hand those who have their wicked deeds to remember, do often through the compunction of sorrow glow with the more heat in their love of God, and when they think how they have strayed from Him, they replace their former losses by gains following. So the general in a battle loves best that soldier who turns in his flight and courageously presses the enemy, than him who never turned his back, yet never did any valorous deed. Yet there be some righteous over whom is joy so great, that no penitent can be preferred before them, those, who though not conscious to themselves of sins, yet reject things lawful, and humble themselves in all things. How great is the joy when the righteous mourns, and humbles himself, if there be joy when the unrighteous condemns himself wherein he has done amiss?
Bede (as quoted by Aquinas, AD 1274)AD 735
Catena Aurea by Aquinas
(ap. Anselm.) The Lord found the sheep when He restored man, and over that sheep that is found there is more joy in heaven than over the ninety and nine, because there is a greater matter for thanksgiving to God in the restoration of man than in the creation of the Angels. Wonderfully are the Angels made, but more wonderfully man restored.

(ap. Anselm.)f; Or, By the ninety-nine sheep, which He left on the mountains, are signified the proud to whom a unit is still wanting for perfection. When then He has found the sinner, He rejoices over him, that is, He makes his own to rejoice over him, rather than over the false righteous.
Rabanus Maurus (as quoted by Aquinas, AD 1274)AD 856
Catena Aurea by Aquinas
Note, that nine wants only one to make it ten, and ninety and nine the same to be a hundred. Thus members which want one only to be perfect, may be larger or smaller, but yet the unit remaining invariable, when it is added makes the rest perfect. And that the number of sheep might be made up perfect in heaven, lost man was sought on earth.
Glossa Ordinaria (as quoted by Aquinas, AD 1274)AD 1274
Catena Aurea by Aquinas
(ap. Anselm.) Or otherwise; Because so great evils come of brethren being scandalized, Take heed that ye despise not one of these little ones.

(ap. Anselm.) Therefore are they not to be despised for that they are so dear to God, that Angels are deputed to be their guardians; For I say unto you, that in heaven their Angels do always behold the face of my Father which is in heaven.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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