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“Paul’s Example of Faithful Endurance”· 2 Timothy 3:10–13
Translation
King James Version
Yea, and all that will live godly in Christ Jesus shall suffer persecution.
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KJV (with Strong's)
Yea G1161, and G2532 all G3956 that will G2309 live G2198 godly G2153 in G1722 Christ G5547 Jesus G2424 shall suffer persecution G1377.
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Complete Jewish Bible
And indeed, all who want to live a godly life united with the Messiah Yeshua will be persecuted,
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Berean Standard Bible
Indeed, all who desire to live godly lives in Christ Jesus will be persecuted,
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American Standard Version
Yea, and all that would live godly in Christ Jesus shall suffer persecution.
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World English Bible Messianic
Yes, and all who desire to live godly in Messiah Yeshua will suffer persecution.
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Geneva Bible (1599)
Yea, and all that will liue godly in Christ Iesus, shall suffer persecution.
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Young's Literal Translation
and all also who will to live piously in Christ Jesus shall be persecuted,
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In the KJVVerse 29,866 of 31,102 · 96.0%

Study This Verse

Summary

Second Timothy 3:12 presents a foundational and often challenging truth for believers across all generations: a life authentically devoted to God, lived in genuine union with Christ Jesus, is inextricably linked to the experience of suffering and opposition. This verse serves as both a sober warning and a profound assurance, establishing persecution not as an anomaly, but as an expected and even defining characteristic of true godliness in a world fundamentally opposed to divine truth and righteousness.

Context

Literary Context

This verse is strategically placed within Paul's final, poignant letter to his spiritual son, Timothy. It immediately follows Paul's somber prophecy regarding the "perilous times" of the last days, characterized by widespread moral depravity and apostasy (2 Timothy 3:1-5). Paul then contrasts this societal decay with his own unwavering example of steadfast faith, endurance, and suffering for the gospel (2 Timothy 3:10-11). Verse 12 functions as a universal principle, explaining why Paul experienced such persecution and why Timothy, and indeed all true believers, should expect similar opposition. It transitions from a description of wicked people to the inevitable conflict between their ungodliness and the godliness of Christ's followers.

Historical & Cultural Context

Paul wrote 2 Timothy from a Roman prison, likely during Nero's reign, a period marked by intense persecution of Christians. Nero famously blamed Christians for the Great Fire of Rome in 64 AD, initiating widespread and brutal oppression. Early Christians faced societal suspicion, accusations of atheism (for rejecting Roman gods), cannibalism (misunderstanding the Eucharist), and disloyalty (for refusing emperor worship). Their counter-cultural ethics, exclusive claims about Christ, and refusal to participate in pagan rituals made them targets. Paul himself was a prime example of this reality, having suffered numerous beatings, imprisonments, and shipwrecks, as detailed in 2 Corinthians 11:23-27. This historical backdrop underscores the practical, lived reality of persecution that Paul and his audience understood intimately.

Key Themes

The overarching themes in 2 Timothy 3 include the perilous nature of the last days, the importance of steadfastness in faith, the authority and sufficiency of Scripture (2 Timothy 3:16-17), and the inevitability of suffering for Christ. Verse 12 directly contributes to the theme of suffering, establishing it as a universal and expected consequence of genuine godliness, rather than an exception. It reinforces the idea that true discipleship involves a willingness to bear the cross, echoing Jesus' own teachings about the cost of following Him (Luke 9:23). This theme serves to prepare and strengthen believers for the opposition they will undoubtedly face.

Exposition and Analysis

Key Word Analysis

godly eusebōs' G2153

This adverb, derived from the adjective eusebēs, means "piously," "reverently," or "devoutly." It describes a life characterized by true reverence and devotion toward God, which is expressed not merely in outward religious observances but in an inner disposition that manifests in righteous and holy living. It implies a life lived in accordance with divine will and character, reflecting genuine piety.

in en' G1722

This primary preposition denotes a fixed position, state, a sphere. In the context of "in Christ Jesus," it signifies a deep, vital, and spiritual union. It's not merely being "with" Christ or "for" Christ, but being rooted in, united with, and sustained by Christ. This union is the source and sphere of the believer's new life, implying that true godliness is not self-generated but flows from this intimate relationship.

persecution diṓkō' G1377

The verb diṓkō primarily means "to pursue," often with hostile intent. By implication, it means "to persecute." The KJV translates it as "shall suffer persecution," capturing the passive experience of being pursued or oppressed. This word encompasses various forms of hostility, from verbal abuse and social ostracism to physical violence and even martyrdom. It signifies an active, often relentless, opposition directed against someone.

Verse Breakdown

"Yea, and all that will live godly"

The opening "Yea, and" (G1161 and G2532 kaí) emphasizes the strong affirmation and universal scope of the statement. "All" (G3956 pâs) signifies that this truth applies to every single individual who chooses ("will," G2309 thélō) to actively pursue and embody a life of piety and devotion to God ("live godly," G2198 záō and G2153 eusebōs). This is not a passive state but an intentional, active commitment to holy living.

"in Christ Jesus"

This crucial phrase defines the sphere and source of true godliness. It is not godliness achieved through human effort or legalistic observance, but a life that is lived in union with Christ. This union implies that Christ is the very foundation, power, and pattern for the believer's godly walk. It is precisely this identification with and embodiment of Christ's character that provokes the world's antagonism.

"shall suffer persecution"

The verb "shall suffer persecution" (G1377 diṓkō, in the future tense with a passive implication) is a definitive and unavoidable statement. It is not a possibility or a likelihood, but an absolute certainty. The consequence of living a godly life in Christ Jesus is the experience of opposition, hostility, and affliction from a world that stands opposed to God and His kingdom. This persecution is a direct result of the contrast between divine righteousness and worldly unrighteousness.

Literary Devices

The verse employs several powerful literary devices. Hyperbole is present in the word "all," emphasizing the universal nature of this truth for every genuine believer, leaving no exceptions. The strong, declarative statement "shall suffer persecution" functions as a prophecy or an absolute declaration, underscoring the certainty of this outcome. There is also a stark contrast implied between the "godly" life lived "in Christ Jesus" and the "persecution" it inevitably attracts, highlighting the inherent conflict between the kingdom of God and the kingdom of the world. Furthermore, the phrase "in Christ Jesus" is a key example of Pauline idiom, a unique theological shorthand that encapsulates the profound mystical union between the believer and Christ, serving as a powerful symbol of identity and belonging.

Theological and Thematic Connections

The theological implications of 2 Timothy 3:12 are profound, asserting that suffering for righteousness is not an anomaly but an inherent aspect of genuine Christian discipleship. It reveals a fundamental clash between the values of God's kingdom and the fallen world system. This verse underscores the reality that a life transformed by Christ, reflecting His holiness and truth, will inevitably expose the darkness of the world, leading to opposition. Far from being a sign of God's displeasure, persecution is paradoxically a mark of authentic faith, aligning believers with the experiences of Christ Himself and the prophets who came before them. It calls believers to a realistic expectation of hardship, fostering resilience and a deeper reliance on God's grace in the face of adversity.

Reflection and Application

This verse serves as both a sobering warning and a profound source of encouragement for believers today. In a culture that often prioritizes comfort and acceptance, 2 Timothy 3:12 challenges us to examine the authenticity of our faith. If our lives are truly "godly in Christ Jesus," marked by righteousness, truth, and a counter-cultural commitment to His ways, then some form of opposition—whether social ostracism, ridicule, professional disadvantage, or even outright hostility—is to be expected. This truth should not discourage us, but rather prepare us, strengthening our resolve to stand firm. It reminds us that our suffering is not in vain, but aligns us with Christ and the countless faithful witnesses throughout history who have endured for His name. It calls us to cultivate a robust faith that is ready to endure hardship, knowing that such trials refine our character and deepen our reliance on God.

Questions for Reflection

  1. In what ways might my pursuit of "godliness in Christ Jesus" lead to opposition or discomfort in my current environment?
  2. How does my understanding of persecution, as presented in this verse, shape my expectations for the Christian life?
  3. If I experience no friction or opposition for my faith, what might that indicate about the distinctiveness of my "godly" living "in Christ Jesus"?
  4. How can I better prepare myself spiritually and emotionally to endure potential persecution for the sake of Christ?

FAQ

Does "all that will live godly" mean only some Christians will be persecuted?

The phrase "all that will live godly" (KJV) or "all who desire to live godly" (ESV) refers to every true believer who genuinely commits to a life of piety and devotion to God, rooted in their union with Christ. It's not a subset of Christians, but rather a description of what it means to be a genuine Christian. The verse asserts that every person who truly embodies this commitment shall suffer persecution. The "will" (G2309 thélō) here implies a desire, an active choice, or an inclination to live in this manner. Therefore, the verse suggests that the experience of persecution is a universal consequence for all who sincerely pursue Christ-like godliness, not just a select few. The form of persecution may vary (from subtle social pressure to overt violence), but the principle of opposition remains constant for those who truly live for Christ.

Christ-Centered Fulfillment

Second Timothy 3:12 finds its ultimate fulfillment and deepest meaning in the person and work of Jesus Christ. He is the quintessential example of one who lived perfectly godly "in Christ Jesus"—indeed, He is Christ Jesus—and He suffered the most profound persecution imaginable. Jesus Himself warned His disciples that if the world hated Him, it would also hate them (John 15:18-20). His life, from the manger to the cross, was a testament to the truth that perfect godliness attracts the world's enmity. The persecution believers face is not a random misfortune, but a participation in the sufferings of Christ (Philippians 3:10), a confirmation of their union with Him. By enduring persecution, believers are conformed to the image of the suffering Servant, Jesus, who endured the cross "for the joy that was set before him" (Hebrews 12:2). Thus, the promise of persecution is paradoxically a call to deeper identification with Christ, assuring us that our trials align us with the very path our Savior trod, leading ultimately to glory with Him (Romans 8:17).

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Public-domain commentary

Matthew Henry

From his Commentary on the Whole Bible. Henry comments on passages, not single verses — this entry covers 2 Timothy 3:10–17. His four-level outline is real structure in the source text, so it is rendered as structure.

1662–1714 · 8 verses
Passage under comment2 Timothy 3:10–17
I. II. Main points1. 2. Sub-points(1.) (2.) Details[1.] [2.] Fine details

Here the apostle, to confirm Timothy in that way wherein he walked,

I.Sets before him his own example, which Timothy had been an eye-witness of, having long attended Paul (Ti2 3:10):

Thou hast fully known my doctrine. The more fully we know the doctrine of Christ and the apostles, the more closely we shall cleave to it; the reason why many sit loose to it is because they do not fully know it. Christ's apostles had no enemies but those who did not know them, or not know them fully; those who knew them best loved and honoured them the most. Now what is it that Timothy had so fully known in Paul?

1.The doctrine that he preached. Paul kept back nothing from his hearers, but declared to them the whole counsel of God (Act 20:27), so that if it were not their own fault they might fully know it. Timothy had a great advantage in being trained up under such a tutor, and being apprised of the doctrine he preached.

2.He had fully known his conversation: Thou hast fully know my doctrine, and manner of life; his manner of life was of a piece with his doctrine, and did not contradict it. He did not pull down by his living what he built up by his preaching. Those ministers are likely to do good, and leave lasting fruits of their labours, whose manner of life agrees with their doctrine; as, on the contrary, those cannot expect to profit the people at all that preach well and live ill.

3.Timothy fully knew what was the great thing that Paul had in view, both in his preaching and in his conversation: "Thou hast known my purpose, what I drive at, how far it is from any worldly, carnal, secular design, and how sincerely I aim at the glory of God and the good of the souls of men." 4. Timothy fully knew Paul's good character, which he might gather from his doctrine, manner of life, and purpose; for he gave proofs of his faith (that is, of his integrity and fidelity, or his faith in Christ, his faith concerning another world, by which Paul lived), his long-suffering towards the churches to which he preached and over which he presided, his charity towards all men, and his patience. These were graces that Paul was eminent for, and Timothy knew it. 5. He knew that he had suffered ill for doing well (Ti2 3:11): "Thou hast fully known the persecutions and afflictions that came unto me" (he mentions those only which happened to him while Timothy was with him, at Antioch, at Iconium, at Lystra); "and therefore let it be no surprise to thee if thou suffer hard things, it is no more than I have endured before." 6. He knew what care God had taken of him: Notwithstanding out of them all the Lord delivered me; as he never failed his cause, so his God never failed him. Thou hast fully known my afflictions. When we know the afflictions of good people but in part, they are a temptation to us to decline that cause which they suffer for; when we know only the hardships they undergo for Christ, we may be ready to say, "We will renounce that cause that is likely to cost us so dear in the owning of it;" but when we fully know the afflictions, not only how they suffer, but how they are supported and comforted under their sufferings, then, instead of being discouraged, we shall be animated by them, especially considering that we are told before that we must count upon such things (Ti2 3:12): All that will live godly in Christ Jesus shall suffer persecution: not always alike; at that time those who professed the faith of Christ were more exposed to persecution than at other times; but at all times, more or less, those who will live godly in Christ Jesus shall suffer persecution. They must expect to be despised, and that their religion will stand in the way of their preferment; those who will live godly must expect it, especially those who will live godly in Christ Jesus, that is, according to the strict rules of the Christian religion, those who will wear the livery and bear the name of the crucified Redeemer. All who will show their religion in their conversation, who will not only be godly, but live godly, let them expect persecution, especially when they are resolute in it. Observe,

(1.)The apostle's life was very exemplary for three things: for his doctrine, which was according to the will of God; for his life, which was agreeable to his doctrine; and for his persecutions and sufferings.

(2.)Though his life was a life of great usefulness, yet it was a life of great sufferings; and none, I believe, came nearer to their great Master for eminent services and great sufferings than Paul: he suffered almost in every place; the Holy Ghost witnessed that bonds and afflictions did abide him, Act 20:23. Here he mentions his persecutions and afflictions at Antioch, at Iconium, at Lystra, besides what he suffered elsewhere.

(3.)The apostle mentions the Lord's delivering him out of them all, for Timothy's and our encouragement under sufferings.

(4.)We have the practice and treatment of true Christians: they live godly in Jesus Christ - this is their practice; and they shall suffer persecution - this is the usage they must expect in this world.

II.He warns Timothy of the fatal end of seducers, as a reason why he should stick closely to the truth as it is in Jesus:

But evil men and seducers shall wax worse and worse, etc., Ti2 3:13. Observe, As good men, by the grace of God, grow better and better, so bad men, through the subtlety of Satan and the power of their own corruptions, grow worse and worse. The way of sin is down-hill; for such proceed from bad to worse, deceiving and being deceived. Those who deceive others do but deceive themselves; those who draw others into error run themselves into more and more mistakes, and they will find it so at last, to their cost.

III.He directs him to keep close to a good education, and particularly to what he had learned out of the holy scriptures (Ti2 3:14, Ti2 3:15):

Continue thou in the things which thou hast learned. Note, It is not enough to learn that which is good, but we must continue in it, and persevere in it unto the end. Then are we Christ's disciples indeed, Joh 8:31. We should not be any more children, tossed to and fro, and carried about with every wind of doctrine, by the sleight of men and cunning craftiness, whereby they lie in wait to deceive, Eph 4:14. Be not carried about with divers and strange doctrines; for it is a good thing that the heart be established with grace, Heb 13:9. And for this reason we should continue in the things we have learned from the holy scriptures; not that we ought to continue in any errors and mistakes which we may have been led into, in the time of our childhood and youth (for these, upon an impartial enquiry and full conviction, we should forsake); but this makes nothing against our continuing in those things which the holy scriptures plainly assert, and which he that runs may read. If Timothy would adhere to the truth as he had been taught it, this would arm him against the snares and insinuations of seducers. Observe, Timothy must continue in the things which he had learned and had been assured of.

1.It is a great happiness to know the certainty of the things wherein we have been instructed (Luk 1:4); not only to know what the truths are, but to know that they are of undoubted certainty. What we have learned we must labour to be more and more assured of, that, being grounded in the truth, we may be guarded against error, for certainty in religion is of great importance and advantage: Knowing, (1.) "That thou hast had good teachers. Consider of whom thou hast learned them; not of evil men and seducers, but good men, who had themselves experienced the power of the truths they taught thee, and been ready to suffer for them, and thereby would give the fullest evidence of their belief of these truths." (2.) "Knowing especially the firm foundation upon which thou hast built, namely, that of the scripture (Ti2 3:15): That from a child thou hast known the holy scriptures."

2.Those who would acquaint themselves with the things of God, and be assured of them, must know the holy scriptures, for these are the summary of divine revelation.

3.It is a great happiness to know the holy scriptures from our childhood; and children should betimes get the knowledge of the scriptures. The age of children is the learning age; and those who would get true learning must get it out of the scriptures.

4.The scriptures we are to know are the holy scriptures; they come from the holy God, were delivered by holy men, contain holy precepts, treat of holy things, and were designed to make us holy and to lead us in the way of holiness to happiness; being called the holy scriptures, they are by this distinguished from profane writings of all sorts, and from those that only treat morality, and common justice and honesty, but do not meddle with holiness. If we would know the holy scriptures, we must read and search them daily, as the noble Bereans did, Act 17:11. They must not lie by us neglected, and seldom or never looked into. Now here observe,

(1.)What is the excellency of the scripture. It is given by inspiration of God (Ti2 3:16), and therefore is his word. It is a divine revelation, which we may depend upon as infallibly true. The same Spirit that breathed reason into us breathes revelation among us: For the prophecy came not in old time by the will of man, but holy men spoke as they were moved or carried forth by the Holy Ghost, Pe2 1:21. The prophets and apostles did not speak from themselves, but what they received of the Lord that they delivered unto us. That the scripture was given by inspiration of God appears from the majesty of its style, - from the truth, purity, and sublimity, of the doctrines contained in it, - from the harmony of its several parts, - from its power and efficacy on the minds of multitudes that converse with it, - from the accomplishment of many prophecies relating to things beyond all human foresight, - and from the uncontrollable miracles that were wrought in proof of its divine original: God also bearing them witness, both with signs and wonders, and with divers miracles and gifts of the Holy Ghost, according to his own will, Heb 2:4.

(2.)What use it will be of to us.

[1.]It is able to make us wise to salvation; that is, it is a sure guide in our way to eternal life. Note, Those are wise indeed who are wise to salvation. The scriptures are able to make us truly wise, wise for our souls and another world. "To make thee wise to salvation through faith." Observe, The scriptures will make us wise to salvation, if they be mixed with faith, and not otherwise, Heb 4:2. For, if we do not believe their truth and goodness, they will do us no good.

[2.]It is profitable to us for all the purposes of the Christian life, for doctrine, for reproof, for correction, for instruction in righteousness. It answers all the ends of divine revelation. It instructs us in that which is true, reproves us for that which is amiss, directs us in that which is good. It is of use to all, for we all need to be instructed, corrected, and reproved: it is of special use to ministers, who are to give instruction, correction, and reproof; and whence can they fetch it better than from the scripture?

[3.]That the man of God may be perfect, Ti2 3:17. The Christian, the minister, is the man of God. That which finishes a man of God in this world is the scripture. By it we are thoroughly furnished for every good work. There is that in the scripture which suits every case. Whatever duty we have to do, whatever service is required from us, we may find enough in the scriptures to furnish us for it.

(3.)On the whole we here see,

[1.]That the scripture has various uses, and answers divers ends and purposes: It is profitable for doctrine, for reproof, for correction of all errors in judgment and practice, and for instruction in righteousness.

[2.]The scripture is a perfect rule of faith and practice, and was designed for the man of God, the minister as well as the Christian who is devoted to God, for it is profitable for doctrine, etc.

[3.]If we consult the scripture, which was given by inspiration of God, and follow its directions, we shall be made men of God, perfect, and thoroughly furnished to every good work.

[4.]There is no occasion for the writings of the philosopher, nor for rabbinical fables, nor popish legends, nor unwritten traditions, to make us perfect men of God, since the scripture answers all these ends and purposes. O that we may love our Bibles more, and keep closer to them than ever! and then shall we find the benefit and advantage designed thereby, and shall at last attain the happiness therein promised and assured to us.

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Historical interpretation

Seventeen Centuries of Reception

17 surviving comments on this verse. Each one is dated, so this reads as a timeline rather than a list.

17 quotes · AD 253–1963
Ante-NicenePost-NiceneEarly MedievalMedieval
20030040050060070080090010001100120013001400150016001700180019002000

Select a marker to jump to its quote. Markers stagger vertically where authors wrote within a few decades of each other.

When you flee Egypt, you come to these steep ascents of work and faith. You face a tower, a sea and waves. The way of life is not pursued without the waves of temptation. The apostle says, “All who wish to live piously in Christ will suffer persecution.” Job also, no less, declares, “Our life upon earth is a temptation.”
AD 373Athanasius of AlexandriaPost-NiceneSourceFESTAL LETTERS 9
In another place the apostle says, “And all those who will live godly lives in Christ Jesus will suffer persecution.” Then, to help prevent people from renouncing godliness when they are persecuted, he urges them to cling to the faith. “You, therefore, continue in the things you have learned and been assured of.” Just as brothers become strongly knit together when one helps another, so faith and godliness, coming from the same family, cohere together. A person who gives his attention to one of the two is strengthened by the other.
AD 407John ChrysostomPost-NiceneSourceHomily on Acts 24
"For they that wish," says the Apostle, "to live godly in Christ Jesus, shall suffer persecution." They that live godly are always undergoing persecution, if not from men, at any rate from evil spirits, which is a more grievous persecution. Yes, and it is in consequence, first and foremost, of ease and comfort, that those who are not vigilant undergo this.
"Yea, and all those that will live godly in Christ Jesus shall suffer persecution." But why, he says, should I speak only of myself? Each one that will live godly will be persecuted. Here he calls afflictions and sorrows, "persecutions," for it is not possible that a man pursuing the course of virtue should not be exposed to grief, tribulation, and temptations. For how can he escape it who is treading in the strait and narrow way, and who has heard, that "in the world ye shall have tribulation"? (John xvi. 33.) If Job in his time said, "The life of man upon earth is a state of trial" (Job vii. 1, Gr.); how much more was it so in those days?
AD 407John ChrysostomPost-NiceneSourceON LAZARUS AND THE RICH MAN 3
If the road is narrow and difficult, how can it be that “My yoke is easy and my burden is light”? He says difficult because of the nature of the trials but easy because of the willingness of the travelers. It is possible for even what is unendurable by nature to become light when we accept it with eagerness. Remember that the apostles who had been scourged returned rejoicing that they had been found worthy to be dishonored for the name of the Lord.
AD 430Augustine of HippoPost-NiceneSourceSERMONS 46.11
What sort of people, though, are those who, being afraid to offend the ones they are talking to, not only don’t prepare them for the trials that are looming ahead but even promise them a well-being in this world which God himself hasn’t promised to the world? He foretells distress upon distress coming upon the world right up to the end, and do you wish the Christian to be exempt from these distresses? Precisely because he’s Christian, he is going to suffer more in this world.
Persecution, therefore, will never be lacking. For, when our enemies from without leave off raging and there ensues a span of tranquillity—even of genuine tranquillity and great consolation at least to the weak—we are not without enemies within, the many whose scandalous lives wound the hearts of the devout.… So it is that those who want to live piously in Christ must suffer the spiritual persecution of these and other aberrations in thought and morals, even when they are free from physical violence and vexation.
AD 435John CassianPost-NiceneSourceCONFERENCES 23-24
Abba Germanus said: “Since you have given us the remedies for every illusion, and since the diabolical snares that used to trouble us have been disclosed to us by your teaching and by the Lord’s gift, we beseech you likewise to explain to us completely this phrase from the Gospel, “My yoke is easy and my burden is light.” For it seems quite contrary to the words of the prophet, which say, “On account of the words of your lips I have kept to hard ways.” Indeed, even the apostle says, “All who wish to live devoutly in Christ suffer persecution.” Whatever is hard and has reference to persecution, however, can be neither light nor easy.” Abba Abraham said, “We shall demonstrate by the easy proof of experience itself that the words of our Lord and Savior are most true, if we set out on the path of perfection in lawful manner and in accordance with the will of Christ.… For what can be heavy or hard to the person who has taken up Christ’s yoke with his whole mind, is established in true humility, reflects constantly upon the Lord’s suffering and rejoices in all the hardships that come upon him?”
AD 458Theodoret of CyrusPost-NiceneSourceLETTERS 109
Many are the devices secretly plotted against me and through me patched up against the faith of apostles. I am however comforted by the sufferings of the saints, prophets, apostles, martyrs and men famous in the churches in the word of grace and besides these by the promises of our God and Savior. For in the present life he has promised us nothing pleasant or delightful, but rather trouble, toil, and peril and attacks of enemies.
AD 461Leo the GreatPost-NiceneSourceLETTERS 167.1
I am amazed that your charity is so overcome with tribulation from scandals, no matter from what occasion they arise, that you say you desire to be freed from the labors of your bishopric and prefer to live in silence and leisure rather than continue handling those problems which were entrusted to you. But, as the Lord said, “Blessed is he that perseveres to the end.” From what will this blessed perseverance come if not from the virtue of patience? For, according to the teaching of the apostle, “All who want to live piously in Christ will suffer persecution.” Persecution is to be reckoned not only as that which is done against Christian piety by the sword or fire or by any torments whatever, for the ravages of persecution are also inflicted by differences of character, the perversity of the disobedient and the barbs of slanderous tongues.
AD 542Caesarius of ArlesPost-NiceneSourceSERMONS 215.3
Do not seek on the journey what is being kept for you in your fatherland. Because it is necessary for you to fight against the devil every day under the leadership of Christ, do not seek in the midst of battle the reward which is being saved for you in the kingdom. During the fight you ought not to look for what is being kept for you when victory has been attained. Rather pay attention to what the apostle says, “Anyone who wants to live a godly life in Christ can expect to be persecuted,” and again, “We must undergo many trials if we are to enter the reign of God.”
AD 542Caesarius of ArlesPost-NiceneSourceSERMONS 103.1
“All who want to live piously in Christ suffer persecution,” says the apostle. They are under attack from the enemy. For this reason, with Christ’s help, everyone who travels the journey of this life should be armed unceasingly and always stand in camp. So if you want to be constantly vigilant so that you may know you serve in the Lord’s camp, observe what the same apostle says, “No one serving as God’s soldier entangles himself in worldly affairs, that he may please him whose approval he has secured.”
AD 700Isaac of NinevehEarly MedievalSourceHOMILIES 72
And the blessed Mark the Monk has said, “Every virtue on being achieved is called a cross, when it fulfills the Spirit’s commandment.” That is why all those who wish in the fear of the Lord to live in Jesus Christ will suffer persecution.
AD 735BedeEarly MedievalSourceHomilies on the Gospels 2.22
Paul permeated the corpus of his writings, which is made up of fourteen letters, with the aroma of Christ alone, if I may speak of Christ in this way. Whatever you read there either reveals the hidden mysteries of the faith, or shows the results of good works, or promises the joys of the heavenly kingdom, or lays bare the tribulations he sustained in preaching these things, or relates the divine consolation he received in the midst of his tribulations or suggests by a general exhortation that all “those who wish to live a good life in Christ” will not lack persecutions.… He knew most clearly and foretold with an unrestrained voice that his being killed for the Lord’s sake was nothing else but a most acceptable and pure sacrificial offering made to the Lord. Therefore Paul too glorified God, as did the rest of the apostles, for they too loved Christ with a pure heart and took care of Christ’s sheep with a sincere intent.
AD 749John DamasceneEarly Medieval
As he remembered these things when he was younger, yet he was still well aware of it.
AD 990OecumeniusEarly MedievalSourceCOMMENTARY ON 2 TIMOTHY
And all who desire to live godly in Christ Jesus will be persecuted. But evil men and impostors will grow worse and worse, deceiving and being deceived.

And what am I saying about myself? For all who desire to live piously will be persecuted, Paul says, persecution not only from the idolaters but also tribulations and temptations. For the way of life is narrow and afflicted. (Matt. 7:14)

in Christ Jesus. For this alone is a godly life, the one in Christ Jesus.

will be persecuted. Such is the nature of things. Since the present life is not for the godly, but for the wicked. For no one lives in peace who wages war and shoots arrows.

will grow worse and worse. For to grow is split in the middle, both for the better or for the worse. Therefore, these will grow towards the worse. For by interpreting what worse is, Paul said that they themselves will be led into error and will get it wrong.
Which of the religions of the world gives to its followers the greatest happiness? While it lasts, the religion of worshiping oneself is the best. I have an elderly acquaintance of about eighty, who has lived a life of unbroken selfishness and self-admiration from the earliest years, and is, more or less, I regret to say, one of the happiest men I know. From the moral point of view it is very difficult! I am not approaching the question from that angle. As you perhaps know, I haven't always been a Christian. I didn't go to religion to make me happy. I always knew a bottle of port would do that. If you want a religion to make you feel really comfortable, I certainly don't recommend Christianity.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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