### Core Meaning & Semantic Range
The Greek word **gángraina**, represented by `{{G1044}}`, refers to an ulcer or "gangrene," and is translated as **canker**. Its definition stems from a root meaning "to gnaw," vividly capturing the consuming nature of the affliction. It appears only **1 time** in **1 unique verse**, making its single usage highly significant.
### Biblical Occurrences & Contextual Analysis
In its sole biblical appearance, `{{G1044}}` is used metaphorically to describe the destructive nature of false teaching. In [[2 Timothy 2:17]], the "word" of Hymenaeus and Philetus is said to "eat as doth a **canker**." This illustrates that their doctrine is not merely incorrect but is an active, spreading corruption that consumes spiritual health, much like gangrene consumes flesh.
### Related Words & Concepts
Several related words provide context for the action and effect of `{{G1044}}`:
* `{{G3542}}` **nomḗ** (pasture, feeding): While this word can refer to literal **pasture** [[John 10:9]], its figurative sense of "feeding" or spreading is used directly with **canker** in [[2 Timothy 2:17]]. The definition from the legend explicitly notes its use for the "spreading of a gangrene."
* `{{G2192}}` **échō** (have, hold): This common verb is used to denote possession, such as to **have** life [[John 10:10]] or peace [[John 16:33]]. In the primary verse, it is paired with `{{G3542}}` to form the phrase "will **eat**," describing the progressive and consuming action of the false words.
### Theological Significance
The theological weight of `{{G1044}}` is concentrated in its powerful imagery of spiritual disease.
* **Corrupting Influence of False Doctrine:** The word is used to issue a severe warning about the nature of heretical speech. It is not a static error but a dynamic, destructive force that spreads and causes spiritual decay [[2 Timothy 2:17]].
* **The Power of Words:** By likening the words of Hymenaeus and Philetus to a **canker**, Scripture emphasizes that speech can be a source of spiritual corruption that infects and harms the community of believers.
* **Contrast with Divine Truth:** The immediate context of this warning presents a contrast. While the canker of false teaching spreads, "the foundation of God standeth sure, **having** this seal, The Lord knoweth them that are his" [[2 Timothy 2:19]], highlighting the stability of truth versus the decay of error.
### Summary
In summary, **gángraina** `{{G1044}}` is a potent and graphic term used to define the perilous nature of unsound doctrine. Though mentioned only once, its depiction of a gnawing, spreading **canker** serves as a timeless and sobering metaphor. It powerfully illustrates how false teachings can consume the spiritual vitality of individuals and communities, standing in stark contrast to the life-giving, foundational truth of God.