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Translation
King James Version
Then was the part of the hand sent from him; and this writing was written.
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KJV (with Strong's)
Then H116 was the part H6447 of the hand H3028 sent H7972 from H4481 him H6925; and this H1836 writing H3792 was written H7560.
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Complete Jewish Bible
This is why he sent the hand to write this inscription;
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Berean Standard Bible
Therefore He sent the hand that wrote the inscription.
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American Standard Version
Then was the part of the hand sent from before him, and this writing was inscribed.
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World English Bible Messianic
Then was the part of the hand sent from before him, and this writing was inscribed.
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Geneva Bible (1599)
Then was the palme of the hand sent from him, and hath written this writing.
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Young's Literal Translation
`Then from before Him sent is the extremity of the hand, and the writing is noted down;
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In the KJVVerse 21,899 of 31,102

Study This Verse

SUMMARY

Daniel 5:24 serves as the pivotal declaration within the dramatic narrative of Belshazzar's feast, explicitly confirming the divine origin of the mysterious handwriting on the palace wall. This verse reveals that the disembodied "part of the hand" was supernaturally "sent from him"—God Himself—to inscribe a message of impending judgment, thereby validating the terrifying omen and establishing the foundation for Daniel's subsequent interpretation and the swift downfall of the Babylonian Empire.

CONTEXT

  • Literary Context: Daniel 5:24 functions as the critical interpretive pivot point within the unfolding drama of Belshazzar's feast, detailed throughout Daniel 5. The narrative commences with King Belshazzar's audacious and sacrilegious act of profaning the sacred vessels taken from the Jerusalem temple during his drunken revelry (Daniel 5:1-4). This act of blatant defiance against the God of Israel immediately precipitates the terrifying appearance of the disembodied hand (Daniel 5:5). The king's profound terror and the subsequent failure of his wise men to decipher the mysterious writing (Daniel 5:6-9) create a narrative vacuum that only Daniel, empowered by divine wisdom, can fill. Verse 24, spoken by Daniel, serves as his authoritative preamble, unequivocally affirming the divine source of the phenomenon before he delivers the devastating interpretation of "Mene, Mene, Tekel, Upharsin" in Daniel 5:25-28. It masterfully underscores that the ensuing judgment is not arbitrary but a direct, intentional, and sovereign act of God.
  • Historical & Cultural Context: This momentous event transpires in Babylon during the twilight years of the Neo-Babylonian Empire, specifically on the fateful night of its conquest by the Medo-Persian forces in 539 BC. King Belshazzar, serving as co-regent with his father Nabonidus, hosts an extravagant feast, a customary display of wealth and power among ancient Near Eastern monarchs. However, his impious decision to utilize the sacred vessels plundered by Nebuchadnezzar from the Jerusalem Temple (2 Kings 25:13-17) transcends mere revelry; it constitutes an act of profound religious and political audacity. In the ancient world, the desecration of conquered deities' cultic objects was a potent symbolic assertion of one's own god's supremacy. Belshazzar's act was not merely impious but a direct challenge to Yahweh, the God of Israel, whose supreme power even Nebuchadnezzar had eventually acknowledged (Daniel 4:34-37). The sudden, miraculous appearance of the writing hand on the plastered wall of the palace (Daniel 5:5) would have been perceived as an unmistakable, terrifying omen, a direct divine intervention in a culture deeply attuned to omens and divine messages.
  • Key Themes: Daniel 5:24 profoundly contributes to several overarching themes woven throughout the book of Daniel. Firstly, it powerfully reiterates the theme of Divine Sovereignty over earthly kingdoms and their rulers, a foundational concept consistently emphasized throughout the book, as seen in passages like Daniel 2:21 and Daniel 4:17. The explicit statement that the hand was "sent from him" directly attributes the entire event to God's active, controlling, and sovereign hand in human history. Secondly, the verse starkly highlights the theme of Divine Judgment, particularly against pride, blasphemy, and open defiance of God's authority. Belshazzar's brazen profanation of the sacred vessels is met with immediate, supernatural condemnation, serving as a chilling warning against human arrogance, echoing the fate of his predecessor, Nebuchadnezzar, in Daniel 4. Finally, Daniel 5:24 underscores the theme of Divine Revelation and Communication. The mysterious writing is a direct, albeit initially incomprehensible, message from God, demonstrating His ability and willingness to communicate His will and decrees to humanity, especially concerning matters of judgment and the unfolding of His redemptive plan.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • part (Aramaic, paç', H6447): This Aramaic term, derived from a root meaning "to spread out," specifically refers to the "palm" of the hand. Its usage here emphasizes that only a portion of the hand, the open palm, was visibly active in the act of writing. This partial manifestation underscores the supernatural and mysterious nature of the event, suggesting a divine, rather than fully corporeal, presence. It deliberately focuses attention solely on the act of inscription, rendering the source of the message all the more awe-inspiring and terrifying.
  • hand (Aramaic, yad', H3028): Corresponding to the Hebrew yad, this term denotes not merely the physical appendage but also carries connotations of power, means, and direction. In this profound context, the "hand" serves as a powerful metonymy for the direct agency and omnipotence of God. It emphasizes that the writing on the wall was not a random or coincidental occurrence but a deliberate, powerful act of God's will and authority, directly intervening in human affairs to execute a preordained judgment.
  • written (Aramaic, rᵉsham', H7560): This Aramaic verb, meaning "to record" or "to sign," appears in its passive form ("was written"). This grammatical construction profoundly underscores that the inscription was not a human act but an indelible mark made by a higher, divine power. The very act of writing inherently denotes permanence, authority, and an unchangeable decree. The message, once inscribed, became an undeniable and unalterable divine pronouncement, irrevocably sealing Belshazzar's fate.

Verse Breakdown

  • "Then was the part of the hand sent from him;": This clause dramatically unveils the divine origin and supernatural nature of the terrifying writing phenomenon. The "part of the hand" refers to the mysterious, disembodied hand that materialized to write. The crucial phrase "sent from him" explicitly attributes the action to God, whose divine judgment is the overarching theme of the chapter and Daniel's subsequent interpretation. This establishes unequivocally that the terrifying event was not an illusion, a trick, or a random occurrence, but a direct, intentional act of divine intervention, signaling a momentous and divinely ordained message.
  • "and this writing was written.": This second clause confirms the immediate and undeniable result of the divine action: a message was inscribed on the wall. The inherent repetition in "this writing was written" (where the noun "writing" is derived from the verb "to write") serves to powerfully emphasize the certainty, reality, and finality of the inscription. It underscores that a definitive, authoritative, and unalterable message from God had been visibly placed on the wall, awaiting interpretation and execution, leaving absolutely no doubt about its authenticity or its ultimate authority.

Literary Devices

Daniel 5:24 masterfully employs several potent literary devices to heighten the drama and theological impact of the narrative. The appearance of the disembodied hand is a powerful instance of Theophany, a manifestation of God's presence and active involvement in human affairs, albeit indirect and terrifying. The "part of the hand" itself functions as profound Symbolism, representing divine power, righteous judgment, and the direct, undeniable intervention of God's sovereign will. It stands as a vivid visual metaphor for God's ultimate control over earthly rulers and kingdoms, literally inscribing their destiny. The entire scene, culminating in this verse, is steeped in Dramatic Irony, as Belshazzar and his court remain tragically oblivious to the true significance of the sacred vessels and the omnipotent God they are defiantly challenging, while the reader (and Daniel) possess a clear understanding of the profound implications of God's direct and terrifying response. The stark contrast between the king's drunken revelry and the sudden, terrifying divine inscription creates a powerful sense of Foreshadowing, signaling the imminent and unavoidable judgment that will be fully revealed in Daniel's devastating interpretation.

THEOLOGICAL AND THEMATIC CONNECTIONS

Daniel 5:24 stands as a profound theological statement on God's active sovereignty and His righteous judgment over human arrogance and rebellion. It asserts unequivocally that no earthly power, no matter how mighty, defiant, or self-assured, is beyond the direct reach of divine oversight and ultimate accountability. The direct intervention of God to inscribe a message of doom underscores that ultimate authority resides not in transient kings or fleeting empires, but solely in the Most High God, who "removes kings and sets up kings" (Daniel 2:21). This dramatic event serves as a powerful and enduring reminder that God holds all of humanity accountable for their actions, particularly those who profane His holiness, disregard His commands, or exalt themselves against Him. It reveals a God who is not distant or detached but intimately involved in the course of history, meticulously bringing about His eternal purposes through both miraculous signs and the unfolding of His divine plan.

REFLECTION AND APPLICATION

Daniel 5:24 serves as a timeless and potent warning against the perils of pride, blasphemy, and the dangerous illusion of human autonomy. Belshazzar's catastrophic downfall, directly precipitated by his defiant profanation of sacred objects and his disregard for divine warnings, powerfully reminds us that God is not mocked and that His absolute holiness demands profound reverence. In our contemporary lives, this verse compels us to humbly examine where we might be exhibiting arrogance, whether through our casual disregard for spiritual truths, our careless misuse of God-given resources and talents, or our open defiance of moral and ethical boundaries. It challenges us to live with a constant, reverent awareness of God's absolute sovereignty and His ultimate authority over all aspects of life. Just as the writing on the wall was an undeniable sign of impending judgment for Belshazzar, we are called to discern the "signs of the times" and to live in humility, obedience, and spiritual discernment, recognizing that every action, whether public or private, carries profound spiritual implications and is not hidden from the One who holds the scales of justice.

Questions for Reflection

  • In what specific areas of my life might I be acting with a spirit of pride or defiance towards God's revealed will or His holy standards?
  • How does the swift and public judgment on Belshazzar encourage me to cultivate greater humility and a deeper reverence for God in my daily life?
  • What "sacred vessels" or blessings—whether gifts, resources, or relationships—in my life might I be profaning or taking for granted, rather than stewarding them for God's glory and purposes?

FAQ

Was the hand that wrote on the wall a literal human hand?

Answer: The text describes it as "the part of the hand," implying a partial, disembodied manifestation rather than a full human hand. The Aramaic word for "part" (H6447, paç) specifically refers to the palm. This supernatural appearance profoundly emphasizes its divine origin and miraculous nature, distinguishing it from an ordinary human hand. It was a direct, visible sign of God's intervention, not the action of a physical human agent.

Why was the writing unintelligible to Belshazzar's wise men?

Answer: The text does not explicitly state the precise reason why the wise men could not read or interpret the writing, but several possibilities exist. It may have been written in an ancient or obscure script (such as Old Hebrew or Phoenician), a cryptographic code, or perhaps the letters appeared but their meaning or arrangement was divinely obscured from those without spiritual discernment. The most compelling reason, however, is likely not merely linguistic but spiritual: God had deliberately withheld the understanding from them because they lacked the divine wisdom necessary to comprehend His sacred message, a wisdom uniquely possessed by Daniel (Daniel 5:11-12). Their inability highlighted their spiritual blindness and underscored God's exclusive revelation through His chosen prophet.

CHRIST-CENTERED FULFILLMENT

Daniel 5:24, with its vivid depiction of divine judgment against a defiant king and an unholy kingdom, finds profound Christ-centered fulfillment in the ultimate judgment and absolute sovereignty of God revealed through Jesus Christ. Just as a mysterious hand wrote the inescapable fate of Babylon, so too does the "hand" of God, supremely embodied in Christ, hold the ultimate authority over all nations, all history, and all individual destinies. Jesus, as the Lamb of God who takes away the sin of the world, is also the divinely appointed judge of the living and the dead. Belshazzar's brazen profanation of the temple vessels tragically foreshadows humanity's far greater sin of rejecting and crucifying the very Son of God, who is the true Temple and the dwelling place of God among us (John 2:19-21). The swift and certain judgment upon Babylon points forward to the final, universal judgment when every knee will bow and every tongue will confess that Jesus Christ is Lord, to the glory of God the Father. The terrifying message of "Mene, Mene, Tekel, Upharsin" ("numbered, weighed, divided") finds its ultimate echo in Christ's urgent call for repentance and His gracious promise of salvation for all who turn from their pride and trust in Him, for apart from Him, all are "weighed in the balances and found wanting" (Daniel 5:27). Yet, for those who believe and embrace His grace, there is no condemnation, but eternal life through the One whose "hand" was pierced for our salvation, offering a new covenant of grace and forgiveness (John 3:17-18).

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Commentary on Daniel 5 verses 10–29

I. II. Main points1. 2. Sub-points(1.) (2.) Details

Here is, I. The information given to the king, by the queen-mother, concerning Daniel, how fit he was to be consulted in this difficult case. It is supposed that this queen was the widow of Evil-Merodach, and was that famous Nitocris whom Herodotus mentions as a woman of extraordinary prudence. She was not present at the feast, as the king's wives and concubines were (Dan 5:2); it was not agreeable to her age and gravity to keep a merry night. But, tidings of the fright which the king and his lords were put into being brought to her apartment, she came herself to the banqueting-house, to recommend to the king a physician for his melancholy. She entreated him not to be discouraged by the insufficiency of his wise men to solve this riddle, for that there was a man in his kingdom that had more than once helped his grandfather at such a dead lift, and, no doubt, could help him, Dan 5:11, Dan 5:12. She could not undertake to read the writing herself, but directed him to one that could; let Daniel be called now, who should have been called first. Now observe, 1. The high character she gives of Daniel: He is a man in whom is the spirit of the holy gods, who has something in him more than human, not only the spirit of a man, which, in all, is the candle of the Lord, but a divine spirit. According to the language of her country and religion, she could not give a higher encomium of any man; she speaks honourably of him as a man that had, (1.) An admirably good head: Light, and understanding, and wisdom, like the wisdom of the gods, were found in him. Such an insight had he into things secret, and such a foresight of things to come, that it was evident he was divinely inspired; he had knowledge and understanding beyond all the other wise men for interpreting dreams, explaining enigmas or hard sentences, untying knots, and resolving doubts. Solomon had a wonderful sagacity of this kind; but it should seem that in these things Daniel had more of an immediate divine direction. Behold, a greater than Solomon himself is here. Yet what was the wisdom of them both compared with the treasures of wisdom hidden in Christ? (2.) He had an admirably good heart: An excellent spirit was found in him, which was a great ornament to his wisdom and knowledge, and qualified him to receive that gift; for God gives to a man that is good in his sight wisdom, and knowledge, and joy. He was of a humble, holy, heavenly spirit, had a devout and gracious spirit, a spirit of zeal for the glory of God and the good of men. This was indeed an excellent spirit. 2. The account she gives of the respect that Nebuchadnezzar had for him; he was much in his favour, and was preferred by him: "The king thy father" (that is, thy grandfather, but even to many generations Nebuchadnezzar might well be called the father of that royal family, for he it was that raised it to such a pitch of grandeur), "the king, I say, thy father, made him master of the magicians." Perhaps Belshazzar had sometimes, in his pride, spoken slightly of Nebuchadnezzar, and his politics, and the methods of his government, and the ministers he employed, and thought himself wiser than he; and therefore his mother harps upon that. "The king, I say, thy father, to whose good management all thou hast owing, he pronounced him chief of, and gave him dominion over, all the wise men of Babylon, and named him Belteshazzar, according to the name of his god, thinking thereby to put honour upon him;" but Daniel, by constantly making use of his Jewish name himself (which he resolved to keep, in token of his faithful adherence to his religion), had worn out that name; only the queen-dowager remembered it, otherwise he was generally called Daniel. Note, It is a very good office to revive the remembrance of the good services of worthy men, who are themselves modest, and willing that they should be forgotten. 3. The motion she makes concerning him: Let Daniel be called, and he will show the interpretation. By this it appears that Daniel was now forgotten at court. Belshazzar was a stranger to him, knew not that he had such a jewel in his kingdom. With the new king there came in a new ministry, and the old one was laid aside. Note, There are a great many valuable men, and such as might be made very useful, that lie long buried in obscurity, and some that have done eminent services that live to be overlooked and taken no notice of; but, whatever men are, God is not unrighteous to forget the services done to his kingdom. Daniel, being turned out of his place, lived privately, and sought not any opportunity to come into notice again; yet he lived near the court and within call, though Babylon was now besieged, that he might be ready, if there were occasion, to do any good office, by what interest he had among the great ones, for the children of his people. But Providence so ordered it that now, just at the fall of that monarchy, he should by the queen's means be brought to court again, that he might lie there ready for preferment in the ensuing government. Thus do the righteous shine forth out of obscurity, and before honour is humility.

II. The introducing of Daniel to the king, and his request to him to read and expound the writing. Daniel was brought in before the king, Dan 5:13. He was now nearly ninety years of age, so that his years, and honours, and former preferments, might have entitled him to a free admission into the king's presence; yet he was willing to be conducted in, as a stranger, by the master of the ceremonies. Note, 1. The king asks, with an air of haughtiness: Art thou that Daniel who art of the children of the captivity? Being a Jew, and a captive, he was loth to be beholden to him if he could help it. 2. He tells him what an encomium he had heard of him (Dan 5:14), that the spirit of the gods was in him; and he had sent for him to try whether he deserved so high a character or no. 3. He acknowledges that all the wise men of Babylon were baffled; they could not read this writing, nor show the interpretation, Dan 5:16. But, 4. He promises him the same rewards that he had promised them if he would do it, Dan 5:16. It was strange that the magicians, when now, and in Nebuchadnezzar's time, once and again, they were nonplussed, did not attempt something to save their credit; if they had with a good assurance said, "This is the meaning of such a dream, such a writing," who could disprove them? But God so ordered it that they had nothing at all to say, as, when Christ was born, the heathen oracles were struck dumb.

III. The interpretation which Daniel gave of these mystic characters, which was so far from easing the king of his fears that we may suppose it increased them rather. Daniel was now in years, and Belshazzar was young; and therefore he seems to take a greater liberty of dealing plainly and roundly with him than he had done upon the like occasions with Nebuchadnezzar. In reproving any man, especially great men, there is need of wisdom to consider all circumstances; for they are the reproofs of instruction that are the way of life. In Daniel's discourse here,

1.He undertakes to read the writing which gave them this alarm, and to show them the interpretation of it, Dan 5:17. He slights the offer he made him of rewards, is not pleased that it was mentioned, for he is not one of those that divine for money; what gratuities Nebuchadnezzar gave him afterwards he gladly accepted, but he scorned to bargain for them, or to read the writing to the king for and in consideration of such and such honours promised him. No: "Let thy gifts be to thyself, for they will not be long thine, and give thy fee to another, to any of the wise men whom thou wouldst have most wished to earn it; I value it not." Daniel sees his kingdom now at its last gasp, and therefore looks with contempt upon his gifts and rewards. And thus should we despise all the gifts and rewards that this world can give did we see, as we may by faith, its final period hastening on. Let it give its perishing gifts to another; there are better gifts which we have our eyes and hearts upon; but let us do our duty in the world, do it all the real service we can, read God's writing to it in a profession of religion, and by an agreeable conversation make known the interpretation of it, and then trust God for his gifts, his rewards, in comparison with which all the world can give is mere trash and trifles.

2.He largely recounts to the king God's dealings with his father Nebuchadnezzar, which were intended for instruction and warning to him, Dan 5:18, Dan 5:21. This is not intended for a flourish or an amusement, but is a necessary preliminary to the interpretation of the writing. Note, That we may understand aright what God is doing with us, it is of use to us to review what he has done with others.

(1.)He describes the great dignity and power to which the divine Providence had advanced Nebuchadnezzar, Dan 5:18, Dan 5:19. He had a kingdom, and majesty, and glory, and honour, for aught we know, above what any heathen prince ever had before him; he thought that he got his glory by his own extraordinary conduct and courage, and ascribed his successes to a projecting active genius of his own; but Daniel tells him who now enjoyed what he had laboured for that it was the most high God, the God of gods and Lord of kings (as Nebuchadnezzar himself had called him), that gave him that kingdom, that vast dominion, that majesty wherewith he presided in the affairs of it, and that glory and honour which by his prosperous management he acquired. Note, Whatever degree of outward prosperity any arrive at, they must own that it is of God's giving, not their own getting. Let it never be said, My might, and the power of my hand, have gotten me this wealth, this preferment; but let it always be remembered that it is God that gives men power to get wealth, and gives success to their endeavours. Now the power which God gave to Nebuchadnezzar is here described to be very great in respect both of ability and of authority. [1.] His ability was so strong that it was irresistible; such was the majesty that God gave him, so numerous were the forces he had at command, and such an admirable dexterity he had at commanding them, that, which way soever his sword turned, it prospered. He could captivate and subdue nations by threatening them, without striking a stroke, for all people trembled and feared before him, and would compound with him for their lives upon any terms. See what force is, and what the fear of it does. It is that by which the brutal part of the world, even of the world of mankind, both governs and is governed. [2.] His authority was so absolute that it was uncontrollable. The power which was allowed him, which descended upon him, or which, at least, he assumed, was without contradiction, was absolute and despotic, none shared with him either in the legislative or in the executive part of it. In dispensing punishments he condemned or acquitted at pleasure: Whom he would he slew, and whom he would he saved alive, though both were equally innocent or equally guilty. The jus vitae et necis - the power of life and death was entirely in his hand. In dispensing rewards he granted or denied preferment at pleasure: Whom he would he set up, and whom he would he put down, merely for a humour, and without giving a reason so much as to himself; but it is all ex mero motu - of his own good pleasure, and stat pro ratione voluntas - his will stands for a reason. Such was the constitution of the eastern monarchies, such the manner of their kings.

(2.)He sets before him the sins which Nebuchadnezzar had been guilty of, whereby he had provoked God against him. [1.] He behaved insultingly towards those that were under him, and grew tyrannical and oppressive. The description given of his power intimates his abuse of his power, and that he was directed in what he did by humour and passion, not by reason and equity; so that he often condemned the innocent and acquitted the guilty, both which are an abomination to the Lord. He deposed men of merit and preferred unworthy men, to the great detriment of the public, and for this he was accountable to the most high God, that gave him his power. Note, It is a very hard and rare thing for men to have an absolute arbitrary power, and not to make an ill use of it. Camden has a distich of Giraldus, wherein he speaks of it as a rare instance, concerning our king Henry II of England, that never any man had so much power and did so little hurt with it.

Glorior hoc uno, quod nunquam vidimus unum,

Nec potuisse magis, nec nocuisse minus -

Of him I can say, exulting, that with the same power

to do harm no one was ever more inoffensive.

But that was not all. [2.] He behaved insolently towards the God above him, and grew proud and haughty (Dan 5:20): His heart was lifted up, and there his sin and ruin began; his mind was hardened in pride, hardened against the commands of God and his judgments; he was willful and obstinate, and neither the word of God nor his rod made any lasting impression upon him. Note, Pride is a sin that hardens the heart in all other sin and renders the means of repentance and reformation ineffectual.

(3.)He reminds him of the judgments of God that were brought upon him for his pride and obstinacy, how he was deprived of his reason, and so deposed from his kingly throne (Dan 5:20), driven from among men, to dwell with the wild asses, Dan 5:21. He that would not govern his subjects by rules of reason had not reason sufficient for the government himself. Note, Justly does God deprive men of their reason when they become unreasonable and will not use it, and of their power when they become oppressive and use it ill. He continued like a brute till he knew and embraced that first principle of religion, That the most high God rules. And it is rather by religion than reason that man is distinguished from, and dignified above, the beasts; and it is more his honour to be a subject to the supreme Creator than to be lord of the inferior creatures. Note, Kings must know, or shall be made to know, that the most high God rules in their kingdoms (that is an imperium in imperio - an empire within an empire, not to be excepted against), and that he appoints over them whomsoever he will. As he makes heirs, so he makes princes.

3.In God's name, he exhibits articles of impeachment against Belshazzar. Before he reads him his doom, from the hand-writing on the wall, he shows him his crime, that God may be justified when he speaks, and clear when he judges. Now that which he lays to his charge is, (1.) That he had not taken warning by the judgments of God upon his father (Dan 5:22): Thou his son, O Belshazzar! hast not humbled thy heart, though thou knewest all this. Note, It is a great offence to God if our hearts be not humbled before him to comply both with his precepts and with his providences, humbled by repentance, obedience, and patience; nay, he expects from the greatest of men that their hearts should be humbled before him, by an acknowledgment that, great as they are, to him they are accountable. And it is a great aggravation of the unhumbledness of our hearts when we know enough to humble them but do not consider and improve it, particularly when we know how others have been broken that would not bend, how others have fallen that would not stoop, and yet we continue stiff and inflexible. It makes the sin of children the more heinous if they tread in the steps of their parents' wickedness, though they have seen how dearly it has cost them, and how pernicious the consequences of it have been. Do we know this, do we know all this, and yet are we not humbled? (2.) That he had affronted God more impudently than Nebuchadnezzar himself had done, witness the revels of this very night, in the midst of which he was seized with this horror (Dan 5:23): "Thou hast lifted up thyself against the Lord of heaven, hast swelled with rage against him, and taken up arms against his crown and dignity, in this particular instance, that thou hast profaned the vessels of his house, and made the utensils of his sanctuary instruments of thy iniquity, and, in an actual designed contempt of him, hast praised the gods of silver and gold, which see not, nor hear, nor know anything, as if they were to be preferred before the God that sees, and hears, and knows every thing." Sinners that are resolved to go on in sin are well enough pleased with gods that neither see, nor hear, nor know, for then they may sin securely; but they will find, to their confusion, that though those are the gods they choose those are not the gods they must be judged by, but one to whom all things are naked and open. (3.) That he had not answered the end of his creation and maintenance: The God in whose hand thy breath is, and whose are all thy ways, hast thou not glorified. This is a general charge, which stands good against us all; let us consider how we shall answer it. Observe, [1.] Our dependence upon God as our creator, preserver, benefactor, owner, and ruler; not only from his hand our breath was at first, but in his hand our breath is still; it is he that holds our souls in life, and, if he take away our breath, we die. Our times being in his hand, so is our breath, by which our times are measured. In him we live, and move, and have our being; we live by him, live upon him, and cannot live without him. The way of man is not in himself, not at his own command, at his own disposal, but his are all our ways; for our hearts are in his hand, and so are the hearts of all men, even of kings, who seem to act most as free-agents. [2.] Our duty to God, in consideration of this dependence; we ought to glorify him, to devote ourselves to his honour and employ ourselves in his service, to make it our care to please him and our business to praise him. [3.] Our default in this duty, notwithstanding that dependence; we have not done it; for we have all sinned, and come short of the glory of God. This is the indictment against Belshazzar; there needs no proof, it is made good by the notorious evidence of the fact, and his own conscience cannot but plead guilty to it. And therefore,

4.He now proceeds to read the sentence, as he found it written upon the wall: "Then" (says Daniel) "when thou hast come to such a height of impiety as thus to trample upon the most sacred things, then when thou wast in the midst of thy sacrilegious idolatrous feast, then was the part of the hand, the writing fingers, sent from him, from that God whom thou didst so daringly affront, and who had borne so long with thee, but would bear no longer; he sent them, and this writing, thou now seest, was written, Dan 5:24. It is he that now writes bitter things against thee, and makes thee to possess thy iniquities," Job 13:26. Note, As the sin of sinners is written in the book of God's omniscience, so the doom of sinners is written in the book of God's law; and the day is coming when those books shall be opened, and they shall be judged by them. Now the writing was, Mene, Mene, Tekel, Upharsin, Dan 5:25. It is well that we have an authentic exposition of these words annexed, else we could make little of them, so concise are they; the signification of them is, He has numbered, he has weighed, and they divide. The Chaldean wise men, because they knew not that there is but one God only, could not understand who this He should be, and for that reason (some think) the writing puzzled them. (1.) Mene; that is repeated, for the thing is certain - Mene, mene; that signifies, both in Hebrew and Chaldee, He has numbered and finished, which Daniel explains thus (Dan 5:26): "God has numbered thy kingdom, the years and days of the continuance of it; these were numbered in the counsel of God, and now they are finished; the term has expired for and during which thou wast to hold it, and now it must be surrendered. Here is an end of thy kingdom." (2.) Tekel; that signifies, in Chaldee, Thou art weighed, and, in Hebrew, Thou art too light. So Dr. Lightfoot. For this king and his actions are weighed in the just and unerring balances of divine equity. God does as perfectly know his true character as the goldsmith knows the weight of that which he has weighed in the nicest scales. God does not give judgment against him till he has first pondered his actions, and considered the merits of his case. "But thou art found wanting, unworthy to have such a trust lodged in thee, a vain, light, empty man, a man of no weight or consideration." (3.) Upharsin, which should be rendered, and Pharsin, or Peres. Parsin, in Hebrew, signifies the Persians; Paresin, in Chaldee, signifies dividing; Daniel puts both together (Dan 5:28): "Thy kingdom is divided, is rent from thee, and given to the Medes and Persians, as a prey to be divided among them." Now this may, without any force, be applied to the doom of sinners. Mene, Tekel, Peres, may easily be made to signify death, judgment, and hell. At death, the sinner's days are numbered and finished; after death the judgment, when he will be weighed in the balance and found wanting; and after judgment the sinner will be cut asunder, and given as a prey to the devil and his angels. Daniel does not here give Belshazzar such advice and encouragement to repent as he had given Nebuchadnezzar, because he saw the decree had gone forth and he would not be allowed any space to repent.

One would have thought that Belshazzar would be exasperated against Daniel, and, seeing his own case desperate, would be in a rage against him. But he was so far convicted by his own conscience of the reasonableness of all he said that he objected nothing against it; but, on the contrary, gave Daniel the reward he promised him, put on him the scarlet gown and the gold chain, and proclaimed him the third ruler in the kingdom (Dan 5:29), because he would be as good as his word, and because it was not Daniel's fault if the exposition of the hand-writing was not such as he desired. Note, Many show great respect to God's prophets who yet have no regard to his word. Daniel did not value these titles and ensigns of honour, yet would not refuse them, because they were tokens of his prince's good-will: but we have reason to think that he received them with a smile, foreseeing how soon they would all wither with him that bestowed them. They were like Jonah's gourd, which came up in a night and perished in a night, and therefore it was folly for him to be exceedingly glad of them.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 10–29. Public domain.
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Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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