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G5521

χολή

cholḗ /khol-ay'/ Ask about this word
feminine of an equivalent perhaps akin to the same as 5514 (from the greenish hue)
"gall" or bile, i.e. (by analogy) poison or an anodyne (wormwood, poppy, etc.)
gall.

Word Study

In depth

A plain-language study of cholḗ — the range of meaning it carries, how Scripture actually uses it, and where it points. Written for readers who don’t know the original language.

Core Meaning & Semantic Range

The Greek word cholḗ, represented by G5521, refers to "gall" or bile. According to its base definition, it can denote poison or an anodyne substance like wormwood or poppy. This word appears 2 times across 2 unique verses in the Bible.

Biblical Occurrences & Contextual Analysis

The word G5521 is used both literally and figuratively in scripture. In a literal sense, it describes a substance offered to Jesus during the crucifixion, where soldiers gave him vinegar to drink mingled with gall Matthew 27:34. Figuratively, it is used to characterize a state of profound spiritual corruption, as when Peter perceives a person to be in the "gall of bitterness, and in the bond of iniquity" Acts 8:23.

Related Words & Concepts

Several related words help clarify the meaning of G5521 in its contexts:

  • G3690 óxos (vinegar): Defined as "vinegar, i.e. sour wine," this word is directly paired with gall in the drink offered to Jesus on the cross Matthew 27:34.
  • G4088 pikría (bitterness): Meaning "acridity (especially poison), literally or figuratively," this term is used with gall to describe a state of deep-seated sinfulness Acts 8:23.
  • G4886 sýndesmos (bond): This word, meaning "a joint tie, i.e. ligament, (figuratively) uniting principle, control," is used alongside gall to illustrate being trapped, specifically in "the bond of iniquity" Acts 8:23.

Theological Significance

The theological weight of G5521 is demonstrated in its two distinct applications.

  • Symbol of Suffering: The offering of gall G5521 mingled with vinegar G3690 to Jesus represents a moment of intense suffering and mockery during the crucifixion narrative Matthew 27:34.
  • Metaphor for Moral Corruption: In the book of Acts, gall is used metaphorically to diagnose a spiritual condition. Being "in the gall of bitterness" G4088 is equated with being held in "the bond" G4886 of "iniquity" G93 Acts 8:23.
  • Conscious Rejection: Jesus's refusal to drink G4095 the mixture of vinegar and gall signifies a conscious choice. The base definition of gall includes "anodyne," suggesting he rejected a substance that could have dulled his senses Matthew 27:34.

Summary

In summary, cholḗ G5521, though appearing only twice, carries significant weight. It functions both as a literal, bitter substance associated with the physical suffering of Christ, and as a powerful metaphor for the poisonous nature of sin and spiritual corruption. Its use in scripture highlights themes of suffering, rejection, and the deep-seated nature of iniquity.

How the KJV Renders It

Translation

Strong’s lists the renderings but not their weight. These are counted from the King James text of the tagged verses — the bar under each is how often the translators actually reached for it. Select one to filter the occurrences below.

Grammatical Forms

Morphology

In the Greek New Testament, this word appears as a noun across 2 occurrences, inflected in 2 grammatical forms — each row is one form, and the bar is how often it is that form.

  • Accusative Singular Feminine
  • Genitive Singular Feminine
Genitive
Possession or source — often "of".
Accusative
The direct object of the verb.
Singular
One.
Feminine
Feminine grammatical gender.

Related Words

Related

Other entries the study above points to — each one is drawn from a reference it makes. Follow the trail to see how the words connect.

Theographic Context

Context

The people, places, and span of history the verses containing this word touch on — drawn from the theographic tagging of Scripture. Select any name to isolate its verses in the occurrence list.

Biblical Distribution

Distribution

Appears in 2 verses across 2 of the 27 books. Most frequent in Matthew and Acts (1 verse each); never once in the other 25.

1
Matthew
1
Acts

Every Occurrence

Concordance

Every verse where the word is tagged in the King James text. Filter by book, by the English word the translators chose, or search within the verses.

Sources. Definition and numbering: James Strong, Exhaustive Concordance of the Bible (1890). Morphology: STEPBible / Tyndale House (CC BY). Verse tagging: the King James text keyed to Strong’s numbers. Every count on this page is computed from the tagged corpus, not estimated.