Found 4 Strong's definitions.
sometimes מַכְאוֹב; also (feminine Isaiah 53:3) מַכְאֹבָה; from כָּאַב; anguish or (figuratively) affliction; grief, pain, sorrow.
from חָלָה; malady, anxiety, calamity; disease, grief, (is) sick(-ness).
or עָווֹן; (2 Kings 7:9; Psalm 51:5 (אֲבַד)), from עָוָה; perversity, i.e. (moral) evil; fault, iniquity, mischeif, punishment (of iniquity), sin.
from יָגָה; affliction; grief, sorrow.
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