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Translation
King James Version
But woe unto them that are with child, and to them that give suck, in those days! for there shall be great distress in the land, and wrath upon this people.
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KJV (with Strong's)
But G1161 woe G3759 unto G1722 them that are with child G1064 G2192, and G2532 to them that give suck G2337, in G1722 those G1565 days G2250! for G1063 there shall be G2071 great G3173 distress G318 in G1909 the land G1093, and G2532 wrath G3709 upon G1722 this G5129 people G2992.
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Complete Jewish Bible
What a terrible time it will be for pregnant women and nursing mothers! For there will be great distress in the Land and judgment on the people.
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Berean Standard Bible
How miserable those days will be for pregnant and nursing mothers! For there will be great distress upon the land and wrath against this people.
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American Standard Version
Woe unto them that are with child and to them that give suck in those days! for there shall be great distress upon the land, and wrath unto this people.
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World English Bible Messianic
Woe to those who are pregnant and to those who nurse infants in those days! For there will be great distress in the land, and wrath to this people.
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Geneva Bible (1599)
But woe be to them that be with childe, and to them that giue sucke in those dayes: for there shalbe great distresse in this land, and wrath ouer this people.
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Young's Literal Translation
`And woe to those with child, and to those giving suck, in those days; for there shall be great distress on the land, and wrath on this people;
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In the KJVVerse 25,850 of 31,102

Study This Verse

SUMMARY

Luke 21:23 delivers a solemn and compassionate warning from Jesus Christ concerning the unparalleled suffering that would accompany the impending destruction of Jerusalem. This poignant declaration, part of His Olivet Discourse, expresses profound sorrow for the most vulnerable—pregnant and nursing women—who would face unimaginable hardship during this period of intense distress and divine judgment upon the Jewish people. It underscores the severity of the coming tribulation, emphasizing both its human cost and its theological significance as a consequence of rejecting God's redemptive plan.

CONTEXT

  • Literary Context: This verse is a critical component of Jesus' Olivet Discourse, recorded in Luke 21 (and parallel accounts in Matthew 24 and Mark 13). Following His prophecy regarding the complete destruction of the Temple in Luke 21:6, Jesus provides a series of signs and warnings about the "days of vengeance" (Luke 21:22). Specifically, Luke 21:20-21 instructs His followers to flee Jerusalem when they see it surrounded by armies, indicating the immediate precursor to the events described in verse 23. The "woe" pronounced here is not a curse but a lament, highlighting the extreme distress that would befall those unable to escape the city's siege.
  • Historical & Cultural Context: The primary historical fulfillment of this prophecy occurred during the Roman siege and destruction of Jerusalem in 70 AD. Led by General Titus, the Roman legions encircled the city, leading to a horrific period of famine, disease, and internal strife among the Jewish factions trapped within its walls. The cultural context of a siege meant that food and water would become scarce, sanitation would collapse, and escape would be virtually impossible for many. For pregnant women and those nursing infants, the physical demands of flight, the inability to find sustenance, and the heightened vulnerability to violence would have been catastrophic. Contemporary historical accounts, particularly those of Josephus in "The Jewish War," corroborate the extreme suffering, cannibalism, and immense loss of life during this period, making Jesus' warning profoundly accurate and compassionate.
  • Key Themes: Luke 21:23 contributes significantly to several key themes within the broader Olivet Discourse and Luke's Gospel. Firstly, it underscores the theme of Divine Judgment, demonstrating that the rejection of God's Messiah and the continued rebellion of the Jewish nation would incur severe consequences, culminating in the "wrath upon this people." Secondly, it highlights Prophetic Fulfillment, showcasing Jesus' divine foresight and the certainty of His words, which were meticulously fulfilled in 70 AD. Thirdly, it emphasizes Compassion Amidst Calamity, as Jesus' "woe" is not an expression of anger but of deep sorrow and empathy for the most vulnerable victims of the impending disaster. Finally, it serves as a call to Spiritual Vigilance and Preparedness, as the broader discourse encourages believers to discern the times and prepare for both immediate tribulations and the ultimate return of Christ, as seen in Luke 21:36.

EXPOSITION AND ANALYSIS

Key Word Analysis

  • Woe (Greek, ouaí', G3759): This is a primary exclamation of grief, sorrow, or lament. In this context, it is not merely a curse or an expression of anger, but a profound declaration of pity and deep regret for the immense suffering that is about to befall those in such a vulnerable state. It conveys the heavy heart of Jesus as He foresees the coming catastrophe.
  • Distress (Greek, anánkē', G318): Derived from a word implying constraint or necessity, anánkē refers to severe tribulation, compulsion, or overwhelming hardship. It emphasizes the unavoidable and intense nature of the suffering that would characterize the siege of Jerusalem, a period of inescapable and dire circumstances.
  • Wrath (Greek, orgḗ', G3709): This term, stemming from a word meaning "desire" or "excitement of the mind," denotes violent passion, indignation, or righteous judgment. In this verse, it specifically refers to divine indignation and the just recompense from God upon "this people" (the Jewish nation) for their rejection of His covenant and, ultimately, His Son. It signifies that the suffering is not random but a consequence of divine justice.

Verse Breakdown

  • "But woe unto them that are with child, and to them that give suck, in those days!": Jesus expresses profound sorrow and pity for pregnant women and nursing mothers. The phrase "in those days" refers specifically to the period of the Roman siege of Jerusalem in 70 AD, a time of extreme hardship, famine, and violence. These women, physically burdened and responsible for infants, would be uniquely disadvantaged and vulnerable, making escape or survival exceedingly difficult. Jesus' lament highlights the immense human cost of the impending catastrophe.
  • "for there shall be great distress in the land, and wrath upon this people.": This clause provides the reason for the "woe." The "great distress" signifies an unparalleled period of tribulation, characterized by famine, disease, and violence, as historically documented during the siege. The phrase "wrath upon this people" indicates that this suffering is not merely a random historical event but a consequence of divine judgment. This judgment fell upon the Jewish nation for its persistent rejection of God's covenant and ultimately, the Messiah, culminating in the destruction of their capital and Temple.

Literary Devices

Luke 21:23 employs several powerful literary devices to convey its message. The most prominent is Pathos, as Jesus' "woe" evokes deep pity and sorrow for the plight of the most vulnerable—pregnant and nursing women—during the impending catastrophe. This specific mention amplifies the emotional weight and horror of the forecasted events, making the suffering tangible and relatable. The verse also functions as a clear Prophecy, a direct foretelling of future events that would be fulfilled with chilling accuracy in 70 AD. Furthermore, the phrase "great distress" can be seen as a form of Hyperbole, emphasizing the extreme and unprecedented nature of the suffering, although historical accounts suggest it was hardly an overstatement given the horrors of the siege. The stark contrast between Jesus' compassionate lament and the severity of the "wrath" also creates a powerful Juxtaposition, highlighting both divine justice and divine mercy.

THEOLOGICAL AND THEMATIC CONNECTIONS

Luke 21:23 profoundly connects to the broader biblical narrative of divine judgment and the consequences of rejecting God's truth. While specifically foretelling the destruction of Jerusalem in 70 AD, it serves as a powerful reminder that God is sovereign over history and that His warnings are not to be taken lightly. The "wrath upon this people" underscores the concept of corporate judgment for national apostasy and the rejection of the Messiah, echoing Old Testament prophecies of Israel's covenant unfaithfulness. Yet, Jesus' lament also reveals God's deep compassion, even in judgment, for the suffering of humanity. The verse thus bridges themes of divine justice, prophetic fulfillment, and the enduring reality of human suffering in a fallen world, pointing to the ultimate need for repentance and reliance on God's redemptive plan.

REFLECTION AND APPLICATION

Luke 21:23, while rooted in a specific historical prophecy, offers timeless principles for reflection and application in the life of a believer. It powerfully reminds us of the gravity of God's warnings and the reality of consequences for rejecting His truth. Just as Jerusalem faced judgment for its spiritual blindness and rebellion, so too are there spiritual and temporal repercussions for individuals and societies that turn away from God. This verse calls us to a posture of humility and repentance, recognizing that our ultimate safety and peace are found not in earthly security but in faithful obedience to Christ. Furthermore, Jesus' compassionate lament for the vulnerable during a time of immense suffering challenges us to cultivate a profound empathy for those who suffer, especially in times of crisis. It compels us to be agents of compassion and practical aid, mirroring Christ's own heart for the distressed. Finally, the broader context of the Olivet Discourse, which includes this verse, serves as a call to spiritual vigilance, urging us to live in a state of readiness, discerning the times, and anchoring our hope in the unwavering sovereignty of God amidst all tribulations, whether personal or global.

Questions for Reflection

  • How does Jesus' "woe" in this verse challenge my understanding of God's character, particularly His justice and compassion?
  • In what ways might I be called to show empathy and practical care for the vulnerable in my own community or in the face of global crises?
  • What does this prophecy about Jerusalem teach me about the importance of heeding God's warnings and living in spiritual preparedness?

FAQ

Was the destruction of Jerusalem in 70 AD truly an act of "wrath upon this people" from God, or merely a historical tragedy?

Answer: While the destruction of Jerusalem in 70 AD was undeniably a historical tragedy with immense human suffering, the biblical text, particularly Luke 21:23, presents it as an act of "wrath upon this people." This signifies that it was not merely a random event but a consequence of divine judgment for the nation's persistent rejection of God's covenant, their prophets, and ultimately, the Messiah Himself. Jesus' prophecy frames it within the context of "days of vengeance" (Luke 21:22), indicating a divinely ordained recompense for their spiritual rebellion and the shedding of innocent blood (Matthew 23:35-36).

CHRIST-CENTERED FULFILLMENT

While Luke 21:23 primarily details the historical judgment on Jerusalem, its Christ-centered fulfillment extends beyond this event to reveal profound truths about Jesus' identity and redemptive work. The "wrath upon this people" foreshadows the ultimate judgment that Christ, as the righteous Judge, will execute upon all unrighteousness (John 5:22). Yet, the "woe" expressed by Jesus also reveals His deep compassion, even for those facing judgment, echoing His lament over Jerusalem in Luke 19:41-44. This compassion is ultimately manifested in His atoning sacrifice on the cross, where He willingly absorbed the "wrath" of God that humanity deserved, becoming the propitiation for our sins (Romans 3:25). Thus, for those who trust in Him, the ultimate "distress" and "wrath" have been averted, and they are offered refuge and salvation in the Lamb of God. The tribulations foretold in this verse, and indeed all tribulations, serve to highlight the urgent need for humanity to find shelter in Christ, who alone delivers us from the coming wrath (1 Thessalonians 1:10).

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Commentary on Luke 21 verses 20–28

Having given them an idea of the times for about thirty-eight years next ensuing, he here comes to show them what all those things would issue in at last, namely, the destruction of Jerusalem, and the utter dispersion of the Jewish nation, which would be a little day of judgment, a type and figure of Christ's second coming, which was not so fully spoken of here as in the parallel place (Mt. 24), yet glanced at; for the destruction of Jerusalem would be as it were the destruction of the world to those whose hearts were bound up in it.

I. He tells them that they should see Jerusalem besieged, compassed with armies (Luk 21:20), the Roman armies; and, when they saw this, they might conclude that its desolation was nigh, for in this the siege would infallibly end, though it might be a long siege. Note, As in mercy, so in judgment, when God begins, he will make an end.

II. He warns them, upon this signal given, to shift for their own safety (Luk 21:21): "Then let them that are in Judea quit the country and flee to the mountains; let them that are in the midst of it" (Of Jerusalem) "depart out, before the city be closely shut up, and" (as we say now) "before the trenches be opened; and let not them that are in the countries and villages about enter into the city, thinking to be safe there. Do you abandon a city and country which you see God has abandoned and given up to ruin. Come out of her, my people."

III. He foretels the terrible havoc that should be made of the Jewish nation (Luk 21:22): Those are the days of vengeance so often spoken of by the Old Testament prophets, which would complete the ruin of that provoking people. All their predictions must now be fulfilled, and the blood of all the Old Testament martyrs must now be required. All things that are written must be fulfilled at length. After days of patience long abused, there will come days of vengeance; for reprieves are not pardons. The greatness of that destruction is set forth, 1. By the inflicting cause of it. It is wrath upon this people, the wrath of God, that will kindle this devouring consuming fire. 2. By the particular terror it would be to women with child, and poor mothers that are nurses. Woe to them, not only because they are most subject to frights, and least able to shift for their own safety, but because it will be a very great torment to them to think of having borne and nursed children for the murderers. 3. By the general confusion that should be all the nation over. There shall be great distress in the land, for men will not know what course to take, nor how to help themselves.

IV. He describes the issue of the struggles between the Jews and the Romans, and what they will come to at last; in short, 1. Multitudes of them shall fall by the edge of the sword. It is computed that in those wars of the Jews there fell by the sword above eleven hundred thousand. And the siege of Jerusalem was, in effect, a military execution. 2. The rest shall be led away captive; not into one nations, as when they were conquered by the Chaldeans, which gave them an opportunity of keeping together, but into all nations, which made it impossible for them to correspond with each other, much less to incorporate. 3. Jerusalem itself was trodden down of the Gentiles. The Romans, when they had made themselves masters of it, laid it quite waste, as a rebellious and bad city, hurtful to kings and provinces, and therefore hateful to them.

V. He describes the great frights that people should generally be in. Many frightful sights shall be in the sun, moon, and stars, prodigies in the heavens, and here in this lower world, the sea and the waves roaring, with terrible storms and tempests, such as had not been known, and above the ordinary working of natural causes. The effect of this shall be universal confusion and consternation upon the earth, distress of nations with perplexity, Luk 21:25. Dr. Hammond understands by the nations the several governments or tetrarchies of the Jewish nation, Judea, Samaria, and Galilee; these shall be brought to the last extremity. Men's hearts shall fail them for fear (Luk 21:26), apopsuchontōn anthrōpōn - men being quite exanimated, dispirited, unsouled, dying away for fear. Thus those are killed all the day long by whom Christ's apostles were so (Rom 8:36), that is, they are all the day long in fear of being killed; sinking under that which lies upon them, and yet still trembling for fear of worse, and looking after those things which are coming upon the world. When judgment begins at the house of God, it will not end there; it shall be as if all the world were falling in pieces; and where can any be secure then? The powers of heaven shall be shaken, and then the pillars of the earth cannot but tremble. Thus shall the present Jewish policy, religion, laws, and government, be all entirely dissolved by a series of unparalleled calamities, attended with the utmost confusion. So Dr. Clarke. But our Saviour makes use of these figurative expressions because at the end of time they shall be literally accomplished, when the heavens shall be rolled together as a scroll, and all their powers not only shaken, but broken, and the earth and all the works that are therein shall be burnt up, Pe2 3:10, Pe2 3:12. As that day was all terror and destruction to the unbelieving Jews, so the great day will be to all unbelievers.

VI. He makes this to be a kind of appearing of the Son of man: Then shall they see the Son of man coming in a cloud, with power and great glory, Luk 21:27. The destruction of Jerusalem was in a particular manner an act of Christ's judgment, the judgment committed to the Son of man; his religion could never be thoroughly established but by the destruction of the temple, and the abolishing of the Levitical priesthood and economy, after which even the converted Jews, and many of the Gentiles too, were still hankering, till they were destroyed; so that it might justly be looked upon as a coming of the Son of man, in power and great glory, yet not visibly, but in the clouds; for in executing such judgments as these clouds and darkness are round about him. Now this was, 1. An evidence of the first coming of the Messiah; so some understand it. Then the unbelieving Jews shall be confined, when it is too late, that Jesus was the Messiah; those that would not see him coming in the power of his grace to save them shall be made to see him coming in the power of his wrath to destroy them; those that would not have him to reign over them shall have him to triumph over them. 2. It was an earnest of his second coming. Then in the terrors of that day they shall see the Son of man coming in a cloud, and all the terrors of the last day. They shall see a specimen of it, a faint resemblance of it. If this be so terrible, what will that be?

VII. He encourages all the faithful disciples in reference to the terrors of that day (Luk 21:28): "When these things begin to come to pass, when Jerusalem is besieged, and every thing is concurring to the destruction of the Jews, then do you look up, when others are looking down, look heavenward, in faith, hope, and prayer, and lift up your heads with cheerfulness and confidence, for your redemption draws night." 1. When Christ came to destroy the Jews, he came to redeem the Christians that were persecuted and oppressed by them; then had the churches rest. 2. When he comes to judge the world at the last day, he will redeem all that are his, from all their grievances. And the foresight of that day is as pleasant to all good Christians as it is terrible to the wicked and ungodly. Their death itself is so; when they see that day approaching, they can lift up their heads with joy, knowing that their redemption draws nigh, their removal to their Redeemer.

VIII. Here is one word of prediction that looks further than the destruction of the Jewish nation, which is not easily understood; we have it in Luk 21:24 : Jerusalem shall be trodden down of the Gentiles, till the times of the Gentiles be fulfilled. 1. Some understand it of what is past; so Dr. Hammond. The Gentiles, who have conquered Jerusalem, shall keep possession of it, and it shall be purely Gentile, till the times of the Gentiles be fulfilled, till a great part of the Gentile world shall have become Christian, and then after Jerusalem shall have been rebuilt by Adrian the emperor, with an exclusion of all the Jews from it, many of the Jews shall turn Christians, shall join with the Gentile Christians, to set up a church in Jerusalem, which shall flourish there for a long time. 2. Others understand it of what is yet to come; so Dr. Whitby. Jerusalem shall be possessed by the Gentiles, of one sort or other, for the most part, till the time come when the nations that yet remain infidels shall embrace the Christian faith, when the kingdoms of this world shall become Christ's kingdoms, and then all the Jews shall be converted. Jerusalem shall be inhabited by them, and neither they nor their city any longer trodden down by the Gentiles.

Matthew Henry (1662–1714) — Commentary on the Whole Bible. This section covers verses 20–28. Public domain.
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TertullianAD 220
On Monogamy
A third saying let them add, "Let us eat, and drink, and marry, for to-morrow we shall die; " not reflecting that the "woe" (denounced) "on such as are with child, and are giving suck," will fall far more heavily and bitterly in the "universal shaking" of the entire world than it did in the devastation of one fraction of Judaea.
TertullianAD 220
To His Wife Book I
For why should we be eager to bear children, whom, when we have them, we desire to send before us (to glory) (in respect, I mean, of the distresses that are now imminent); desirous as we are ourselves, too, to be taken out of this most wicked world, and received into the Lord's presence, which was the desire even of an apostle? To the servant of God, forsooth, offspring is necessary! For of our own salvation we are secure enough, so that we have leisure for children! Burdens must be sought by us for ourselves which are avoided even by the majority of the Gentiles, who are compelled by laws, who are decimated by abortions; burdens which, finally, are to us most of all unsuitable, as being perilous to faith! For why did the Lord foretell a "woe to them that are with child, and them that give suck," except because He testifies that in that day of disencumbrance the encumbrances of children will be an inconvenience? It is to marriage, of course, that those encumbrances appertain; but that ("woe") will not pertain to widows.
Hippolytus of RomeAD 235
Hippolytus Dogmatical and Historical Fragments
These things, then, being to come to pass, beloved, and the one week being divided into two parts, and the abomination of desolation being manifested then, and the two prophets and forerunners of the Lord having finished their course, and the whole world finally approaching the consummation, what remains but the coming of our Lord and Saviour Jesus Christ from heaven, for whom we have looked in hope? who shall bring the conflagration and just judgment upon all who have refused to believe on Him. For the Lord says, "And when these things begin to come to pass, then look up, and lift up your heads; for your redemption draweth nigh." "And there shall not a hair of your head perish." "For as the lightning cometh out of the east, and shineth even unto the west, so shall also the coming of the Son of man be. For wheresoever the carcase is, there will the eagles be gathered together." Now the fall took place in paradise; for Adam fell there. And He says again, "Then shall the Son of man send His angels, and they shall gather together His elect from the four winds of heaven." And David also, in announcing prophetically the judgment and coming of the Lord, says, "His going forth is from the end of the heaven, and His circuit unto the end of the heaven: and there is no one hid from the heat thereof." By the heat he means the conflagration. And Esaias speaks thus: "Come, my people, enter thou into thy chamber, (and) shut thy door: hide thyself as it were for a little moment, until the indignation of the Lord be overpast." And Paul in like manner: "For the wrath of God is revealed from heaven against all ungodliness and unrighteousness of men, who hold the truth of God in unrighteousness."
Eusebius of Caesarea (as quoted by Aquinas, AD 1274)AD 339
Catena Aurea by Aquinas
By the desolation of Jerusalem, He means that it was never again to be set up, or its legal rites to be reestablished, so that no one should expect, after the coming siege and desolation, any restoration to take place, as there was in the time of the Persian king, Antiochus the Great, and Pompey.

Now our Lord, foreseeing that there would be a famine in the city, warned His disciples in the siege that was coming, not to betake themselves to the city as a place of refuge, and under God's protection, but rather to depart from thence, and flee to the mountains.

For so in truth it was, that when the Romans came and were taking the city, many multitudes of the Jewish people perished in the mouth of the sword; as it follows, And they shall fall by the edge of the sword. But still more were cut off by famine. And these things happened at first indeed under Titus and Vespasian, but after them in the time of Hadrian the Roman general, when the land of their birth was forbidden to the Jews. Hence it follows, And they shall be led away captive into all nations. For the Jews filled the whole land, reaching even to the ends of the earth, and when their land was inhabited by strangers, they alone could not enter it; as it follows, And Jerusalem shall be trodden down of the Gentiles, until the times of the Gentiles be fulfilled.
Ambrose of MilanAD 397
EXPOSITION OF THE GOSPEL OF LUKE 10.26
Woe to those pregnant women, because they are heavy in body; they are too slow to escape danger. Woe to those for whom the yet unfelt pangs of future birth, by which every body is shaken, are the signs of future judgment, the beginnings of sorrows.
Ambrose of Milan (as quoted by Aquinas, AD 1274)AD 397
Catena Aurea by Aquinas
For the Jews thought that the abomination of desolation took place when the Romans, in mockery of a Jewish observance, cast a pig's head into the temple.

Now mystically, the abomination of desolation is the coming of Antichrist, for with ill-omened sacrilege he pollutes the innermost recesses of the heart, sitting as it is literally in the temple, that he may claim to himself the throne of divine power. But according to the spiritual meaning, he is well brought in, because he desires to impress firmly on the affections the footstep of his unbelief, disputing from the Scriptures that he is Christ. Then shall come desolation, for very many falling away shall depart from the true religion. Then shall be the day of the Lord, since as His first coming was to redeem sin, so also His second shall be to subdue iniquity, lest more should be carried away by the error of unbelief. There is also another Antichrist, that is, the Devil, who is trying to besiege Jerusalem, i. e. the peaceful soul, with the hosts of his law. When then the Devil is in the midst of the temple, there is the desolation of abomination. But when upon any one in trouble the spiritual presence of Christ has shone, the unjust one is cast out, and righteousness begins her reign. There is also a third Antichrist, as Arius and Sabellius and all who with evil purpose lead us astray. But these are they who are with child, to whom woe is denounced, who enlarge the size of their flesh, and the step of whose inmost soul waxes slow, as those who are worn out in virtue, pregnant with vice. But neither do those with child escape condemnation, who though firm in the resolution of good acts, have not yet yielded any fruits of the work undertaken. These are those which conceive from fear of God, but do not all bring forth. For there are some which thrust forth the word abortive before their delivery. There are others too which have Christ in the womb, but have not yet formed Him. Therefore she who brings forth righteousness, brings forth Christ. Let us also hasten to nourish our children, lest the day of judgment or death find us as it were the parents of an imperfect offspring. And this you will do if you keep all the words of righteousness in your heart, and wait not the time of old age, but in your earliest years, without corruption of your body, quickly conceive wisdom, quickly nourish it. But at the end shall all Judæa be made subject to the nations which shall believe, by the mouth of the spiritual sword, which is the two-edged word. (Rev. 1:16; 19:15.)
John Chrysostom (as quoted by Aquinas, AD 1274)AD 407
Catena Aurea by Aquinas
(adv. oppug. mon. vit.) He next assigns the cause of what he had just now said, For there shall be great distress in the land, and wrath upon this people. For the miseries that took hold of them were such as, in the words of Josephus, no calamity can henceforth compare to them.
Augustine of HippoAD 430
LETTER 199
Anyone can see that he refers to that city when Christ says, "When you shall see Jerusalem surrounded by an army, then know that its desolation is near." Anyone can see that these words refer to the last coming of the Lord when he says, "When you shall see these things come to pass, know that the kingdom of God is near." When he says, "Alas for those who are with child and for those who give suck in those days! Pray that your flight may not be in winter or on a sabbath. For then there will be great tribulation, such as has not been from the beginning of the world until now, no, and never will be." This passage is phrased in this way in Matthew and Mark so that it is uncertain whether it is to be understood of the destruction of the city or of the end of the world.… Luke has so arranged it that it seems to refer to the destruction of that city.
Augustine of Hippo (as quoted by Aquinas, AD 1274)AD 430
Catena Aurea by Aquinas
(ad Hesych. Ep. 199.) These words of our Lord, Luke has here related to show, that the abomination of desolation which was prophesied by Daniel, and of which Matthew and Mark had spoken, (Mat. 24, Mark 13.) was fulfilled at the siege of Jerusalem.

(ut sup.) And before this, Matthew and Mark said, And let him that is on the housetop not come down into his house; and Mark added, neither enter therein to take any thing out of his house; in place of which Luke subjoins, And let them which are in the midst of it depart out.

(uti sup.) But where Matthew and Mark have written, Neither let him which is in the field return back to take his clothes, Luke adds more clearly, And let not them that are in the countries enter thereinto, for these be the days of vengeance, that all the things which are written may be fulfilled.

(ubi sup.) Then Luke follows in words similar to those of the other two; But woe to them that are with child, and them that give suck in those days; and thus has made plain what might otherwise have been doubtful, namely, that what was said of the abomination of desolation belonged not to the end of the world, but the taking of Jerusalem.
Cyril of AlexandriaAD 444
COMMENTARY ON LUKE, HOMILY 139
To make his prediction even clearer and to mark more plainly the time of its capture, Jesus says, “When you have seen Jerusalem surrounded with armies, then know that its destruction is near.” Afterwards, he again transfers his words from this subject to the time of the consummation. He says, “There will be signs in sun and moon and stars, and upon the earth distress of nations in perplexity at the roaring of the sea and the waves, men fainting with fear and with foreboding of what is coming on the world; for the powers of the heavens will be shaken.” Since creation begins to be changed and brings unendurable terrors on the inhabitants of earth, there will be a certain fearful tribulation. There will also be souls departing to death. The unendurable fear of those things that are coming will be sufficient for the destruction of many.
Gregory the Dialogist (as quoted by Aquinas, AD 1274)AD 604
Catena Aurea by Aquinas
(Hom. 35. in Ev.) By patience then we possess our souls, because when we are said to govern ourselves, we begin to possess that very thing which we are. But for this reason, the possession of the soul is laid in the virtue of patience, because patience is the root and guardian of all virtues. Now patience is to endure calmly the evils which are inflicted by others, and also to have no feeling of indignation against him who inflicts them.
Bede (as quoted by Aquinas, AD 1274)AD 735
Catena Aurea by Aquinas
Hitherto our Lord had been speaking of those things which were to come to pass for forty years, the end not yet coming. He now describes the very end itself of the desolation, which was accomplished by the Roman army; as it is said, And when ye shall see Jerusalem compassed, &c.

(Ecc. Hist. lib. iii. c. 5.) The ecclesiastical history relates, that all the Christians who were in Judæa, when the destruction of Jerusalem was approaching, being warned of the Lord, departed from that place, and dwelt beyond the Jordan in a city called Pella, until the desolation of Judæa was ended.

But how, while the city was already compassed with an army, were they to depart out? except that the preceding word "then" is to be referred, not to the actual time of the siege, but the period just before, when first the armed soldiers began to disperse themselves through the parts of Galilee and Samaria.

And these are the days of vengeance, that is, the days exacting vengeance for our Lord's blood.

He says then, Woe to them that nurse, or give suck, as some interpret it, whose womb or arms now heavy with the burden of children, cause no slight obstacle to the speed of flight.

Which indeed the Apostle makes mention of when he says, Blindness in part is happened to Israel, and so all Israel shall be saved. (Rom. 11:25.) Which when it shall have gained the promised salvation, hopes not rashly to return to the land of its fathers.
BedeAD 735
On the Gospel of Luke
For there will be great distress upon the earth, and wrath upon this people. This distress and wrath have adhered as an inseparable companion to that people scattered among all nations up to this day, yet it is not believed to adhere perpetually. For after the Lord showed the order of the same distress or wrath, saying:
BedeAD 735
On the Gospel of Luke
Woe to those who are pregnant and those nursing in those days. Woe, in the presence of captivity, to those who are pregnant and those nursing, or suckling, as some interpret. For their wombs or hands burdened with the load of their children significantly hinder the necessity of flight. Read even the history of the Kings, where the wife of Jonathan, avoiding the evil of captivity with a hasty flight, received her son, who slipped from her bosom, permanently lame.
Theophylact of Ohrid (as quoted by Aquinas, AD 1274)AD 1107
Catena Aurea by Aquinas
But some say that the Lord hereby signified the devouring of children, which Josephus also relates.
Source: Quotations drawn from early Church Fathers and historical Christian theologians (AD 100–1500). Some quotes address the surrounding passage context rather than this verse alone.
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