### Core Meaning & Semantic Range
The Greek word **monóō**, represented by `{{G3443}}`, means **to isolate, i.e. bereave**. It appears only **1 time** in **1 unique verse** in the Bible. The core meaning is to **be desolate**.
### Biblical Occurrences & Contextual Analysis
The single use of `{{G3443}}` is found in the description of a **widow** `{{G5503}}` in [[1 Timothy 5:5]]. The verse specifies that a widow who is truly a widow and **desolate** places her trust in God. This state of being bereft is contrasted with her continuous devotion, as she "continueth in supplications and prayers night and day" [[1 Timothy 5:5]].
### Related Words & Concepts
Several related words clarify the context of being **desolate**:
* `{{G5503}}` **chḗra** (widow): This word identifies the person described as **desolate**, meaning "a widow (as lacking a husband), literally or figuratively". The instructions are to "Honour **widows** that are **widows** indeed" [[1 Timothy 5:3]].
* `{{G1679}}` **elpízō** (to expect or confide): This is the action of the **desolate** widow, who "trusteth in God" [[1 Timothy 5:5]]. The word also appears in the definition of faith as the "substance of things **hoped for**" [[Hebrews 11:1]].
* `{{G4357}}` **prosménō** (to adhere to, persevere in): This describes the widow's steadfastness. The verse states she "continueth in supplications and prayers" [[1 Timothy 5:5]]. It is also used to encourage believers to "**cleave unto** the Lord" [[Acts 11:23]].
### Theological Significance
The theological weight of `{{G3443}}` is demonstrated in its singular context.
* **Reliance in Bereavement:** Being **desolate** is presented as a condition that leads directly to trust in **God** `{{G2316}}`. The verse pairs the state of being isolated with the act of placing hope and confidence in God [[1 Timothy 5:5]].
* **Mark of a "Widow Indeed":** The term is used in conjunction with **óntōs** `{{G3689}}`, meaning **indeed** or **really**. This implies that being **desolate** is a key characteristic that distinguishes a widow who is truly reliant on God.
* **Action from Isolation:** The state of being **desolate** is not passive. It prompts the widow to "**continue in** supplications and prayers" [[1 Timothy 5:5]], turning her isolation into an occasion for steadfast devotion.
### Summary
In summary, `{{G3443}}` **monóō** provides a specific portrait of desolation. Although used only once, it defines a state of being utterly bereft and isolated. In its sole biblical appearance, this condition is not presented as a hopeless end, but as the very circumstance that characterizes a widow who places her complete trust in God and remains steadfast in prayer. The word illustrates how a state of earthly lack can become the foundation for profound spiritual reliance.